STEP 1-Toxins and Antidotes Flashcards by Steven Madsen

Q

Acetaminophen

A

N-acetylcysteine (GSH replenish)

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Q

AChE inhibitors (organophosphates)

A

Atropine followed by pralidoxime

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Q

Amphetamines (basic)

A

NH4CL (acidify urine)

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Q

Antimuscarinic/anticholinergic agents

A

physostigmine salicylate (control hyperthermia)

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Q

Benzodiazapines

A

Flumazenil

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Q

B-blockers

A

glucagon

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Q

Carbon Monoxide

A

100%/hyperbaric O2

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Q

Copper/arsenic/gold

A

penicillamine

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Q

cyanide

A

Nitrite + thiosulfate, hydroxocobalamine

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Q

Digitalis

A

Anti-dig FAB fragments

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Q

Heparin

A

Protamine sulfate

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Q

Iron

A

Deferoxamine, deferasirox

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Q

Lead

A

EDTA, dimercaprol, succimer, penicillamine

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Q

Mercury, arsenic, gold

A

Dimercaprol (BAL), succimer

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Q

Methanol/ethylene glycol

A

fomepizole > ethanol, dialysis

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Q

Methemoglobin

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A

methylene blue, vitamin C

Q

Opioids

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A

Naloxone

Q

Salicylates

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A

NaHCO3 (alkalinize urine), dialysis

Q

TCA’s

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A

NaHCO3 (alkalinize plasma)

Q

tPA, streptokinase, urokinase

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A

Aminocaproic acid

Q

Warfarin

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A

Vitamin K, plasma (if active bleeding)