Step 2 CK Flashcards

1
Q

M spike

A

Multiple myeloma

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2
Q

Splinter hemorrhages

A

Bacterial endocarditis

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3
Q

Janeway lesions

A

Bacterial endocarditis

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4
Q

Osler’s nodes

A

Bacterial endocarditis

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5
Q

Roth spots

A

Bacterial endocarditis

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6
Q

Splitting defense mechanism

A

Borderline personality disorder

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7
Q

SSPE

A

Measles

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8
Q

Sub-epithelial humps

A

PSGN

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9
Q

Coca Cola urine

A

PSGN

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10
Q

Succinylcholine

A

Malignant hyperthermia

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11
Q

t(2;5)

A

Anaplastic large cell lymphoma

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12
Q

Philadelphia chromosome

A

CML

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13
Q

t(15;17)

A

APL

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14
Q

t(8;14)

A

Burkett’s lymphoma

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15
Q

t(9;22)

A

CML

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16
Q

t(11;14)

A

Mantle cell lymphoma

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17
Q

t(11;18)

A

MALT lymphoma

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18
Q

t(11;22)

A

Ewing’s sarcoma

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19
Q

t(14;18)

A

Follicular lymphoma

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20
Q

Tartrate-resistant acid phosphatase (TRAP) positive cells

A

Hairy cell leukemia

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21
Q

Teardrop cell (Dacrocyte)

A

Myelofibrosis

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22
Q

Terminal deoxynucleotidyl transferase (TdT)

A

ALL

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23
Q

Thayer-Martin agar

A

Neisseria gonorrhea

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24
Q

Thenar eminence atrophy

A

Carpal tunnel syndrome

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25
Q

Tubomammilary nucleus

A

Histamine

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26
Q

Tzank smear

A

HSV or VZV

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27
Q

Undulating fever

A

Brucella

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28
Q

U waves on EKG

A

HYPOkalemia

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29
Q

Ventral tegmental area

A

ACh and Dopamine

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30
Q

“Worst headache of my life”

A

SAH

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31
Q

Wrist drop

A

Radial nerve injury

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32
Q

Foot drop

A

Common perineal nerve injury

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33
Q

Musty body odor in infant

A

Phenylketonuria

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34
Q

NADPH oxidase deficiency

A

Chronic granulomatous disease

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35
Q

Negri bodies

A

Rabies virus

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36
Q

Opening snap murmur

A

Mitral stenosis

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37
Q

Orange bodily fluids

A

Rifampin use

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38
Q

“Orphan Annie eye” nuclei

A

Papillary thyroid carcinoma

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39
Q

P-ANCA

A

Eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome )

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40
Q

C-ANCA

A

Granulomatosis with polyangiitis (formerly called Wegener’s)

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41
Q

Post-coital bleeding

A

cervical cancer

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42
Q

Peaked T waves on EKG

A

HYPERkalemia

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43
Q

Pigeon droppings

A

Cryptococcus

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44
Q

Chondrocalcinosis

A

Pseudogout

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45
Q

(+) birefringent rhomboid crystals

A

Pseudogout

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46
Q

(-) birefringent needle crystals

A

Gout

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47
Q

Pregnancy

A

Respiratory alkalosis

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48
Q

PTHrP

A

SCC of the lung

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49
Q

“Punched out” lesions on X-ray

A

Multiple myeloma

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50
Q

Pufferfish

A

Tetrodotoxin

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51
Q

Pulsus paradoxus

A

Cardiac tamponade

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52
Q

Ragged, red muscle fibers

A

Mitochondrial myopathy

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53
Q

Malar “butterfly” rash

A

SLE

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54
Q

Raphe nucleus

A

5-HT

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55
Q

Right angle (90) branching hyphae

A

Mucor

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56
Q

Romana’s sign

A

Chaga’s disease

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57
Q

Rosenthal fibers

A

Pilocytic astrocytoma

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58
Q

Rotary nystagmus

A

PCP use

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59
Q

“Seal-like” barking cough

A

Croup

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60
Q

Self-mutilating behavior

A

Lesch-Nyhan syndrome

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61
Q

HGPRT deficiency

A

Lesch-Nyhan syndrome

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62
Q

Situs inversus

A

Kartagener syndrome

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63
Q

Skip lesions

A

Crohn’s disease

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64
Q

Smudge cells

A

CLL

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65
Q

Fibrillin-1

A

Marfan syndrome

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66
Q

FGFR3

A

Achrondroplasia

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67
Q

Flattened T waves

A

HYPOkalemia

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68
Q

Fructokinase deficiency

A

Essential fructosuria

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69
Q

Galactose-1-phosphate uridyltransferase deficiency

A

Classic galactosemia

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70
Q

Gottron papules

A

Dermatomyositis

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71
Q

Guarnieri bodies

A

Poxvirus

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72
Q

Dix-Hallpike maneuver

A

BPPV

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73
Q

Haloperidol

A

Tardive dyskinesia

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74
Q

Halothane

A

Malignant hyperthermia

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75
Q

HLA-B8

A

Grave’s disease

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76
Q

HLA-B27

A

Ankylosis spondylitis

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77
Q

HLA-B51

A

Behcet syndrome

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78
Q

HLA-CW6

A

Psoriasis vulgaris

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79
Q

HLA-DQ1

A

Pemphigus vulgaris

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80
Q

HLA-DR3

A

Grave’s disease

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81
Q

HLA-DR4

A

RA

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82
Q

HLA-DR5

A

Hashimoto’s thyroiditis

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83
Q

Homer-Wright rosettes

A

Neuroblastoma or Medulloblastoma

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84
Q

HLA-DR5

A

Hashimoto’s thyroiditis

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85
Q

Hypersegmented neutrophils

A

B12 deficiency

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86
Q

Indian ink stain

A

Cryptococcus neoformans

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87
Q

Iron toxicity

A

Deferoxamine

88
Q

Lead toxicity

A

Succimer

89
Q

“Lead pipe” sign

A

Ulcerative colitis

90
Q

“Lead pipe” sign

A

Ulcerative colitis

91
Q

Locus coeruleus

A

Norepinephrine

92
Q

McBurney’s point

A

Appendicitis

93
Q

Murphy’s sign

A

Cholecystitis

94
Q

Krunkenburg tumor

A

Ovarian cancer

95
Q

Elevated 5-HIAA

A

Carcinoid syndrome

96
Q

22q11.2

A

DiGeorge syndrome

97
Q

AFP

A

Hepatocellular carcinoma

98
Q

Narrow-angle branching hyphae

A

Aspergillus

99
Q

Spaghetti and meatballs

A

Tinea versicolor

100
Q

ADA deficiency

A

SCID

101
Q

Anti-centromere Ab

A

Limited systemic sclerosis

102
Q

Anti-CCP

A

RA

103
Q

Anti-desomosome

A

Pemphigus valgaris

104
Q

Anti-sdDNA

A

SLE

105
Q

Anti-gliadin

A

Celiac disease

106
Q

Anti-GBM

A

Goodpasture syndrome

107
Q

Anti-hemidesmisome

A

Bullous pemphidoid

108
Q

Anti-histone

A

Drug-induced lupus

109
Q

Anti-Jo-1

A

Polymyositis

110
Q

Anti-La (SS-B)

A

Sjogren’s syndrome

111
Q

Anti-microsomal

A

Hashimoto’s thyroiditis

112
Q

Anti-Ro (SS-A)

A

Sjogren’s syndrome

113
Q

Anti-Scl-70

A

Diffuse systemic sclerosis

114
Q

Anti-Smith

A

SLE

115
Q

Anti-smooth muscle

A

Autoimmune hepaitits

116
Q

Anti-TSI (thyroid stimulating immunoglobulin)

A

Grave’s disease

117
Q

Anti-TPO (thyroperoxidase)

A

Hashimoto’s thyroiditis

118
Q

Anti-U1RNP

A

Mixed connective tissue disease

119
Q

Apple-Green birefringence on Congo red stain

A

Amyloidosis

120
Q

Apple-Green birefringence on Congo red stain

A

Amyloidosis

121
Q

“Apple core” lesions

A

Colorectal cancer

122
Q

“Ash leaf” spots

A

Tuberous sclerosis

123
Q

Auer rods

A

AML

124
Q

Beta-sheets in gray matter

A

Creutzfeldt-Jakob disease

125
Q

Basophilia

A

CML

126
Q

Basophilic stippling

A

Lead poisoning

127
Q

Bat bite

A

Rabies

128
Q

Bence-Jones proteins

A

Multiple myeloma

129
Q

Bicuspid aortic valve

A

Turner syndrome

130
Q

Bite cell (Degmacyte)

A

G6PD deficiency

131
Q

Black urine

A

Alkaptonuria

132
Q

Bluish-black sclarae

A

Alkaptonuria

133
Q

Brown tumor

A

Osteotis fibrosa cystica

134
Q

Bruton’s tyrosine kinase deficiency

A

X-linked agammaglobulinemia

135
Q

Burr cell (Echinocyte)

A

Pyruvate kinase deficiency

136
Q

CA 19-9

A

Pancreatic cancer

137
Q

CAG trinucleotide repeat

A

Huntington’s disease

138
Q

CD14

A

Monocyte/Macrophage lineage

139
Q

CD1a

A

LCH

140
Q

Birbeck granules

A

LCH

141
Q

Charcot_Leyden crystals

A

Asthma

142
Q

CGG trinucleotide repeat

A

Fragile X

143
Q

Clue cells

A

Bacterial vaginosis

144
Q

Cough, Coryza, Conjunctivitis

A

Measles

145
Q

Cowdry bodies

A

Herpes virus

146
Q

CTG trinucleotide repeat

A

Myotonic dystrophy

147
Q

Currant jelly

A

Klebsiella pneumoniae

148
Q

Target sign on X-ray

A

Intussusception

149
Q

Kerley B lines

A

CHF

150
Q

Curschmann’s spirals

A

Asthma

151
Q

Dermatitis herpeiformis

A

Celiac disease

152
Q

Dew drops on a rose petal

A

VZV and HSV

153
Q

Double bubble sign on X-ray

A

Duodenal atresia

154
Q

Erythema chronic migrans

A

Lyme disease

155
Q

Esophageal rupture

A

Boerhaave syndrome

156
Q

Calf pseudohypertrophy

A

Musclar dystrophy

157
Q

Caudate degeneration

A

Huntington’s disease

158
Q

Continuous “machine-like” murmur

A

PDA

159
Q

Pstosis, anhydrous, miosis

A

Horner’s syndrome

160
Q

Clenched fists w/ overlapping fingers

A

Edward’s syndrome

161
Q

Hyperorality

A

Kluver-Bucy syndrome

162
Q

Red urine in the morning

A

Paroxysmal nocturnal hemoglobinuria

163
Q

Webbed neck

A

Turner syndrome

164
Q

Cystic hygroma

A

Turner syndrome

165
Q

Shield chest

A

Turner syndrome

166
Q

Horseshoe kidney

A

Turner syndrome

167
Q

Harsh “Creschendo-decrescendo” murmur

A

Aortic stenosis

168
Q

Recurrent epistaxis

A

Osler-Weber-Rendu syndrome

169
Q

“Bamboo spine”

A

Ankylosing spondylitis

170
Q

“Boot-shaped” heart

A

Tetralogy of Fallot

171
Q

Apical lung tumor

A

Pancoast tumor

172
Q

Horner’s syndrome

A

Pancoast tumor

173
Q

Chocolate cyst

A

Endometrosis

174
Q

“Delta wave” on EKG

A

WPW syndrome

175
Q

Heterophile Abs

A

Mononucleosis

176
Q

“Honeycomb” lung

A

Intersticial pulmonary fibrosis

177
Q

Large granules in phagocytes

A

Chediak-Higashi syndrome

178
Q

“Onion-skin” appearance of bone

A

Ewing sarcoma

179
Q

“Rib notching” on X-ray

A

Coarctation of aorta

180
Q

“Thumbprint sign” on X-ray

A

Epiglottitis

181
Q

Trastuzumab

A

Heart failure

182
Q

Imatinib

A

CML Tx

183
Q

Trastuzumab

A

HER-2+ breast cancer

184
Q

Mifepristone

A

Medical abortion

185
Q

Natalizumab

A

Multiple sclerosis

186
Q

Dantrolene

A

Malignant hyperthermia Tx

187
Q

“Steeple sign” on CXR

A

Croup

188
Q

Croup

A

Parainfluenza

189
Q

“Shopping cart” sign

A

Spinal stenosis

190
Q

“Globular” joint appearance

A

Osteoarthritis

191
Q

Baker’s cyst

A

Osteoarthritis

192
Q

Osteophytes

A

Osteoarthritis

193
Q

“Moth-eaten” appearance on X-ray

A

Gout

194
Q

Quotidian fever

A

Still’s disease

195
Q

Evanescent rash

A

Still’s disease

196
Q

Pellagra

A

Niacin deficiency

197
Q

Dermatitis, diarrhea, dementia

A

Niacin deficiency

198
Q

Honey-colored crusts

A

Impetigo

199
Q

Targetoid plaques

A

Erythema multiforme

200
Q

Red palms

A

Pregnancy or cirrhosis

201
Q

Kayser-Fleischer rings

A

Wilson’s disease

202
Q

Wilson’s disease

A

Copper

203
Q

Bronze diabetes

A

Hemochromatosis

204
Q

Harsh, blowing, holosystolic murmur with a thrill

A

VSD

205
Q

Diastolic “rumble”

A

ASD

206
Q

Eisenmenger syndrome

A

ASD

207
Q

Widened pulse pressure

A

Aortic regurgitation

208
Q

Water-hammer pulse

A

Aortic regurgitation

209
Q

Corrigan pulse

A

Water-hammer pulse

210
Q

Austin flint murmur

A

Aortic stenosis

211
Q

Holosystolic murmur at the apex

A

Mitral regurgitation

212
Q

Blowing holosystolic murmur

A

Tricuspid regurgitation

213
Q

Pulsatile liver

A

Tricuspid regurgitation

214
Q

Mid-systolic or late-systolic clicks and mid-to-late systolic murmur

A

MVP

215
Q

Tet spells

A

Tetralogy of Fallot

216
Q

Pallor, pain, pulselessness, paresthesias, paralysis, parlor

A

Acute arterial occlusion

217
Q

Luetic heart

A

Syphilitic aortitis