Step 3 Flashcards

(669 cards)

1
Q

pain, redness, vision loss, constricted and irregular pupil

A

anterior uveitis (iritis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

severe photophobia with difficulty keeping eye open

A

infectious keratitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

corneal foreign body tx most common staph /contacts pseudomonas

A

erythromycin, cipro

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

drusen spots with central vision loss

A

dry macular degeneration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

blood vessels from choroid grow behind retina causing detachement

A

wet macular degeneration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

chronic gradual loss of peripheral vision and tx

A

open angle glaucoma, latanoprost, timolol, carbonic anhydrase inhibitors -zolamide meds

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

acute eye pain, headache, injection and tx

A

close angle glaucoma. acetazolamide, timolol, pilocarpine, mannitol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

sudden, severe with temporal sparring, amarosis fugax. pale fundus with cherry red spot

A

central retinal artery occlusion. ocular massage and acetazolamide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

subacute, blood and thunder

A

central retinal vein occulusion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

floaters, viterous hemorrhage and retina elevation

A

retinal detachement, surgery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

visual haze floaters, dark streaks, decreased red reflex

A

vitreous hemorrhage, bed rest with elevation 30-45%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

posterior nose bleed occurs where

A

sphenopalatine artery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

bone greater than air, weber louder in affected

A

conductive most commonly caused by otosclerosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

air greater than bone, weber louder in normal

A

sensorineural

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

pruritic, lichenified plaques on flexor surfaces

A

atopid dermatitis (eczema) topical steroids or topical tacrolimus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

immune mediated Type IV hypersensitivity rash acute causing papular lesions, vesicles, weeping erosions. chronically causes hyperkeratosis and lichenification

A

contact dermatitis, steroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

immune mediated skin disease , nails with pitting and onychiolysis classically involves the distal interphalangeal joints

A

psoriasis, steroids, light exposure, methotrexate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

tender red or violet nodules common in women, sarcoidoisis, inflammatory bowel disesae typically after recent URI or diarrheal illness. red nodules without ulceration on the shins

A

erythema nodosum , nsaids, potassium iodide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

looks like acne without pimples, flushing from spicy food, rhinophyma

A

rosacea - cleansers, metronidazole. potentally doxycycline, tretinoin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

acute inflammatory disease type IV hypersensitity, occures after sulfa drugs, rapidly progressive, symmetric lesions, targetoid papules on hands and palms

A

erythema multiforme - histamne blockers, prednisone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

autoimmune disease targeting desmoglein with oral lesions and nikolsky sign. flaccid bullae

A

pemphigus vulgaris - steroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

autoimmune disease against basement membrane with large tense bullae

A

bullous pemphigoid, steroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

pearly papules with central depression that is ulcerated on sun exposed areas

A

basal cell carcinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

annular plaques with a thin scale and central clearing

A

tinea corporis, griseofulvin, itraconazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
red, scaly soles with maceration and fissuring bwtween toes
tinea pedis - friseofulvin, terbinafine
26
hypopigmented macules in areas of sun , reddish brown in winter
tinea versicolor - itraconazole
27
hyperkeratosis and yellowing of the nail plate
onychomycosis, terbinafine
28
erythema and scaling of the scalp with thickened, broken off hairs and scalp kerion
tinea capitis - griseofulvin, itraconazole
29
pink plaques with scale or eroision spread to lymph nodes, arsenic exposure
squamous cell carcinoma
30
typical substernal chest pressure or shortness of breath that is exacerbated by exertion and relieed by rest or nitroglycerin
stable angina
31
any new angina in previously asymptomatic patients or accelerating or new angina at rest
unstable angina
32
true or false DM is a CAD risk equivalent
true
33
what determines the difference between unstable angina and NSTEMI
presence of elevated troponin
34
s4, crackles, venous destension after acute MI
Heart failure, dont give b-blocker give MONA BASH if stable and no signs of heart failure
35
what drugs improve mortality after MI
aspirin, b-blockers, ACEI, statins, anti platelet agents
36
post TPA in MI with decreased EF and prolonged QRS
cardiac resynchronization
37
post MI with symptoms and decreased EF <35%
give ICD
38
symptoms of HF, diastolic murmur heard best at apex with an opening snap associated with rheumatic fever
mitral stenosis, HR control
39
blowing systolic murmur at the apex and radiates to the axilla if acute leads to rapid pulmonry edema, cardiogenic shock, ruptured chordae tendinae due to MI usually and ultimately leads to AF
mitral regurgitation acute needs surgery chronic needs repair EF <60
40
midsystolic click, increased by valsalva maneuvers presents with palpitations or dyspnea
mitral valve prolapse
41
systolic crescendo-decrescendo murmur radiating to the carotids along the right sternal border, parvus et tardus presents with chest pain, syncope, HF, shortness of breath
aortic stenosis avoid overdiuresis do surgery
42
diastolic murmur along left sternal border with wide pulse pressure radiate to apex
aortic regurgitation - afterload reduction with ACE and hydralazine
43
systolic crescendo and decrescendo murmur at the left sternal boarder that is worse on standing and valsalva
Hypertrophic obstructive cardiomyopathy
44
caused by alcohol or tachycardia presents with ischemia, tachycardia, HTN, or chagas
dilated cardiomyopathy - ACE, ARB, B-blockers, spironolactone, digoxin
45
findings show LVDH and low voltage on EKG caused by sarcoid, amyloidosis, hemochromatosis, cancer, and glycogen storage
restrictive cardiomyopathy
46
ventricular septum hypertrophy that is not symmetric that is generally due to autosomal cardiac sarcomere in a dominant pattern associated with sudden cardia death
hypertrophic cardiomyopathy give b-blocker, verapmil or dysopyramide
47
distant or muffled heart sounds, incrased JVP, and pulsus paradoxus
pericardial effusion
48
postprandial abdominal pain, food fear, bloody diarrhea
mesenteric ischemia
49
gemfibrozil and nictoinic acid do what
increase HDL and decrease triglycerides
50
fever, rigors, HF, neurologic impairment, back pain, roth spots (white hemorrhages on retina), osler nodes, janeway lesions, pulmonary symptoms, (systemic emboli)
acute endocarditis, needs surgery for hemodynamic istability, heart failure, valve destruction give prophylaxsis with PCN for dental procedures
51
strep bovis associated with
gi malignancy
52
any patient with s aureus bacteremia needs
evaluation for endocarditis , dukes criteria
53
hip pain preceded by URI
toxic synovitis
54
ulnar shaft fracture with radial head dislocation
Monteggia fracture
55
distal 1/3 radius fracture with a distal radioular dislocation
galeazzi fracture
56
FOOSH injury - distal radial fracture with dorsal displacement
colles fracture
57
this fracture needs splinting even if there is tenderness in the area due to frequent development of avascular necrosis
scaphoid fracture
58
proximal fibula injury aka
maisonneuve fracture
59
shoulder disloaction typically causes
axillary nerve injury
60
supracondylar fractures lead to what
radial nerve injury
61
narrow regular complex tachycardia is typically, tx
SVT, adenosine
62
narrow irregular complex is typically, tx
AF, rate control metoprolol or diltiazem
63
wide complex tachycardia is typically , tx
VT, amiodarone
64
develops slowely over 24 hours and freatures rigidity rather than clonus (due to drugs)
neuroleptic malignant syndrome
65
indication for emergent dialysis - AEIOU
``` acidosis - can be fixed with bicarb electrolytes - hyperkalemia Ingestion - lithium or aspirin overload - kidney failure uremia - encephalopathy, serositis, pericarditis ```
66
herb used for BPH, causes
saw palmetto, increased bleeding
67
herm used for anxiety and insomnia, causes
kava kava, liver toxicity
68
herb used for depression, causes
st. johns wart, serotonin syndrome, decreased INR, digoxign toxicity, HTN crisis
69
Herb used for HLD
Garlic
70
Herb used for High triglycerides
fish oil
71
herb used for osteoarthritis
glacosamin and chondritin
72
used after menopause, causes
black cohosh, liver toxicity
73
herb used for memory enchancement, causes
ginko biloba, bleeding and intracranial bleeding
74
herb used for ulcers and virus, causes
licorice, HTN, hypokalemia
75
herb used for weight loss, causes
ephedra, HTN, sudden death, stroke, seizure
76
herb used for weight loss in china, causes
aristolochic acid, nephrotoxicity (RTA)
77
toxidrome presents with diarrhea, urination, miosis, bronchorrhea, bronchospasm, bradycardia, emesis, lacrimation, salivation, examples
cholinergic , mushrooms, organophosphates, pilocarpine, pyridostigmine
78
toxidrome presents with fever, flushing, dry mucous membranes, psychosis, mydraisis, tachycardia, and urinary retension, examples
anticholinergic - antihistamines, antipsychotics, atropine, jimson weed, scopolamine, TCA
79
toxidrome presents with coma, respiratory depression, and miosis, examples
opiods, heroin, morphine, oxycodone
80
toxidrome presents with CNS depression, respiratory depression, and coma, examples
sedative hypnotic , alcohol, barbs, benzo
81
toxidrome presents with disorientation, panic, seizures, hypertension, tachycardia, tachypnea, examples
sympathomimetics, amphetamines, cocaine, PCP
82
toxidrome presents with tremor, torticollis, trismus, rigidity, oculogyric crisis, opisthotonos, dysphonia, and dysphagia
extrapyramidal - haloperidol, metoclopramide, phenothiazines
83
opiate overdose tx
naloxone - may cause pulmonary edema
84
anticholinergic overdose treatmetn
benzo for symptom control
85
sympathomimetic toxidrome tx
benzodiazepine
86
organophasphate tx
atropine
87
hallucinogenic toxidrome tx
benzodiazepine
88
ethylene glycol ingestion tx
fomepizole or ethanol
89
monkey bites transmit this which has 80% fatality rate
Herpes B virus, treat with valacyclovir
90
anaphylactic - igE mediated
type I
91
cytotoxic antibody mediated
type II
92
immune complex mediated
Type III
93
type IV Delayed (CD4 mediated)
Type IV
94
difference between heat exhaustion and stroke
temperature dysregulation, AMS, and paradoxical shivering
95
associated with explosive exit wound, causes VF and due to household or commercial electricity
alternating current, worst kind
96
electricity causes discrete exit wound and asytole due to batteries, industry, and lightning
direct c urrent
97
traume and loss of vision with vitreous humor leak and teardrop shaped pupil, tx
puptured glove, eye shield
98
dental avulsion treatment
reimplant, rinse but dont scrub
99
polyuria, polydipsia, and polyphagia
DM
100
aspart
novolog
101
lispro
humalog
102
regular
humulin
103
glargine
Lantus
104
acidemia causes potassium to shift where to cause what
extracellulary, hyperkalemia
105
hyperglycemia with neurolgic symptoms
HHS
106
hyperglycemia with hyperventilation and abdominal pain
DKA
107
presents with fatigue, weight gain, constipation (ileus), dry skin with increased TSH and decreased T4
primary hypothyroidism, levothyroxine
108
altered mental statues, hypothermia, and hemodynamic instability
myxedema coma, levothyroxine
109
weight loss, tachycardia, anxiety, diarrhea, afib, tremor
primary hyperthyroidism, PTU or methimazole
110
high fever, tachycardia, cardiac failure, dehydration, altered mental statues
thyroid storm, propranolol for tachycardia glucocorticoids to block t4 conversion methimazole or PTU
111
presents like primary hyperthyroidism but has increased TSH and T4 due to adenoma usually
2nd hyperthyroidism, remove tumor, b-blockers
112
atibody against TSH receptor, diffuse pailness goiter, proptosis, pretibial myxedema
graves disease, ptu or methimazole prior to ablation
113
tender thyroid usually hyperthyroidism folled by hypothyroidism in setting of viral illness
subacute thyroiditis, NSAIDS
114
painless thyroid enlargement with anti TPO antibody present
hashimoto thyroditis
115
what trimester do you gie methimazole
2-3rd
116
wat trimester do you give PTU
1st
117
what is the difference between hot nodule and cold nodule
hot noduels are rarely malignant
118
cervical lymphadenopathy, dysphagia, dyspnea, and hoarseness
thyroid cancer
119
most common thyroid cancer
papillary spreads lymphatically
120
thyroid cancer spreads through blood to bone and lungs
papillary
121
tumor of parafollicular c cells that secrete calcitonin and assoicated with MEN 2A or 2B
medullary
122
undifferentiated thyroid cancer with poor prognosis
anaplastic
123
this is the best marker to determine if thyroid tissue remains or cancer of the thyroid has returned
thyroglobulin
124
presents at fatigue, constipation, polyuria, polydipsia and abdominal pain with increase in PTH and Calcium
priamry hyperparathyroidism tx acutely with IV hydration and furosemide
125
presents as fatigue, constipation, polyuria, polydipsia and abdominal pain with decreased or normal PTH and increased calcium
secondary hyperparathyroidism
126
presents with altered mental statues, polyuria, short QT syndrome, and dehydration in the setting of high calcium
hypercalcemic crisis >13, dialysis
127
t score > -1
normal
128
tscore -1 to -2.5
osteopenia
129
tscore
osteoporosis, tx -dronate drugs then raloxifene
130
presents as skin atrophy, proximal muscle weakness, moon face, buffalo hum, psychiatric disturbances, hypertension, hyperglycemia, growth retardation, hisutisim, what is the best test
hypercortisolism (cushings), dexamethasone test to mesaure cortisol excess
131
for dexamethsone cortisol testing if cortisol is normal cortisol is high
not cushing | do high dose dexamethasone supression test
132
on high dose dexamthasone supression testing acth undectectable acth no suppression acth supressed
adrenal tumor ectopic acth syndrome pituitary tumor (cushing disease)
133
hypotension, postural dizziness, syncope, hyponatremia and hyperkalemia, hyperpigmentation with increased ACTH and decreased aldosterone
addison disease or primary adrenal insufficiency, steroids, fluudrocortisone
134
fatigue, generalized weakness and weight loss with decreased ACTH and normal electrolytes
secondary adrenal insufficiency
135
hypernatremia and hypokalemia presents with hypertension, metabolic alkalosis
primary hyperaldosteronism
136
malignant hypertension with edema causes by renin secreting tumores
secondary hyperaldosteronism
137
causes of hyperaldosteronism include adrenal adenoma bilateral adrenal hyperplasim what are the treatments
1 - adrenalectomy | 2- spironolactone
138
wome get falactorrhea and amenorrhea in the absence of pregnancy with osteopenia
prolactinoma
139
men get decreased libido, CN III palsy, temporal field visual loss
prolactinoma, dopamine agonist like cabergoline or bromocriptine
140
DM and htn with increased hat and ring size
acromegaly, somatostatin analogues like octreotide or lanreotide
141
presents with HTN, headache, palpitations, and sweating
pheochromocytoma, phenoxybezamine followed by propranolol to prevent htn crisis measure 24 hour metanephrines
142
parathyroid hyperplasia, pancreastic islet cell tumor, pituitary adenoma
wermer syndrome or MEN 1
143
parathyroid hyperplasia, thyroid medullary cancer, pheochromocytoma
sipple syndrome or MEN 2A
144
thyroid medullary cancer, pheochromocytoma, mucocutaneous neuromas, marfan habitus
MEN 2B
145
esophageal issue associated with hiatal hernia
schatzki ring
146
dysphagia, cervical esophageal webs, and iron deficiency anemia
plummer vinson syndrome
147
cancer of esophagus at the top | what about the bottom
scc, smoking alcohol | adenocarcinoma, gerd
148
birds beak on barium swallow
achalasia
149
intermittent symtpoms with chest pain triggered by hot and cold liquids, corkscrew esphagus on barrium swallow
esophageal spasm
150
calcinosis cutis, raynaud syndrome, esophageal dysmotility, sclerodactyly, and telangiectasia
CREST syndrome
151
ulcers relieved by eating worse with eating
duodenal gastric triple therapy - amoxicillin, clarithromycin or metronidazole, PPI
152
abdominal pain, chronic diarrhea, and ulcer disease with elevated serum gastrin or secretin
zollinger ellison syndrome associated with MEN1
153
abdominal pain associated with altered bowel function with relief after defecation, pain is migaratory, variable and poorly localized
IBS, high fiber diet
154
diarrhea that severe and often bloody with fever at times
bacterial diarrhea, avoid abx unles invasive or c diff invasive give bactrim c diff give oral vanc
155
diarreha that friends and family have, no fever
viral diarrhea , loperamide
156
diarrhea outbreatk in day care travel
parasitic diarrhea giardia entamoeba give metronidazole
157
acute diarrhea duration | chronic
<2 weeks | >4-6 weeks
158
small bowel villous atrophy and crypt hypertropy resulting in malabsorption and iron deficiency anemia associated with dermatitis herpetiformis and gi malignancy
celiac sprue
159
tx or varacele bleed | prevention of vaacele bleed
ocretotide | propranolol
160
mid epigastric pain that radiates to the back and relieved by sitting forward. ocassionaly has jaundice and fever
pancreatitis
161
tx for necrotizing pancreatitis
imipenem or fluoroquinolone plus metronidazole
162
post prandial abdominal pain for 30 minutes with RUQ pain
biliary colic, rocephin plus metronidazole
163
fever, jaundice, and RUQ pain
cholangitis, ciprofloxacin
164
Fever, jaundice, RUQ pain, shock, and altered mental status aka reynolds pentad
suppurative cholangitis
165
high transaminase should make you think of
hepatitis
166
SAAG (serum ascities albumin gradiet) >1.1
portal htn --> cirrhosis, HF, budd chiari
167
SAAG <1.1
no HTN --> peritonitis, cancer, pancreatitis, trauma, nephroti csyndrome
168
tx of hepatic encephalopathy
rifaximin and lactulose, TIPS procedure predisoses you to this
169
SBP tx
rocephin or fluoroquinolone
170
fatigue, DM, arthritis, skin pigmentation, infertility, transaminitis, cardiomyopathy with increased FE saturation, ferritin and transferrin levels
hereditary hemochormotosis, phlebotomy
171
liver disease with neurophychiatric symtpoms and kayser fliesher rings. decreased copper and ceruloplasmin
wilson disease, penicillamine, trientine, oral zinc
172
young nonsmoker with panacinar emphysema
alpha 1 antitrypsin disorder, give antitrypsin and liver transplant
173
transamintis with ana, asmam, lkma and igG
autoimmune hepatitis, steroids and azathioprine
174
fatigue, pruritic, jaundice, fat malabsorption, osteoporosis
primary biliary chirrosis, ursodeoxycholic acid, cholestyramine, fat soluble vitamins
175
fatigue, pruritus, RUQ pain, ana, anti smooth muscle antibody, p-anca, associated with gi maligancy
primary sclerosisng cholangitis, ursodeoxycholic acid, cholestyramine, fat soluble vitamines
176
determines if antibodies are bound to the RBC membrane and is indicative of hemolytic anemia
direct coombs test
177
determines if there is antibodies to Rh factor in a mothers blood
indirect cooms test
178
can present with pica, low ferritin with wide RDW
iron deficiency anemia, iron supplementation
179
chronic hemolytic andemia and splenomegaly with increase in hemoglobin a and hemoglobin 4
hemoglobin H disease
180
growth retardation, heaptosplenomegaly, jaundice, and bony deformations as infant. normal RDW and basophilic stippling on smear
b- thalasemia major
181
causes HF, hepatic dysfunction, glucose intolerance, and secondary hypogonadism requiring chelation therarpy
iron overload secondary to repeat blood transfusions
182
always consider this cancer in microcytic anemia
colon cancer
183
low iron, low TIBC, normal transferrin with increased hepcidin
anemia of chronic disease, treat underlying issue
184
seen in mycoplasma and mono infection with sings of intravascular lysis, spherocytes and positive coombs test
cold agglutinin autoimmune hemolytic anemia
185
jaundice, spleenomegaly, spherocytes, cooms test positive, lysis in spleen
warm autoimmune hemolytic anemia
186
hemolysis during infection or sulfa drugs with bite cells
g6pd deficency
187
schistocytes and helmet cells caused by shearing through coagulated capillaryes
microangiopathic hemolytic anemia
188
hemolytic anemia, thrombocytopenia, and AKI with no neurological sign typically associated with gastroenteritis in children and shiga toxin
HUS
189
hemolytic anemia, thrombocytopenia, aki, fever, and neurological signs due to vWF and autoantibody against ADAMTs13
thrombotic thromcocytopenic purpura
190
chronic hemolysis caussing gallstones, poorly healy ulcers, jaundice, splenomegalsy, and heart failure, vaso-occulsive crisis
sickle cell anemia
191
sudden decrease in hemoglobin and reticulocyte cound caused by parvovirus b19
aplastic crisis, transfuse
192
fever, chest pain, cough, wheezing, tachypnea, new pulmonary infiltrate on CXR in sickle cell patinet
acute chest syndrome, oxygen, transfusion, rocephin, erythromycin
193
defect in ankryin or spectrin, speelomegaly, incresed RDW and MCHC, jaundice, confirmed by osmotic fragility test and howell jolly bodies
hereditary spherocytosis, vacinate against encapuslated organisms
194
shortness of breath with normal CXR, dizziness, confusion, headache, and seizures after exposure to benzocaine, dapsone, sulfa
methemoglobinemia, methylene blue
195
major difference in symptoms between folate and b12 deficiency
neurological symtpoms are found in b12 deficiency and b12 deficiency will have increased is methylmalonic acid
196
headache, blurry vision, fatigue, itching after a hot shower, Jak2 mutation
polycythemia vera, phlebotomy
197
visual complaints, headaches, or erythromelalgia (pain in hands and feet)
essential thrombocytosis, hydroxyurea
198
fever, sweats, weight loss, and hepatosplenomegaly, dry tap
primary myelofibrosis, transfusion, hydroxyurea, and splencetomy
199
plateletes <90,000
thrombocytopenia
200
eleveted PT or PTT
coagulopathy, give FFP to normalize
201
petechiae is a sign of
platelet deficiency
202
cavity or joint bleeding is a sign of
clotting factor deficiency
203
petechiae and easy brusising with igG antibodies
idiopathic throbocytopenic purpura (ITP) aka autoimmune thrombocytopenia, steroids
204
petechiae and easy brusing after heparin
HIT, platelet factor 4 antibodies found on serotonin release assay
205
recurrent spontaneous bleeding with increased PTT
intrinsic pathway likely hemophilia A (8) or hemophilia B (9)
206
recurrent sponteneous bleeding with inceased PT
extrinsic pathyway factor 7 disease
207
increased in both PTT and PT with recurrent sponteneous bleeding
common pathway factor 5, 10, 2
208
mucocutaneous bleeds, increased bleeding time, joint bleeds due to inability to form hemostatic plug
von Willebrand Disease, desmopressin (antidiuretic hormone)
209
mutation that disrupts activated protein C with slows the breakdown of factor 5 to 8
factor 5 leiden
210
issue with mutation that stabilized and increased prothrombin
prothrombin g20210a
211
warfrin is a resk of skin necrosis with this
protein c or s deficiency
212
inability to inhitib thromin and factor 10 resulting in heparin resistance
anti-thrombin II deficiency
213
found in any thrombosis and >3 miscarriages before 10 weeks or 1 after 10 weeks with postive anticardiolipin or lupus anticoagulant
antiphospholipid syndrome
214
fever, chills, and malaise after blood product
febrile reaction, leukocyte reduced RBC
215
fever, chills, pain, hypotension, flushing after blood produce due to ABO incompatibility
acute hemolytic reaction, supportive plus furosemide
216
jaundice, anemia, hemoglobinuria, fever
delayed hemolytic reaction, tylenol for fever
217
urticaria, itching, fives after blood product
allergic reaction, benadryl
218
shortness of breath, hypoxemia, bilateral chest infiltrates, 1-6 hours post transfusuion, ARDS
TRALI , ventilation support
219
shortness of breath, edema, fluid overload
TACO, furosemide
220
myeloblast and lymphoblast overgrowth, what is it called if this is <20 %
acute leukemia, meylodysplastic syndrome
221
overgrowth of metamyelocytes and lymphocytes
chronic leukemia
222
overgrowth of any lymphocyte, b cell is generally more than T cell
lymphoma
223
viral like syndrome with bone pain, pallor, petechiae, adenopathy, testicular and CNS involvement, anterior mediastinal mass typically in children with down syndrome
acute lymphocytic leukemia
224
fever, brusising, fatuge, infection, gingival hyperplasica, seen in people with previous chemo or radiation, increased urice acide, auer rods
acute myelogenous leukemia 15:17 gene translocation, 7+3 anthracycline based chemo or in AML M3 given all trans retinoic acide
225
lymphagenopathy and hepatosplenomegally often incidental finding on CBC, smudge cells on smeart, cyclin d1, CD5 and 23+. can be associated with ITP
chronic lymphocytic leukemia or mantle cell lymphoma t:11-14 translocation, fludarabine based regimen
226
b symptoms but in blastic phase has bone pain, bleeding, purpura, splenomegaly with CD11, trap and CD103, cbc shows 150000 wbc
chronic myelogenous leukemia , hairy cell leukemia has all the postiive cd things, philadelphia chromosome bcr-abl gene t9:22 give imatinib
227
cervical or mediastinal lymphadenopathy with b symptoms. has reed sternberg cells, mediastinal mass, contiguous speread
hodgkin lymphoma, ABVD adriamycin (doxorubicin), bleomycin, vinblastine, cacarbazine
228
assoicated with EVC, HTLV, MALToma, b symptoms, non-continguous spread
non-hodgkin lymphoma, r-chop which is rituximab, cyclophosphamide, doxorubicin, vincristine, presdnisone
229
occurs afte radiation resulting in hyperkalemia, hyperphosphatemia, hyperuricemia, hypocalcemia, leading to renal failure, gout, and stones
tumor lysis syndrome, hydration, allopurinol
230
CRAB, hypercalcemia, renal failure, anemia, bone lesions
multiple myeloma, bortezomib or lenalidomide
231
low plasma cells, low M protein, no crab symtpoms
MGUS
232
difference between smoldering myeloma and multiple myeloma
CRAB symptoms
233
bone pain, abdominal pain, kidney stones, delerium, fatiuge, bone lesions, decreased urine output
multiple myeloma
234
ductal carcinoma in situ or infavsive cancer of the nipple with unilateral itching, burning, and nipple erosion
paget disease
235
cancer treatment premenopausal postmenopausal her2-neu
tamoxifen and raloxefene anastrozole traztuzumab/herceptin
236
chornic cough, hemoptysis, weight loss, or postobstructive pneumonia in smoker, , radon, or asbestos
lung cancer
237
shouder pain, miosis, ptosis, anhidrosis and lower brachial pexopathy
pancoast syndrome
238
lung cancer in periphery
adenocarcinoma
239
lung cancer in central area
squamous cell
240
paraneoplastic syndromes of lung cancer
``` CLASH carcinoid -small cell lambert eaton - small cell ACTH - small cell SIADH - small cell hypercalcemia - squamous cell ```
241
painless jaundice, palpable gallbladder, migratory thrombophlebitis, venous thrombosis, b symptoms, abdominal and lumbar back pain, DM new onset
pancreatic cancer, whipple
242
admonimal pain with transamonitis and increase bilirubin
hepatocellular cancer
243
flushing, abdominal pain, diarrhea, and new tricuspid regurgitation
carcinoid tumors (increased seritonin or chromogrann A), give octreotide
244
hypoglycemia that is recurrent with relief on glucose adminsitration
insulinoma
245
profuse watery diarrhea that causes hypokalemia
VIPoma
246
persistent hyperglycemia with necrolytic erythema
glucagonoma
247
gross painless hematuria
bladder cancer
248
urinary frequency, anemia, hematuria, low back pain
prostate cancer
249
testicular cancer difference between seminoma and nonseminoma
seminoma has a normal a-fetoprotein, nonseminoma has increased alphfetoprotein
250
heamturia, flank pain, mass, b symptoms, paraneoplastic effects (erythrocytosis, hypercalcemia)
renal cell carcinoma vegf tyrosine kinase inhibitors pazopanib nivolumab, atezolizumab rapamycin inhibitor everolimus
251
menorrhagia, postcoital bleeding, pelvic pain, vaginal discharge
cervical cancer
252
progressive headache or focal neurologic deficit, spacsitc paresis, urinary incontinence, seizure
meningioma, resection
253
headache, wakes patient form sleep, vomiting, worse with valsalva, butterfly lesion
glioblastoma multiforme, resection
254
ca125
ovarian cancer
255
ca15-3
breast
256
ca19-9
pancrestic
257
CEA
GI cancer, colon
258
AFP
liver, yolk sac (testicular) cancer
259
hCG
choriocarcinoma
260
PSA
prostate cancer
261
LDH
lymphoma
262
calcitonin
medullary thyroid cancer
263
chromogranin A
carcinoid
264
b2 microglobulain
multiple myeloma
265
drug causes dilated cardiomyopathy
doxorubicin
266
drug causes renal and ostotoxiciy with neuropath
cisplatin
267
drug cuases hemorrhagic cystitis
cyclophosphamide
268
drug causes myelosuprression resulting in pancytopenia and needs folate supplementation with what
methotrexate, leucovorin
269
causes restrictive cardiomyopathy in cancer patients
radation
270
causes extrapyramidal symptoms
metoclopramide
271
MRSA coverage
bactrim or doxy or clindamycin, or vancomycin
272
well demarcated, edematous area of erythema of the face
erysipelas, PCN, keflex, bactrim
273
orbital infection with erythema and pain
preseptal cellulitis, treat like normal cellulits
274
orbital infection iwth oculomotro dysfunction, proptosis, chemosis, worse pain with movement, decreased visual acuity
septal cellulits, vanc and ceftriaxone
275
vizarre behavior, speech disorders, olfactory hallucinations or acute hearing impairment, MRI shows lesions of temporal lobes
HSV encephalitis, acyclovir
276
fever with altered mental statues in season change, extrapyramidal symtpoms, flaccid paralisys, IgM antibody
west nile encephalitis, supportive care
277
what do you have to add for coverage in people with meningitis who are over 50? what about if you suspect s pneumoniae
ampicillin for listeria | dexamethasone
278
tap shows PMNs which elevated opening pressure
bacterial meningitis give ceftriaxone due to increased neuro penetration
279
tap is normal
viral meningtisi
280
tap is just a little off
TB
281
pseudomonas treatment
ciprofloxacin
282
unilateral hearting loss and ear pain with lack of ormal light relex and is bulging
otitis media, amoxicillin
283
painful ear with foul smelling drainage
otitis externa, ofloxacin
284
fever, arthritis, carditis, chorea, rash
rheumatic fever, strep throat treatment is penicillin
285
trest strep throat to prevent what
rheumatic fever, can still get glomerulonephritis
286
acute fever, productive cought, dyspnea, pleuritic chest pian
pna, dont forget curb 65
287
low grade fever, nonproductive cough, myalgia
walking pneumonia
288
smoker with pna, diarrhea, hyponatremia and elevated lactate dehydrogenase
legionella
289
dysphagia, right lower infiltrate 1-5 days after event
aspiration PNA, clinda or augmentin
290
decreased LOC, symptoms 2-5 hours after aspiration, infiltrates everywhere
aspiration pneumonitis , supportive care
291
PCP tx
bacrim
292
cough +/- sputum production, dyspnea, fever, chills with no infiltrate. Cough >5 days
bronchitis, supportive care
293
TB treatiment
``` RIPE rifampin isoniazide pyrazinamide ethambutol these casue neuropathy and hepatitis ```
294
fever, chills, dysruia, cloudy urine, obstructive urine symptoms
prostatisis, fluoroquinolone or zosyn
295
painless, indurated, superfuical ulcerations
syphilis, doxycycline 14 days
296
chlamydia tx
azithromycin
297
gonorrhea tx
ceftiaxone
298
what does azt cause tenofovir? efavirenze
bone marrow supression renal toxicity CNS toxicity
299
prevention of malria
chloroquine --> mefloquine | daily doxy or atovaquone for short trip
300
HIV infection prophylaxsis
bactrim
301
blood in stool, fever, abdominal pain
infectious diarrhea, fluoroquinolon or azithromycin other than in EHEC this will cause hemolytic uremic syndrome
302
causes of bloody diarrhea
``` YEESSC yersinia ecoli entamoeba shigella salmonella campylobacter ```
303
presents after antimicrobial use, PPI with abdominal pain, diarrhea, nausea, vomiting, and ttp
needs CT for toxic megacolon workup. oral vanc is tx
304
aedes mosquitio, fever, polyarthralgia, maculopapular rash
chikungunya , supportive
305
anopheles mosquito causes jaundice, anemia, transminitis, thrombocytopenia, cyclical fver
malaria
306
fecal -oral route causing diarrhea, hepatosplenomegaly, rose sports
typhoid fever, fluoroquinolones
307
aedes mosquito, bone break fever, maculopapular rash, thrombocytopenia, hemorrhage
dengue fever, supportive
308
temperature >101.3F of sustained >100.4F for >1 hour in (ANC = PMN + bands <500) elderly people on chronic steroids my not mount fever
neutropenic fever pseudomonas - cefepime or carbapenem if not improved in 4-7 days consider fungus start amphotericin B, micafungin, or voriconazole
309
what do you not perform on neutropenic fever
rectal exam
310
erythema migrans, arthralgia, myalgia, myocarditis with av block, bell palsy, ixodes deer tic
lyme disease give doxy >9 amoxicillin <9 or pregnancy ceftriaxone if cardiac or neurologic symtpoms present
311
rash on plams and soles that spread to trunk, hyponatremia, transaminitis
rocy mountain spotted fever, doxy
312
cotransmitted with lyme disease, nonspecific symptoms
human monocytic ehrlichiosis, doxy
313
hemolytic anemia with maltese cross formation
babesiosis clindamycin and quinine or atovaquone and azithromycin
314
encapsulated yeast from pigeon droppings, silver stain, india ink show halo and capsul
cyptococcosis, fluconazole
315
narrow based budding yeast, bat or bird guano, ohio-mississippi river valley, flu like illness, palatal ulcerations, bone marrow suppresion
itraconazole if sever amphotericin
316
spherules with endospores, arizone or san joaquin valley, pna with dry cough and fever on silver stain
coccidiomycosis, fluconazole or itraconazole
317
broad based budding yeast, great lakes, ohio mississippi river valleys, PNA, verrucous rash, subcutaneous nodues, osteomyelitis, lytic leasion
blastomycosis itraconazole, amphotericin
318
mold, sepatted branched hyphae. fever, pleuritic chest pain, hemoptysis
aspergillosis, voriconazole
319
medications associated with SLE
``` SHIPP EM sulfa hydralazine isoniazid phenytoin procainamide interacept minocyline ```
320
noninfectious, granular, pea sized masses near the edge of a valve or valve ring
libman sacks endocarditis or verrucous endocarditis
321
needed for SLE diagnosis
``` 4 of 11 Dopamine rash Discoid rash oral ulcers photosensitive rash arthritis malar rash immuno criteria + anti dsDNA or antiSM neurologic symptoms renal disease ANA+ serositis hematologic disorder ```
322
highly specific for lupus
anti dsDNA and Anti Sm
323
seein in drug related lupus
Antihistone antibodies
324
boutonniere and swan neck deformities with anti CCP, long morning stiffness that improves with activity
RA, nsaids, sulfasalazine, hydroxychloroquine, methotrexate, infliximab, etanercept
325
joint stiffness, cartilage hypertrophy, morning stiffness for less than 30 minutes that worsens with activity, heberden nodes and bouchard nodes
osteoarthritis, weight loss, PT, NSAIDs
326
calcium pyrophosphate crystal with positive birefringent rhomboid crystal
pseudogout
327
needle shaped, negatively birefringent yellow crystals
gout, acute indomethasine, steroids, colchicine chronic - allopurinol
328
``` tap based on WBC <200 <3000 <50,000 >50,000 bloody ```
``` normal noninflammatory inflammatory infectious bloody ```
329
up going babinski sign is a ?
upper motor neuron sign
330
bowel and bladder incontinence/retention with saddle anesthesia
cauda equina syndrome, surgery
331
lower back pain with worsens with standing and walking but improves with sitting or leaning forward, easier to walk uphill rather than down
neurgenic claudication from degenerative disk disease
332
young man with chronic LBP that is worse in the morning with anterior uveities and HLA B27
ankylosing spondylitis, anti TNF inhibitors
333
deltoid and biceps with anterior shoulder sensation deficit and decreased biceps reflex
C5
334
biceps and wrist extensiors with decreased brachioradialis and decreased biceps and triceps reflex
C6
335
affects tricpes, wrist flexors, and finger extensors, decreased sensation of triceps with decreased reflex
C7
336
problems with rising from a chair and heel walking with decreased sensation over knee and medial calf causing decreased knee jerk reflex
L3-4
337
problems with heel walking, extension of big toe, or dorsiflexion of ankle
L5
338
problems with toe walking or plantar flexing the ankle, decreased ankle jerk reflex
S1
339
progressive stiffness of the spine, uveitis, aortitis, psoriasis and IBD
anylosing spondylitis, nsaids, TNF inhibitors
340
joint pain, nail pitting, sacrolitis and spondylitis
psoriatic arthtis
341
aka reiter syndrome
reactive arthritis
342
new headache and scalp tenderness with pain on combing the hair, temporal tenderness, jaw claudication and monocular blindness
temporal arteritis, prednisone and eye eval
343
fatigue, weight loss, fever, mononeuritis multiplex seen in HEP B and C
polyarteritis nodosa, glucocorticoid , cyclophasphamide and rituximab
344
bilateral aching and morning stiffness lasting >30 minutes for at leasdt 2 weeks, pain of shoulder and pelvic girdle, fever, malaise, weight loss , difficulty getting out of the chair or lifitng arms above head, no weakness
polymyalgia rheumatica, prednisone
345
myalgia, insomnia, weakness, fatiuge, trigger pints, depression, anxiety , IBS with no swelling
fibromyalgia, gabapentin, SSRI
346
proximal mucle weakness without pain
polymyalgia rheumatica
347
proximal muscle weakness with pain
ploymyositis
348
progressive proximal muscle weakness , pain, difficulty rising form chair, trouble swallowing, difficulty speaking and breathing with increased CK and aldolase. muscle inflammation and fiber necrosis
polymyositis, corticosteroids, methotrexate or azathioprine
349
heliotropic rash, gottron papules associated with internal malignancy
dermatomyositis
350
symmetirc thickening of skin, tight face, telangiectasias
scleroderma
351
form of scleroderm assocaited with raynaud, barret esophagus, reflux, pulmonary htn and anticentromere antibody
crest syndrome
352
anti SCL 70 antibody associated with pulmonary interstitial fibrosis
diffuse scleroderma
353
dysmorphin RBCs and RBC cast on UA
acute glomerulonephritis (post strep or IgA nephropathy)
354
eosinophils and WBC cast
Acute interstitial nephritis ( meds)
355
pigmented granular "muddy brown" cast
acute tubular necrosis
356
issues with sodium cause
nausea/vomiting, fatigue, seizure
357
issues with potassium cause
muscle weakness and paralysis
358
correcting hypernatremia to fast causes
cerebral edema
359
correcting hyponatremia to quicly causes
osmotic demylination syndrome
360
tx for hypervolemic hyponatremia
loop diuretic
361
tx for euvolemic hyponatremia
fluid restriction 1L/day, loop diuretic, high salt diet
362
tx for hypovolemic hyponatremia
NS
363
two causes for euvolemic hypernatremia are
central DI, desmopressing | nephrogenic DI, remove medication
364
causes for hypovolemic hypernatremia
dehydration
365
causes for hypervolemic hypernatremia
iatrogenic or hyperaldosteronism
366
vomiting associated with
hypokalemic hypochloremic metabolic alkalosis
367
24 hour urine K >30 acidosis alkalosis
RTA I or II, DKA | or hyperaldosteronism, sushing, bartter, gitelmann
368
24 hourr urine K <30 acidosis alkalosis
laxitive abuse or vomiting/NG suction
369
acidosis causes what in relationship to potassium
hyperkalemia
370
alkalosis causes waht in relationship to potassium
hypokalemia
371
loss of glomerular basement membrane funtion causing large plasma protein loss into urine
nephrotic syndrome, ACE or ARB, loop diuretic, statin,
372
inflammation of the glomerulus causing a loss of RBC and large plasma proteins in the urine
nephritic syndrome, treat underlying condition
373
large protein loss with podocyte epithelial foot process effacement in young children
minimal change disease, steroids and cyclophosphamide
374
large protein loss with glomerular sclerosis associated with HIV and heroin use
focal segmental glomerulosclerosis, steroids then cyclosporine
375
large protein loss, capillary wall thickening, spike and dome appearance, subepithelia deposists associated with HBV
membranous nephropathy, steroids pluse cyclophosphamide
376
large protein loss, subendothelial deposists associated with HCV and SLE
membranoproliferative glomerulonephritis, antiviral therapy
377
large protein loss with nodular glomerulosclerosis (kimmelstiel wilson lesions)
diabetic nephropathy, glucose control , ACE/ARB
378
large protein loss in african americans with SLE
lupis nephritis, mycophenolate
379
large protein loss with apple green birefringence seen in multiple myeloma
renal amyloidosis, steroids plus melphalan
380
purpura and hemoptysis with blood and protein loss on UA with necrotizing vasculitis
microscopic polyangitis, steroids plus cyclophosphamide.rituximab
381
oral ulcers, saddle nose, necrotizing vasculitis with granuloma formation, blood and protein on UA
granulomatosis with polyangitis, steroids and cyclophsphamide/rituximab
382
asthma, nasal polyps, blood and protein on UA, necrotizing vasculitis with polyangitis
eosinophilic granulomatosis with polyangitis
383
pulmonary hemorrhage, hematuria and proteinuria with IgG depositis along GBM with crescentic glomerulonephritis, +anti GBM
goodpasture syndrome, steroids plus cyclophosphamide, plus plasma exchange
384
hematuria 3 weeks following URI or skin infection, crescentic glomerulonephritis, +ASO antibody
poststreptococcal glomerulonephtitis, supportive care
385
hematuria 1-2 days following URI or GI infections with mesangial IGA immune deposition
IgA nephropathy, supportive, ACE
386
sensorineural hearing loss , ocular defects, hematuria and proteinuria, GBM thickening with tubular foam cells
alport syndrome, ACE or ARB
387
envelope shaped crystals in urine
calcium oxalate stones
388
coffin lid shaped crystals
struvite stone, uti prevention
389
diamond shaped crystals
uric acid, alkalinize urine, xanthine oxidase inhibitor
390
hexagonal shaped crystals
cystine, penicillamine, alkalinize urine
391
RTA with Hydrogen hypersecretion
type 1 (distal), give bicarb
392
RTA with difficulty in HCO reabsorption
type 2 (proximal), give bicarb
393
RTA with aldosterone deficiency or esistance (high potassium)
type 4 depends on causative agent
394
if you give bisphosphonates to people with CKD what will happen
osteomalacia
395
increased in calcium, soft tissue calcinonis with necrosis, intractible bone pain in CKD patient
metabolic bonde disease , parathyroidectomy
396
what happeds to CKD patients over time in regards to Ca? | which causes what? and this leads to autonomous PTH secreation with increased Calcium which is termed ?
decreased elevated PTH causing secondary hyperparathyroidism over time leads to tertiary hyperparathyroidism and metabolic bone disease
397
in upper motor lesions everything is ____
up except fasciculations are absent. LMN lesions are opposite
398
contralateral sensory deficits with hemineglect
right MCA stroke
399
contralateral sensory deficiets with language deficits
left MCA stroke
400
aphasia where comprehension is intact but they have nonfluenct speech
broca aphasia (expressive)
401
poor comprehension, word salad
wernicke aphasia (receptive)
402
contralateral leg weakness
ACA stroke
403
homonymous hemianopia with macular sparing
PCA stroke
404
nystagmus, horner syndrome, loss of pain and temperature on ipsilateral face and contralateral body
posterior inferior cerebellar artery (medulla) Wallenberg syndrome
405
ipsilateral limb ataxia
anterior inferior cerebellar artery (pons)
406
ipsilateral cranial nerve II palsy and contralateral arm and leg weakness
Posterior cerebral artery (midbrain) Weber syndrome
407
pure motor stroke
internal capsule
408
pure sensory stroke
thalmus
409
locked in syndrome
basilar artery (pons)
410
lucid interval with biconvex hyperdensity
epidural hematoma
411
headache, altered mental status, cresentric that crosses suture lines
subdural hematoma, bridging veins
412
ipsilateral miosis (contriction) ipsilateral ptosis (eyelid droop), and ipsilateral anhidrosis of face
horner syndrome
413
bandlike headache
tension, NSAIDS
414
unilateral throbbing pain, aura, scotoma, famililal
migraine prophylaxis: amitriptyline, propranolol abortive: triptain, nsaid severe: IV hydration, antiemetics, antihistamine, steroid, ergotamine
415
breig, severe, unilateral, periorbital, same time each day, ipsilateral lacrimation, horner syndrome,
cluster, oxygen or triptan | prevention - verapamil
416
overweight female with elevated opening pressure and evidence of papilledema
pseudotumor cerebri, weight loss, acetazolamide
417
mimics migraine with family history of sudden stroke after symptoms
aneurysm
418
progressively worse headache particularly in morning, seizure, or personality changes
tumor headache
419
progressive jerking that spreads form one limb to the next on ipsilateral side
jacksonian march seizure
420
intermittent , positional, tinnitus, hearing loss, nystagmus is rotary, fixation of gase stops vertigo
peripheral vertigo, epley maneuver for BPPV then do PT or give scopolamine
421
neurologic signs, nystagmus changes direction with gaze, vertical nystagmus is highly specific
central vertigo, MRI
422
``` peripheral vertigo that lasts seconds min-hr >1 day variable ```
BPPV TIA or meniere disease , MRI vestibular neuronitis unknown, MRI
423
bilateral pain, numbness, and weakness below level of a lesion
spinal cord compression
424
neurologic signs, back pain, and fever,
epidural abscess, cephalosporin and vanc
425
pain relieved by bending over and improved when walking uphill, negative straight leg raise
spinal stenosis - nsaids, pt, steroids, lamincetomy
426
weakness, numbness, and autonomic dysfunciton below level of lesion
transverse myelitis, MRI spine, high dose glucocorticoids
427
loss of pain and temperature in cape distribution followed by weakness of the arms
central cord
428
ipsilateral weakness with loss of light touch and vibration with contralateral loss of pain and temperature sensation
brown sequard syndrome
429
motor paralysis and loss of pain below lesion
anterior cord syndrome
430
bilateral loss of light touch, vibration, proprioception seen with b12 deficiency or tabes dorsalis
posterior cord syndrome
431
progressive muscular weakness and wsasting with combination of upper and lower motor signs
ALS, supportive with riluzole and edaravone
432
extenign and rotating neck to the side of pain and applying prssure reproduces symptooms and straight leg raise is postive
herniated disk, NSAIDS, steroids, pt, surgery
433
loss of forehead and brow movements, inability to close eyes and drooping of eyelids, loss of nasolabial folds and drooping of lower lip
peripheral facial palsy CN 7
434
loss of nasolabial folds and drooping of lower lip with preservation of forehead and brow movement
cental facial palsy
435
disorder of antibodies agianst post synaptic ACh receptors presents with worsening symptoms with physical acitivy, assocaited with thymoma, positive edrophonium test
myasthenia gravis, pyridostigmine, azathioprine single fiber EMG shows jitter
436
ptosis and diplopia toward end of the day
ocular myasthenia
437
respiratory muscle fatigability leading to respiratory failure
myasthenic crisis, plasmapheresis and/or IVIG
438
antibody to presyaptic calcium channel receptors, symptoms improve with acitivy, small cell lung cancer association
lambert eaton syndrome
439
toe walking, waddling gait, inability to run or climb stairs, death due to dilated cardiomyopathy, gower sign present
duchenne muscular dystropy, x-linked dystrophin gene, give prednisone
440
``` present with traped symptoms tremor - pill rolling rigidity (cogwheel) akinesia postural instability masked face ```
parkinson (substantia nigra) carbidopa levodopa benztropine for tremor
441
``` progressive involuntary movements, demential, and psychosis choreiform movements eye slowing hyperreflexia dementia, depression ```
huntington disease caudate and putamen atrophy CAG repeats ``` symptomatic treatment SSRI benzos carbidopa/levodopa second generation antipsychotic ```
442
lhermitte sign (shooting pain down spine with flexion), optic neuritis (decreased visual acuity, pain with eye movements), marcus gunn pupil, internuclear ophthalmoplegia, mri shows dawson fingers
multiple sclerosis, copaxone or interferon second line dimethyl fumarate exacerbation - steroids
443
decreased depth perception, loss of short term memory, decresaed speech, personality changes, depression
dementia
444
b-amyloid plaques and neurofibrillary tangles
alzheimer disease, donepezil, rivastigmine, memantine
445
socially inappropriate, poor decisions, pick bodies
frontotemporal dementia
446
parkinsonian features, visual hallucinations, REM sleep disorder, mood disturbance
lewy body dementia
447
acute onset of dementia accociated with myoclonic jerks and periodic sharp waves on EEG,
creutzfeldt-jakob disease
448
stepwise worsening of symptoms with lacunar strokes
vascular dementia
449
ataxia, ophthalmoplegia, and confusion
wernickey encephalopathy give thiamine before glucose
450
impaired short term memory loss, confabulation
korsakoff psychosis
451
delivery >37 weeks
full term
452
between 20 weeks and 36w6d
preterm
453
pregnancy ending before 20 weeks
abortion
454
weight gain during pregnancy underweight normal obese
``` 28-40 25-35 11-20 additional intake is only 300 cal per day 500 while breast feeding ```
455
pregnancy screening | 10-14 weeks
non-invasive prenatal testing if positiv due amniocentesis which carries risk of hemorrhage and fetal loss
456
what pregnancy test is done at 24-28 weeks
glucose challenge
457
what do mothers get at 28 weeks
rhogam if Rh negative
458
what test at 35-37 weeks
GBS
459
increased maternal serum alpha fetal protein
neural tube defect
460
increased inhibin A
trisomy 21
461
everything is decreased
trisomy 18
462
NST shows absent variability minimal moderate
acidemia sleep or drug normal
463
non reactive NST meaning no or only 1 acceleration in 20 minute period means what
have to do biophysical profile or contraction stress test
464
``` biophysical profile (test the baby man) tone breathing movement amniotic fluid nst either get a 2 or 0 in each category ```
>8 good | <6 deliver
465
``` painful contractions iwth cervical change slow changed up to 20 hours rapid change >1 cm/hr starting at 6 cm 10 cm to delivery delivery to placenta ```
``` labor latent labor active labor 2nd stage of labor 3rd stage of labor ```
466
variable decel indicates what early late
cord compression head compression fetal hypoxia and uteroplacental insufficieny
467
fetal heart tracing 110-160, moderate variability, no decelerations absent variability with late or variable decelerations, fetal bradycardia <110
category 1, normal | category 3, delivery
468
vitamin A and derivatives like isotretinoin cause
heart and great vessel defects, craniofacial dysmorphism, deafness
469
tetracyline causes
tooth discoloration
470
quinolones cause
cartilage damage
471
streptomycin causes
ototoxicity
472
bactrim causes
neural tube defects
473
lithium causes
ebstien anomaly
474
methylene blue causes
jejunal and ileal atresia
475
ssri cause
pulmonary HTN
476
NSAIDS cause
oligohydramnios, closure of ductus arteriosus
477
ACE cause
renal damage and oligodydramnios
478
methimazole causes
aplasia cutis
479
valproic acid causes
craniofacial defects
480
phenytoin causes
dysmorphic faces, microcephaly, nail and finger hypoplasia
481
carbamazepine causes
craniofacial defects
482
phenobarbitol causes
cleft palate and cardiac defects
483
warfarin causes
fetal nasal hypoplasia
484
rupture of membranes before onset of labor
premature rupture of membranes, if this occures before 37 weeks is preterm premature rupture of membranes
485
GBS unknow patients with fever and prolonged rupture of membranes
give PCN or ampicillin
486
labor at 34-36 weeks
give betamethasone
487
labor at 24-34 weeks
give betamethasone, magnesium, ampicillina nd erythromycin
488
maternal fever, leukocytosis, fetal tachycardia, purulent amniotic fluid
chorioamnionitis, ampicillin and gentamicin
489
what do you give prior to doing external cephalic version
rhogam
490
forearm supinated, wrist extension, MCP extended, DIP flexed
klumpke palsy (claw hand)
491
shoulder internal rotation, elbow extended, forearm pronation, wrist flextion
erb-duehenne palsy (waiter tip)
492
gestational HTN pluse proteinuria
preeclampsia
493
preeclampsia with elevated creatinine, transammonities, thrombocytopenia, pulmonary edema, headache
preeclampsia with severe features
494
preeclampsia plus seizure
eclampsia
495
increased LDH, uric acid, decreased hemoglobin, transammonitis, throbocytopenia
HELLP syndrome
496
hyperthyroid tx in pregnancy
1st trimester PTU | 2-3rd methimazole
497
failure to lactate after postpartum hemorrhage with lethargy, anorexia, weight loss, amenorrhea, and loss of sexual hair
sheehan syndrome (postpartum hypopituitarism) corticosteroids, levothyroxine, estrogen, and progesterone
498
mastitis treatmetn
dicloxacillin or erythromycin
499
soft, enlarged boddy uterus during postpartum hemorrhage
uterine atony, massage, oxytocin infusion methylergonovine
500
difference between postpartum blues depression psychosis
mild resolves in 2 weeks MDD within 12 months of birth psychotic symptoms within 2 weeks SSRI
501
postpartum fever with fundal tenderness within 24 hours of delivery
endometritis
502
``` pregnant closed cervix with bleeding dilated no products expelled cervix closed with no HR open with some products of conception closed with empty uterus ```
``` threatened abortion inevitable abortion missed abortion incompleted abortion complete abortion ```
503
fever, severe abdominal and cervical tenderness, purulent and malodorous discharge on exam, products of conception visualized
septic abortion
504
abdominal pain, persitent vaginal bleeding, hx HTN, trauma, tobacco, or cocaine use in pregnant pt
placental abruption, mild bed rest, severe deliver
505
painless vaginal bleeding particularly in 3rd trimester
placenta previa, c-section
506
severe abdominal pain during labor, abdomen change in shate, loss of fetal station
uterine rupture, c-section
507
abnormal uterine bleeding causes
``` palm coein polyps adenomyosis leiomyomas malignancies (check biopsy anyone >45) coagulopathy ovulatory dysfunciton endometrial iatrogenic not classified ``` tx NSAIDS, ocp, iud, txa, artery embolization and hysterectomy
508
absence of menses by age 15 or absence of menses within 5 years of breast development
primary amenorrhea
509
absence of menses for three cycles if previously regulaor for 6 months if irregular
secondary amenorrhea
510
for primary amenorrhea first check to see if they have secondary secual characteristics, if yes then is the uterus present? yes? no?
outflow obstruction either imperforate hyman or evalute for secondary amenorrhea no - karyotype analysis
511
primary amenorrhea with 46, xy
androgen insensitivity syndrome
512
primary amenorrhea with 46 xx
mullerian agenisis
513
primary amenorrhea with no sexual characteristics you need to measure FSH and LH if they are low if they are high
hypo-gonadotropic hypogondadism hypergonadotropic hypogonadism, do karyotype
514
hypergonadotropic hypogonadism 46, xy 46 , xx
either saywer syndorme or turner syndrome premature ovarian failure
515
pain with menstrual periods that requires medication and prevents normal activity with no clinically detectable pelvic pathology with detectable pelvic pathology
primary dysmenorrhea due to increased uterine prostaglandin production secondary dysmenorrhea due to endometriosis, adenomyosis, or leiomyomas
516
irregular menstrual bleeding, unwanted hair growth, acne, insulin resistance, weight gain with difficulty concieving
PCOS | DM tx, clomiphene / metformin, OCPS ro spinronolactone
517
cyclic pelvic pain, dysmenorrhea, dysparenunia, and infertility
endometriosis, gold standard is direct visualization | nsaids, ocp, removal of endometrial implants, lastly total abdominal hysterectomy
518
first trimester uterine bleeding with excessive nausea and vomiting 69, xxx or xxy with fetal parts 46 xx or xy without fetal parts
gestational trophoblastic disease partial mole complete mole d and c, serial b-hcg weekly until negative, then monthly for 6 months
519
most common cause of vaginal discharge in pediatric patients
retained foreign body
520
gray or white fishy discharge, clue cells, whiff test
BV, metronidazole
521
strawberry cervix, yellow, green, frothy
trichomonas, metronidazole x1 dose
522
tachydardia, fever, diffuse abdominal tenderness, CMT, chandelier sign
pelvic inflammatory disease cefoxitin and doxycycline or clinda and gent then transition to PO doxycycline 24 hours after clinical improvement treat for 14 days outpatient management is for 14 days as well
523
amenorrhea, abdominal pian, nausea, vomiting, adenexal mass or fullness can present with crashing patient positive bHCG
extopic pregnancy fetal heart motion can be seen 5-6 weeks into gestation unstable need surgery b-hcg <1500 with no visible baby repeat bhcg in 48 hours with repeat US in 1 week ``` ectopic medical -no fetal cardiac motion -bhcg <5000 -gestational sac <3.5cm and reliable follow up ``` dont forget rhogam
524
these are all contraindications to what pregnancy, migraines with aura, previous DVT, smokers >35, genital bleeding, estrogen neoplasms, HCC, liver dysfuntion, HTN
OCPs
525
cessation of menstruation for 12 consecutive months causes increased risk of osteoporosis and heart disease
menopause, suggest by incresae FSH
526
premature menopause occurs before age 40 and is often due to what
idopathic premature ovarian insufficiency
527
loss of urine with coughing, running, laughing, sneezing
stress incontinence (poor function of sphincter) kegel exercises, weight loss, pessaries, suburethral sling
528
loss of urine with urge to void due to involuntary detrusor muscle contration
urge incontinence, behavior modification, bladder training, anticholinergics, sacral neurostimulator
529
urgency to void with or without urge incontinence and often with nocturia and frequency due to involuntary detrusor mucle contraction
overactive bladder syndrome, behavior modification, bladder training, anticholinergics, sacral neurostimulator
530
bilateral breast discharge is concerning for what
prolactinoma
531
multifocal and bilateral nodulatiry with pain in breasts with premenstrual lumps
fibrocytic changes, OCPs
532
small , firm, unliateral, nontender mass that is freely movable and slow growing on breast
fibroadenoma, 30% with disappear on their own
533
blear, bloody, or discolored fluid form a single duct opening of breath
intraductal papilloma, drainage and exploration
534
seen in breastfeeding, hard, red, tender, swollen area
mastitis, continue breast feeding, NSAIDS and abx
535
mastitis with fluctuant mass
abscess
536
firm, tender, and ill definced with surrounding erythema related to trauma or ischemia of breast
fat necrosis, analgesia
537
used for anxiety, agitation, catatonia, alcohol withdrawl, insominal, seizure and muscle spams risk of respiratory depression, decreases carbamazepine and rifampin
benzodiazepines
538
nonbenzo used for insomnia
zolpidem
539
used for GAD in patients with history of substance abuse. dont use with MAOIs
buspirone
540
first line therapy for depression , OCD and anxiety disorders can increase warfarin levels and causes sexual dysfuntion
SSRI
541
antidepressants can provoke mania in patients with
undiagnosed bipolar disorder
542
first line therapy for depression and smoking cessation lowers seizure threshold
buproprion - dopamine and norepi reuptake inhibitor
543
used for MDD, GAD that causes HTN, insomnia and sexual dysfunction
venlafaxine, serotonin and norepi inhibition
544
alpha 2 antagonist that enhances norepi and serotonin causes weight gain
mirtazapine
545
serotonin antagonism that is used for insomnia and causes priapism
trazodone
546
used for chronic pain and migraines and neuropathic pain causes dry mouth, blurry vision, constipation, urinary retention, orthostatic hypotension and heart block reflected by prolonged PR and QRS interval
tricyclic antidepressant
547
second line agenst due to tyramine induced hypertensive crisis due to aged chees, chocolate, alcohol and pickled foods. causes serotonin syndrome if mixed with almost any other drug
MAOI (selegiline, phenylzine) fluoxetine takes 5 weeks to wash out
548
antipsychotic that is safe for acute mania or psychosis in pregnancy
haloperidol
549
used for psychotic disorders and acute agitation causes extrapyramidal symptoms from excessive cholinergic effect, hyperprolactinemia, NMS, arrhthmia, and wight gain
first generation typical antipsychotis (domapine receptor blocker)
550
antipsychoics used for only positive symptoms of psychosis associated with more extrapyramidal symptoms
haloperidol and fluphenazine (high potency agents)
551
antipsychoics used for sedation, associated with anticholinergic effecs and hypotension
lower potency agents like chlorpromazine
552
first line therapy for schizophrenia and tic disorders fewer extrapyramidal symptoms and anticholinergic effects but does cause metabolic syndrome, dry outh, blurry vision, urinary retension, QT prolongation
second generation atypical antipsychotics
553
second generation atypical antipsychotics used for treatment refractory psychosis causes sialorrhea (drooling), agranulocytosis, myocardiits, seizures
clozapine
554
involuntary muscle contraction or spasm (torticollis, oculogyric crisis)
acute dystonia, give benztropine (cogentin) or diphenhydramine
555
parkinsonism within weeks of starting anticholinergic
dyskinesia, benztropine or diphenhydramine
556
subjective restlessness
akathisia, benadryle or propranolol
557
oral-facial movmeents often irreversible
tardive dyskinesia
558
long term use of this drug causes hypothyroidsim, DI, nephrotoxicity
Lithium
559
used for long term maintenance or prophlaxiss of bipolar disorder and for both depression and mania causes thirst, polyuria, hypothyroidism
lithium
560
tremor, ataxia, vomithing, confusion, seizures, and arrhythmias. risk of ebstein anomaly
lithium toxicity
561
first line agent for acute mania and bipolar disorder. can cause pancreatitis, hepatotoxicity
valproic acid
562
secondy line agent for acute mania and bipolar disorder. causes hepatic toxicity, SIADH, bone marrow suppression
carbamazepine
563
CGG repeat disorder, long face, large body size, macro-orchidism. most common inheritied cause of intellectual disability
fragile x syndrome, SBT, risperidone and aripiprazole
564
x-linked genetic disorder that affects only girls, normal development until 18 months with development of especially language and motor skills, microcephaly, epilepsy
rett disorder, SBT, risperidone and aripiprazole
565
six or morth symptoms for 6 months of inattention, hyperacitivity in 2 or more settings
ADHD, stimulants and nonstimulant stimulants dont lead to substance abuse issues
566
multiple motor and vocal tics
tourette syndrome, CBT , haloperidol, pimozide
567
disorder of dopamine due to increased positive symptoms from limbic system and negative symptoms from frontal cortex, increased risk of substance abuse and suicide two or more positive or negative symptoms for at least 1 months and must result in impairment of functioning. must include delusions, hallucinations, or disorganized speech and must persist for at least 6 months
scizophrenia, antipsychotics
568
symptoms of schizophrnia less than 1 month
breif psychotic disorder
569
schizophrenia with symptoms of 1-6 months
schizophreniform disorder
570
mood symptoms but psychotic symptoms present for at least 2 weeks without a mood episode
schizoaffective disorder
571
SIG E CAPS | sleep, interest, guilt, energy, concentation, appetite, psychomotor issues, suicidal ideation
MDD | sertraline --> fluoxetine --> paroxetine --> venlafaxine --> buproprion
572
two symptoms of MDD, chornically depressed for 2 or more years
dysthmia
573
doesnt involve severe impairment, anhedonia, or suicidality lasting 2 months to 1 year, visual and auditory hallucinations are common and normal
bereavement
574
doesnt meet criteria for MDD but occures within 3 months of a stressor and lasts <6 months
adjustment disorde with depressed mood
575
used for psychotic or catatonic depression
ECT
576
``` digs far distractibility insomina grandiosity pessured speech flight of ideas psychomotor agitiation recklessness ```
bipolar disorder, manic episode
577
bipolar symptosm last for 4 days with no functional impairment
hypomania
578
periods of hypomanic symptoms over 2 or moe years that never meet biploar criteria or mdd
cyclothymic disorder
579
one manic episode determies diagnosis
bipolar I disorder
580
one hypomanic episode alternating with one MDD episode
Bipolar II disorder
581
tx of acute mania
lithium, antipsychotics, benzo, ECT
582
bipolar depression stabilizer
lithium or lamotrigine
583
persistent, excessive, or unrasonable fear or avoidance of an object or situation in relation to social performance
phobia, CBT, SSRI, benzo social anxiety disorder, propranolol
584
``` PANICS palpitations abdominal distress numbness intese fear of death choking, chills, chest pain sweating, shaking, sob ```
panic disorder | CBT and SSRI then do benzo
585
excessive and pervasive worry on most days for at least 6 months
GAD, venlafaxine
586
persistent, intrusive thoughts, impulses, or images that lead to anxiety and interfere with daily life
obsession
587
conscious , repetitive behaviors reactions to obessions
compulsions
588
difference between OCD and obsessive compulsive personality disorder
ocpd doesnt cause distess tx OCD with ssri
589
results from exposue to a traumatic event that involved actual or threatened death or serious injury, nightmares and flashbacks are common
PTSD, SSRI
590
PTSD symptoms <1 month and occur within 1 month of a trauma
acute stress disorder
591
emotional or behavior symptoms occuring within 3 months of stressor and lasting <6 months
adjustment disorder with anxiety
592
emotional or behavioral symptoms in response to an identifiable stressor occuring within 3 months of the stressor, distress out of proportion to stressor and resolves by 6 months
adjustment disorder, supportitve therapy, CBT
593
temporary amnesia from ones own identiy. they will come out of it living a new life and never remember the stressor or the new life
dissociative amnesia
594
symptoms are acoompanied by disproportionate thoughts, feelign, or behaviors regarding symptoms. pain or pain profile that is inconsistent with physiologic processes
somatic symptom disorder, psychotherapy and SSRI
595
preoccupation for >6 months with fear of having serious disease based on misinterpretation of symptoms
illness anxiety disorder, PT, psychotherapy, antidepressants
596
symptoms that ae not volitionally produced and cant be explained by a known organic etiology example is alterations in voluntary motor or sensory function
conversion disorder, reassurance, psychotherapy
597
symptoms are consciously produced but the reason may be unconscious. falsification of physical or psychological symptoms or inducitn injury or illness
factitious disorder
598
conciously producign illness for secondary reward
malingering
599
refusal to maintain normal body weight <85% ideal body weight, intense fear of weight gain, distorted body image. lanugo, dry skin, lethargy, bradycardia, hypotension, peripheral edema what are the two types
restricting type and binge-eating purging type anorexia nervosa amenorrhea is no longer required for diagnosis
600
normal weight or are overweight but engage in binge eating without self control with compensatory behavior to attempt to control weight poor dentition, enlarged parotid glands, dorsal hand surfaces, metabolic alkalosis
bulimia nervosa CBT
601
child has never achieved continence
primary enuresis
602
child achieves night tome continence for 6 months but then begins bedwetting again
secondary enuresis, behavioral therapy, desmopressin
603
difficulty falling or staying asleep associated with nonrestorative sleep 3+ times per week for 3 months
insomnia, CBT
604
excessive daytime sleepiness occuring 3x per month for 3+ months with hallucinations associated with sleep and decreased levels of hypocretin
narcolepsy, modafinil plus methylphenidate if needed
605
loss o fmuscle tone leading to collapse associated with strong emotions or excitement
cataplexy, SSRI
606
urge to move legs at night and relieved by movement associated with iron deficiency, uremia, DM, MS
restless leg syndrome
607
angry irritable mood with hostile and defiant attitude toward authority figures of >6 months
oppositional defiant disorder, parent manegement training, CBT
608
patietn repeatedly and significantly violates societal norms and the rights of others for 1 or more years
conduct disorder
609
disinhibition, slurred speech, ataxia, aggression
alcohol intoxication
610
euphoria, CNS depression, miosis, respiratory depression
opioid intoxication, naloxone
611
psychomotor agitation, tachycardia, mydriasis, fevr, HTN, paranoia, angina, sudden death
amphetamine overdose (cocaine), sedatives
612
aniety or deprrsion, delusions visual hallucinations, mydriasis
LSD, benzodiazepine
613
euphoria, slowed sense of time, increased appetite, dry mouth, conjunctival injection, anxiety paranoia
marijuana intoxication
614
respiratory depression, low safety margin
barbiturates OD
615
respiratory depression exacerbated with alcohol use
benzo OD
616
restlessness, insomnia, diuresisi, muscle twitchign, psychomotor aggitation
caffiene OD
617
restlessness, insomnia, anxiety
nicotine
618
tremor, tachycardia, diaphoresis, HTN, DT
alcohol withdrawal
619
anxiety, insomnia, anorexia, mydriasis, fever, goosebumps, stomach cramps, very concomfortable
opioid withdrawal
620
post use crash, nightmares, depression, severe craving
cocaine withdrawal
621
anxiety, seizures, life threatening cardiovascular collapse
barbiturate withdrawal
622
rebound anxiety, seizures, tremor, insomnia, hyperension, tachycardia
benzo withdrawal
623
headache, lethargy, depression, weight gain, irritability, craving
caffiene withdrawal / nicotine withdrawal
624
acute onset of lethargy, agitation, perception (hallucinations) altered cognition that wax and wane during the day
discontinue any meds that could cause that, frequent reorientation, haloperidol or risperdol
625
chronic degradation of the mind, alert, intact consciousness, disrupted memory, orientation, language
dementia
626
pt is distrustful and suspicious
paranoid personality
627
distant, isolated, detached
schizoid personality
628
odd behavior/appearance, magical thinking
schizotypal personality
629
unstable mood/relationships and feelings of emptiness, impulsive, high risk of suicide or self harm
borderline personality
630
excessively emotional and attention seeking, sexually provocative
historionic personality
631
grandiose, need admiration, sense of entitilement, lack empathy
narcissistic personality
632
violate the rights of others, social norms, and laws, develops from conduct diosrder
antisocial personality
633
preoccupided iwth perfectionism, order, control. inflexable morals and values
obessive compulsive personality
634
socialy inhibited, sensitive to rejection
avoidant personality
635
submissive, clingiy, need to be taken care of
dependent personality
636
complication of antipsychotic treatment and can occur at any time. cogwheel if tremor otherwise leadpipe rigidity, dystonia, akinesia, fever, deiphoresisi, tachy, HTN, rhabdo
neuroleptic malignant syndrome, stop offending agen and give dantrolene or bromocriptine
637
starts shortly after medication is given, delirium, agitation, tachycardia, diaphoresis, diarrhea, myoclonus, hyperreflexia, hyperthermia, seizures, rhabdomyolysis, renal failure
serotonin syndrome, serotonin antagonist or cyproheptadine
638
major difference between serotonin syndrome and NMS is that
serotonin syndrome has myoclonus with hyperreflexia
639
decreased FEV/FEV1 ratio | preserved ratio
obstructive | restrictive
640
what does dclo stand for | what process is characterized by this due to alveoloi being destroyed and unavailable for gas exchanged
diffusion capacity of lungs COPD
641
treatment course for chronic asthma
albuterol then inhailed corticosteroid, then salmeterol
642
chronic cough with sputum production due to destruction of lung parenchyma
COPD | stable - LABA (ipratropium) then oxygen
643
chronic productiv ecought for 3 or more months in each of 2 consecutive years
chronic bronchitis
644
young COPD patient with emphysematous changes that have an apical pedominance
alpha 1 antitrypsin deficiency
645
clinical cyanosis with normal PaO2
methemoglobinemia, methylene blue
646
hypoxia workup after hypoxia is found then do what? if normal ? if increased its what two things and what do you do for it
A-a gradient give O2 - high altitude or low Fio2 shunt - increase pressure with ventilation (lobar pneumonia, ards) v/q mismatch - give oxygen
647
pleural effusion | calculate what?
lights criteria low is transudative 0.5/0.6/66% protein ratio /ldh ratio/ldh pleural high is exudative
648
tracheal deviation away from side of injury
tension pneumothorax
649
associated with higher mortality in pulmonary embolism
elevated troponin
650
noncaseating granulomas in various organs, fever, cough, weight loss, arthritis grueling features granulomas, RA, uveities, erythema nodosum, lymphadenitis, intersitial fibrosis, negative PPD, gammaglobulinemia, parotid gland swelling
sarcoidosis, corticosteroids or methotrexate
651
neurocognitive impairment, morning hedache, poor sleep or impotence, obese, HTN ``` STOP BANG snorring tired apnea HTN BMI AGE neck gener is male ```
sleep apnea, bipap
652
cheyne stokes breathing - deep rapid breathing followed by decreased ventilation and apnea is often cause by stroke or HF
central sleep apnea
653
recurrent pulmonary infectiosn, sinusitis, meconium ileus, intussusception, DM, malabsorption, infertility, nasal polyps, clubbing of nails
cystic fibrosis
654
severe headache, throbbing left temporal pain, flashes of light in right visual field, weakness and numbness on the right side of her body, nausea and vomiting
migraine , IV hydration, promethazine, metoclopramide, caffeine, sumatripatain or ergotamine
655
bilateral band-like throbbing pain, pain and stiffiness in neck and shoulder
tension headache
656
intermittent headache in right temporal lobe with blurred viison in right eye and pain in jaw during mastication
temporal arteritis, steroids
657
high fever, severe headache, photophobia, lives in college dorms
meningitis, ceftriazone, vanc, dexamethasone
658
severe headache, nausea, vomiting, stopped talking metoprolol hx of HTN
hypertensive emergency, restart meds
659
forgetfulness (phone numbers, way home), difficulty performing daily activitys, gradually progressed
alzheimer disease, donepezile, rivastigmine, or memantine
660
difficulty walking, memory loss, urinary incontinece,
Normal pressure hydrocephalus, shunt
661
seizure after being admitted 2 days ago for emergency trauma surgery, anxious, agitated, irritable, tachycardic, nausea, diarrhea, sweating, and insomnia, tremors, hallucinations
alcohol withdrawal
662
drowsy, stiffened, fell backward, lost consciousness, no respiration for 1 minute, jerking motion of all four limbs
tonic clonic seizure
663
syncope, fatigue, dizziness for 5 days, loss of consciousness, prodrome of lightheadedness, medications include propranolol, digxin, and diltiazem
complete heart block
664
2 yo childsudden onset of shortness of breath and cough, had URI 4 days ago. earlier today was playing with peanuts
forgien body ingestion
665
HIV postivie patietn with shortness of breath, malaise, droy cough, fatiuge, and fever
PCP, bacrim
666
generalized weakness, left flank discomfort, nausea, constipation with 20 lb weight loss over 4 months
renal cell carcinoma
667
alcoholic with epigastric pain that radiated to his back, nausea, vomiting, anorexia, no PUD
acute pancreatitis
668
newborrn bilious vomiting, irritability, poor feeding, lethargy, acute episode of rectal bleeding
malrotation with volvulous
669
new born baby, mom had DM presents with tachypnea, hypoxia, failure to thrive, nasal flairing and retractions. heart murmur present breath sounds are clear
HOCM, should resolve on its own