STDs (part 2- slide 119-173)- Schoenwald Flashcards

(80 cards)

1
Q

Epididymitis= Pain, swelling and inflammation of epididymis for < ___ weeks

Chronic epididymitis if Sx > ___months

A
  • 6 weeks

- 3 months

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2
Q

Epididymitis: demographic

-IF Sexually active men <35, most likely ______ or _____

A

**Gonorroeae or Chlamydia

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3
Q

Epididymitis:

IF Age >35, enteric organisms more likely ie _____

A

E coli

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4
Q

Epididymitis:

-unilateral or bilateral testicular pain?

A

*unilateral

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5
Q

Epididymitis:

tx for GC/Chlamydia=

A

**Ceftriaxone 250 mg IM x 1 plus doxycycline100 mg bid x 10 days (GC/chlamydia)

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6
Q

Epididymitis:

tx if enteric organism suspected:

A

**Levofloxacin 500 mg po q day x 10 days

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7
Q

Prostatitis is NOT part of STD tx guidelines, but less than 35 yo male with prostatitis–> MOST likely ______

A

GC/chlamydia

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8
Q

Prostatitis= acute swelling and inflammation of the prostate gland usually due to ______

A

*infection

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9
Q

Prostatitis: etiology?

A

**Etiology same as with epididymitis (GC/Chlamydia, or in older Pts enteric organisms)

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10
Q

Prostatitis:
Sx?
-Dx w/:

A
  • dysuria, pain with erection, fever, chills, low back pain
  • UA/culture pre and post prostate exam (pre prostate exam culture would be likely negative, but the post culture (after you massage prostate gland) would most likely be positive)
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11
Q

Prostatitis: tx?

A

-similar to epididymitis but longer duration.

(Ceftriaxone 250 mg IM x 1 plus doxycycline100 mg bid x 10 days (GC/chlamydia)
If enteric organism suspected-Levofloxacin 500 mg po q day x 10 days

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12
Q

normal prostate is about the size of a _____

A

walnut (and there’s no obstruction of the urethra)

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13
Q

Bacterial Vaginosis: Controversy: STD - yes or no

  • need for tx:
  • -in 1980: only if Pt complains
  • -in 2002: increased risk of:
A

Preterm birth / premature rupture of membranes

Amniotic fluid infection

Chorioamnionitis / Postpartum endometritis

PID

Postsurgical infection

Cervical intraepithelial neoplasia

Mucopurulent cervicitis

Acquisition of HIV infection

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14
Q

Bacterial Vaginosis= alteration in ______

A

**vaginal flora

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15
Q

_________ makes up 95% of normal vaginal flora

A

**lactobacillus

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16
Q

BV:

-list 5 known risk factors

A
New sex partners
Douching
Decrease in normal flora
Absence of barrier methods
IUDs
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17
Q

BV:

-MC etiology?

A

**Gardnerella vaginosis

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18
Q

BV:

-Wet prep shows _____** and positive _____ test

A

**Clue cells, positive whiff test

KNOW

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19
Q

BV:

-Discharge appearance, odor and vaginal pH?

A

**White discharge, fishy odor, pH >4.5

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20
Q

BV:

tx regimens:

A

**Metronidazole 500 mg BID for 7 days
or
Metronidazole gel 0.75%, 5 g intravaginally QD for 5 days
or
Clindamycin cream 5%, 5 g intravaginally q hs for 7 days

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21
Q

BV: tx in pregnancy

-symptomatic women should be treated due to:

A
  • **association with adverse pregnancy outcomes
  • Existing data do not support use of topical agents in pregnancy
  • Some experts recommend screening and treatment of asymptomatic women at high risk for preterm delivery (previous preterm birth) at the first prenatal visit; optimal regimen not established
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22
Q

BV tx in Pregnancy:

-Specific regimen ?

A

**Metronidazole 500 mg po bid x 7 days
or
Metronidazole 250 mg three times daily for 7 days
or
Clindamycin 300 mg twice daily for 7 days

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23
Q

BV: Management of Sex Partners

A

Woman’s response to therapy and the likelihood of relapse or recurrence not affected by tx of sex partner

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24
Q

Recurrent Vulvovaginal Candidiasis is defined as __ or more symptomatic episodes/year

A

4**

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25
Recurrent Vulvovaginal Candidiasis: | What is useful to confirm the dx and identify unusual species?
-**vaginal culture
26
Recurrent Vulvovaginal Candidiasis: - initial tx regimen= - Maintenance regimens=
- 7-14 days topical therapy or fluconazole 150 mg (repeat 72 hr) - Maintenance: clotrimazole, ketoconazole, fluconazole, itraconazole
27
For Non-Albicans Vulvovaginal Candidiasis (VVC)--> | tx regimen?
**longer duration of therapy with non-azole regimen
28
Vulvovaginal Candidiasis:Management of Sex Partners
- Tx not recommended - tx of male partners does not reduce frequency of recurrences in the female -*Male partners with balanitis may benefit from tx
29
The Pt cannot have ______ with usage of metronidazole
ALCOHOL** (KNOW!) --also w/ first trimester AVOID metronidazole, give the Pt clindamycin
30
Vulvovaginal Candidiasis: Tx in Pregnancy
- **Only topical intravaginal regimens recommended | - 7 days of therapy
31
Trichomoniasis: - organism? - is assoc. with ___x risk of HIV acquisition
- Protozoan= Trichomonas vaginalis*** | - 2-3x
32
Trichomoniasis: - Sx? (describe the discharge**) - Gold standard dx test=
**Diffuse, malodorous yellow to green discharge -**Gold Standard= historically wet prep, BUT NAAT is more sensitive and recommended by 2015 guideline= NEW gold standard (board exams will now have gold standard test for trich= NAAT
33
"strawberry cervix" =
**TRICHOMONIASIS
34
Trichomoniasis: | -1st line tx:
Metronidazole 2 gm orally in a single dose or Tinidazole 2 grams orally in a single dose
35
Trichomoniasis: | IFTreatment Failure--> next steps?
Re-treat with metronidazole 500 mg twice daily for 7 days - If repeated failure occurs, treat with metronidazole 2 gm single dose for 3-5 days - If repeated failure, consider metronidazole susceptibility testing through the CDC
36
Trichomoniasis: Management of Sex Partners
- Sex partners should be treated | - Avoid intercourse until therapy is completed and patient and partner are asymptomatic
37
``` Human Papillomavirus (HPV): -over ___ different strains/40 strains infect the genital area ```
100**
38
HPV: | -High risk (=oncogenic) are types ___ and ___
**16 & 18. (KNOW)
39
HPV: | -Low risk (nononcogenic)= Types __ and ___
6 & 11 (warts)
40
HPV and Cervical Cancer: | -infection is generally indicated by the detection of ____
HPV DNA**
41
HPV infection is causally associated with _____ cancer and probably other _______ squamous cell cancers (e.g. anal, penile, vulvar, vaginal)
* cervical cancer | - anogenital
42
Over ___% of cervical cancers have HPV DNA detected within the tumor -What routine screening ensures EARLY detection (and tx) of pre cancerous lesions?
-99% **Routine Pap smear!!!
43
Cervical cancer: - In the US-- ____ cases - Worldwide: ______ cases
- 14,000 cases and 5,000 deaths | - 450,000 cases and 200,000 deaths
44
Anogenital Warts: | -___% caused by HPV type 6 or Type ___
- **90% - Type 6 or type 11** KNOW!
45
Anogenital Warts: | -Sx?
Usually asymptomatic, but if large, can cause obstructive Sx
46
Papillomavirus Treatment: | -primary goal for tx of visible warts is=
* removal of symptomatic warts | - Therapy may reduce but probably does not eradicate infectivity
47
Papillomavirus: tx | -difficult to determine if tx reduces ________
transmission | -No laboratory marker of infectivity
48
Papillomavirus: | -Source of therapy guided by preference of patient, experience of provider, and _____
resources - No evidence that any regimen is superior - Locally developed/monitored treatment algorithms assoc. w/ improved clinical outcomes
49
Papillomavirus: | Acceptable alternative tx option may be to:
observe; possible regression/uncertain transmission
50
Papillomavirus/Warts: tx regimen | -Patient applied: ______
``` Podofilox 0.5% solution or gel or Imiquimod 5% cream Or Sinecatechins 15% ointment ```
51
Papillomavirus/Warts: tx regimen | Provider-administered: ________
``` Cryotherapy or Trichloroacetic or Bichloroacetic acid 80-90% or Surgical removal ```
52
Papillomavirus: tx in Pregnancy | -which ABX should NOT be used?
Imiquimod, podophyllin, podofilox, sinecatechins
53
Papillomavirus: tx in Pregnancy | Many specialists advocate _____ ______ due to possible proliferation and friability
*wart removal
54
Papillomavirus: tx in Pregnancy HPV types __ and ___ can cause respiratory papillomatosis in infants and children -Preventative value of cesarean section is ______; may be indicated for pelvic outlet obstruction
6, 11 -unknown
55
Women w/ STD hx may be at increased risk of ______ cancer
*cervical
56
Cervical Cancer Screening:Women with Hx of STDs - Clinics that offer pap screening without colposcopic f/u should arrange for _____ - Management of abnormal pap provided per:
referral -Interim Guidelines for Management of Abnormal Cervical Cytology (NCI Consensus Panel) --Emerging data support HPV testing for the triage of women with ASCUS Pap tests
57
``` HPV vaccines: Ages ____ (ACIP recommended) --FDA approved to age ___ ```
- 9-26 yo | - up to age 45
58
HPV vaccines: | -Gardisil quadravalent: Has coverage for which HPV types?
6,11,16 and 18
59
HPV vaccines: | -Gardisil 9 valent-->Has coverage for which types?
6,11,16,18,31,33,45,52,and 58
60
Scabies= parastic infection by the ___
**mite Sarcoptes scabiei
61
Scabies: | -Sx?
- **Intense itching | - contagious
62
Scabies: | -tx?
**Permethrin 5% cream to all areas of body Or Ivermectin 200 ug/kg po repeat in 2 weeks
63
Scabiesw/ Persistent Sx: | -Rash and pruritus may persist for ___
2 weeks
64
Scabiesw/ persistence >2 weeks: (indicates?)
tx failure, resistance, reinfection, drug allergy, cross reactivity with household mites
65
Scabies: - Pay attention to _______ of infected Pts - treat close contacts _____ - management includes washing: ______
* fingernails - empirically - Wash linens, bedding and clothing
66
Norwegian Scabies= an aggressive infestation in ______ (which population?)
**immunodeficient, debilitated, or malnourished
67
Norwegian Scabies: - ______ transmissibility - substantial tx failure with _____ or ______
- greater** | - topical scabicide or oral ivermectin
68
Norwegian scabies: | tx recommendations?
**combination topical scabicide with ivermectin or repeated treatments with ivermectin
69
Pediculosis Pubis=
Pruritus or lice or nits on pubic hair
70
Pediculosis Pubis: - management? - Tx regimens:
* *Decontaminate bedding and clothing - Recommended tx: - -Permethrin 1% - -Lindane 1% shampoo - -Pyrethrins with piperonyl butoxide
71
Pediculosis Pubis: - re-treatment may be necessary if ______ - tx of sex partners within:
* *sx persist | - the last month
72
**Vaccine Preventable STDs: list 4 Ex's
- Hep A - Hep B - Hep C - HPV
73
Hepatitis A: - incubation period: - Demographic ? - Associated with _____
**Incubation 28 days -MSM I-llegal drug users -Chronic liver disease, hepatitis B and C infection
74
Hepatitis B: | -Hx of _____
-**Hx of STD, multiple sex partners, sexually active MSM Illegal drug use - Household members, sex partners of those with chronic hepatitis B - Hemodialysis, occupational blood exposure
75
HPV: | How many vaccines available ?
2 available: Quadrivalent and 9 valent
76
HPV: | Quadrivalent Vaccine covers _____ (which HPV types?)
HPV 16 and 18 (cancer associated) HPV 6 and 11 (wart)
77
HPV: | 9 valent vaccine covers which HPV types?
HPV 6, 11, 16, 18, 31, 33, 45, 52, 58
78
Hepatitis C: - how common? - is it sexually transmitted?
- **MC bloodborne infection in US | - Not efficiently sexually transmitted but persons at risk may seek tx for other STDs
79
Hepatitis C: - coinfection with ____ common - Vaccine available?
HIV** -NO vaccine
80
"Burrowing on skin"=
think scabies!!! tx: permethrin full body, head to toe (scabies can be sexually transmitted, can be spread through pets, etc)