Stephan Guyenet: The Hungry Brain Flashcards
What causes overeating and obesity? (Also the Theme of “The Hungry Brain”)
A mismatch between ancient survival circuits in the brain and an environment that sends these circuits the wrong messages. (p5)
What proportion of deaths among older US adults are linked to excess weight?
Up to one-third. (p11)
What is the energy balance equation?
Change body energy = energy in - energy out (p12)
What is the primary reason that some foods are more fattening than others?
They coax us to eat more calories. (p13)
How many more calories per day did people eat in 2005 versus 1975?
218 calories / day. (p14)
How many fewer calories per day must you eat for every pound you want to lose?
10 calories / day. (p16)
What’s the most effective way to get a normal rat or mouse to overeat? What’s the name of the diet?
Feed them palatable human foods: the cafeteria diet. (p19)
What is “opportunistic voracity?”
When a variety of free, tasty foods are available, people will overeat. (Researcher: Eric Ravussin) (p21)
Why do scientists compare lamprey brains with human brains?
Because they are our most distant vertebrate relatives; their ancestors diverged from our own some 560 million years ago. (Researcher: Sten Grillner) (p23)
What decision-making apparatus is in both lamprey and human brains?
The basal ganglia (p26)
What three things must an effective selector have?
- Choose one option
- Choose the BEST option
- Select decisively among options
(p25)
What is the portion of the basal ganglia that receives most incoming signals from other parts of the brain?
The striatum. (p26)
Ultimately, what does the basal ganglia choose?
Which behavior gets access to the muscles and turns away the rest (p26)
What does the striatum do?
The striatum receives “bids” from other brain regions, each of which represents a specific action, and selecting the strongest bid (p26-27)
How much of our body weight does the brain represent, and how much energy does it use?
2% of bodyweight, up to one-fifth of energy (p29)