Sterile and non sterile compounding 7 Flashcards Preview

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Flashcards in Sterile and non sterile compounding 7 Deck (35):
1

Can non-Commercially formulations still be compounded?

yes

2

what should sterile preparations meet?

identity, potency, quality and purity

3

where should sterile preparations be made?

in a designated area

4

can sterile and nonsterile substances be compounded in the same area?

no

5

What is known as the control or the buffer area?

This is where the Laminar flow bench is located, this areas is kept separate from non-sterile compounding.

6

What is the anteroom used for?

used to decontaminate supplies and equipment

7

What are the compounding sterile preparations categories?

Low, Medium and High Risk

8

Which risk involves no more than three commercially available products, and two entries in the sterile compounding bag?

Low risk

9

Which Risk involves, compounding using aseptic manipulations in an ISO class 5 environment?

Low Risk

10

Which Risk involves, pooling multiple vials or containers to prepare a CSP for one or more patients

Medium Risk

11

Which Risk involves a long compounding process

Medium Risk

12

A high risk, contains ; using a non-sterile formulation to prepare CSP, T or F?

True

13

Which risk, poses a major threat when it involves mixing sterile ingredients in non-sterile devices?

High Risk

14

Can compatibility issues arise between a drug and an IV?

yes

15

What are some factors of incompatibility?

visible or chemical changes

16

What does the EPA set?

they set laws, on where you should and can dispose of pharmaceutical waste

17

What are the categories of hazardous waste?

P U K F

18

What are some characteristics of hazardous waste?

toxicity, corrosivity, ignitability and reactivity

19

What is labeled as commercial chemical products?

P and U, this includes drugs like chemotherapeutics agents, warfarin and nicotine

20

hazardous waste should have a seperate controls and have ?

negative pressure room to house engineering controls

21

What are some antimicrobial preservations?

IV solutions and ophthalmics

22

What is the meaning of antimicrobial preservations?

used for bacteriostatic preparations to prevent bacteria from growing

23

What is the meaning of Antioxidants?

prevent oxidation of the component drug

24

What are chelating agents?

they reduce the toxic effect on metals

25

emulsifiers?

used to create a uniformed concentrations of an active drug in a solution

26

pH buffers?

help stabilize a solution against degradation

27

solute?

a substance dissolved in a solvent

28

tonicity agent?

help adjust formulations to an appropriate isotonic range

29

vehicle

serves as solvent

30

What are some single use containers and what does that mean?

they do not contain microbial preservatives, they can be viles and or ampules

31

viles should not be used no more than ____ hours after the initial needle puncture

6

32

open ampules should be stored, True or False?

false; they should not be stored

33

Multiple use containers have what?

antimicrobial preservatives, this allows for withdrawal of contents over a period of time

34

what is the BUD on the multiple use container?

28 days

35

What is the most common glass container that is used in a sterile preparation?

borosilicate