STI Flashcards
(31 cards)
Complications of urethritis
acute prostatitis and epididymitis for men
salpingitis, endometritis and abscess for women
life cycle of chlamydia
- elementary body attaches to specific host cell receptor
- EB endocytosed and resides in host membrane bound phagosome
- EB becomes large reticulate body
- multiplication of reticulate bodies by binary fission within the host cell and phagosome becomes inclusion
- condensation into EB forms
- lysis and host cell death
lab diagnosis of chlamydia
- examining first void urine
- gram stain (swab up the urethra)
- tests include
- enzyme immunoassays
- cultures
what organisms cause cervicitis
C. trachomatis
N. gonorrhoeae
ureaplasma
mycoplasma
clinical presentation of cervicitis
vaginal discharge bleeding itching irritation dyspareunia
lab diagnosis of cervicitis
history and examination lab diagnosis - microscopy -evaluate for vaginal vaginosis -rapid antigen tests -culture -pcr -fluorescent antibody tests
vulvovaginitis clinical presentation
vaginal discharge
vulvar itching
irritation
odor
diseases of vulvovaginitis
bacterial vaginosis
trichomoniasis
candidiasis
bacterial vaginosis organisms
gardnerella vaginalis mycoplasma hominis ureaplasma spp anaerobes - prevotella - porphyromonas - peptostreptococcus - mobiluncus
risk factors of bacterial vaginosis
sexual activity at an early age
having numerous sex partners
frequent douching
lab diagnosis of bacterial vaginosis
thin consistency discharge
vaginal squamous epithelial cells typically coated with gram variable G. vaginalis
polymorphonuclear leukocytes can also be demonstrated on the normal vaginal wet mount preparation
pH test paper > 4.5
amine or whiff test to determine if pH is higher than 4.5
culture
DNA hybridization for G vaginalis
treatment for bacterial vaginosis
oral treatment metronidazole
clindamycin intravaginally
complications include :
preterm labour
low birth weight
miscarriage
symptoms of trichomonas vaginalis
itching burning dysuria lower abdominal pain genital redness smelly vaginal discharge elevated pH
laboratory diagnosis of trichomonas
microscopy in wet saline culture (diamond medium) in house PCR POC rapid antigen test oligonucleotide probe test in the office
treatment for trichomonas
Metronidazole
tinidazole
treat sexual partner and all asymptomatic patients
candidiasis causes
c, albicans
c. parapsilosis
c. glabrata
(yeast infections)
symptoms of candidiasis
dysuria
white discharge
treatment of candidiasis
Azole antifungal drugs
causes of genital ulcer disease
herpes, syphilis, chancroid
symptoms of gentital herpes
painful vesicles fever myalgias malaise dysuria inguinal lymphadenopathy lesions develop into ulcers containing HSV particles
Lab diagnosis of genital herpes
fluid from vesicles
cervical swabs
PCR
treatment of genital herpes
no cure acyclovir valacyclovir famciclovir suppressive therapy may reduce recurrence
diagnosis of syphilis
treponemal tests
non treponemal tests
Serum antibody tests
Spirochetes
treatment of syphilis (primary and secondary)
benzathine
doxycycline
ceftriaxone
azithromycin
