Stature Flashcards
(13 cards)
Peak growth prior to puberty
5-6 cm/yr
Slight deceleration before puberty
Peak growth during puberty
SMR 3
In boys, occurs ~2 years after girls
In girls, occurs ~1.5 years before menarche
The earlier puberty occurs, the shorter the adult height.
Growth hormone deficiency
Congenital GHD
Presents ~6 months old (infancy) with slowed growth
-Micropenis
-hypoglycemia
- Septo-optic dysplasia
- breech
- prolonged jaundice
Delayed bone age
No family history
Nutrition deficiency
Underweight
Bone age normal
Crohn’s disease short stature
Can be the first symptom of Crohn’s disease
Order an ESR (elevated)
Constitutional delay (late bloomers)
More common in males \+Family history delayed bone age Delayed puberty Weight gain normal
Decrease growth rate on growth chart in teenage years
Usually hit puberty ~16 years old
Familial short stature
~/<5th percentile height
Normal growth velocity
Bone age equals chronological age
Parents heights are short
Syndromes that make you short
Turner syndrome
- often treated with growth hormone
- labs: karyotype, FSH, LH, TSH
Achondroplasia
Premature puberty
-androgens cause premature closure of growth plates
Hypothyroidism
-delayed bone age
Most important determinant of adult height in kids with tall stature
SMR (sexual maturity rating)
Genetic conditions that cause tall stature
Klinefelter syndrome
- normal at birth
- XXY
- gynecomastia
- small testicles
- Learning disabilities, normal intelligence usually
Marfan syndrome
- sudden-death, aortic aneurysm
- Arachnodactyly
Soto syndrome
- large head circumference
- cognitive defects
High caloric intake
Tall
Overweight
Normal to advanced bone age
Normal bone age
Nutrition deficiency
Familial short stature
Delayed bone age
Growth hormone deficiency
Constitutional delay (late bloomers)
Hypothyroidism