STIs

Question 1

What is the pathogen causing gonorrhoea?

Answer 1

Neiserria gonorrhoeae

Question 2

What are the symptoms of gonorrhoea in men?

Answer 2

• asymptomatic 10
• thick profuse yellow discharge
• dysuria
• rectal, pharyngeal infection

Question 3

What are the symptoms of gonorrhoea in women?

Answer 3

• aymptomatic > 50%
• vaginal discharge
• dysuria
• post-coital/intermenstrual bleeding

Question 4

What are the complications of gonorrhoea in males?

Answer 4

• epididymitis
• acute monoarthritis
• gonococcal infection

Question 5

What are the complications of gonorrhoea in women?

Answer 5

• PID
• Bartholin’s abscess
• acute monoarthritis
• gonococcal infection

Question 6

What are the investigations for gonorrhoea?

Answer 6

• nucleic acid amplification test (NAAT)
• urine/swab vagina/rectum/throat
• gram stain smear
• urethra/cervix.rectum
• swab culture

Question 7

What is the treatment for gonorrhoea?

Answer 7

• ceftriaxone
• 1g, im
• test at 2 weeks + 3 months

Question 8

What is the pathogen causing chlamydia?

Answer 8

• chlamydia trachomatis serovars D-K

Question 9

What are the symptoms of chlamydia in men?

Answer 9

• asymptomatic > 70%
• slight watery discharge
• dysuria
• conjunctivitis

Question 10

What are the symptoms of chlamydia in women?

Answer 10

• asymptomatic > 80%
• vaginal disharge
• dysuria
• intermenstrual/post-coital bleeding
• conjunctivitis

Question 11

What are the complications of chlamydia in men?

Answer 11

• epididymitis
• reactive arthritis
• Reiter’s syndrome

Question 12

What are the complications of chlamydia in women?

Answer 12

• PID -> ectopic pregnancy
• pelvic pain
• infertility
• reactive arthritis
• Reiter’s syndrome

Question 13

What are the investigations for chlamydia?

Answer 13

• NAAT
• first void urine (men)
• swab cervix/urethra/rectum

Question 14

What is the treatment for chlamydia?

Answer 14

• doxycycline
• 100mg bd 1 week
• azithromycin (if pregnant)
• 1g po once
• test 3-12 months

Question 15

What is the pathogen causing herpes?

Answer 15

• herpes cimplex virus 1 + 2

Question 16

What are the symptoms of herpes?

Answer 16

• aymptomatic 80%
• curning/itching ->blistering -> tender ulceration
• tender inguinal lymphadenopathy
• flu-like symptoms
• dysuria
• neuralgic pain in back, legs, pelvis

Question 17

What are the complications of herpes?

Answer 17

• autonomic neuropathy (urinary retention)
• neonatal infection
• secondary infection

Question 18

What are the investigations for herpes?

Answer 18

• clincal diagnosis
• PCR swab from lesion

Question 19

What is the treatment for herpes?

Answer 19

Primary outbreak:

• aciclover
• lidocaine ointment

Infrequent recurrences:

• lidocaine ointment
• aciclover

Frequent recurrences:

• aciclover long term

Question 20

What is the pathogen causing trichomoniasis?

Answer 20

• trichomonas vaginalis

Question 21

What are the symptoms of trichomoniasis?

Answer 21

• usually asymptomatic
• profuse, thin vaginal discharge

Question 22

What are the complications of trichomoniasis?

Answer 22

• miscarriage
• preterm labour

Question 23

What are the investigations for trichomoniasis?

Answer 23

• PCR vaginal swab
• microscopy of wet preparation of vaginal discharge

Question 24

What is the treatment for trichomoniasis?

Answer 24

• metronidazole

Question 25

What is the pathogen causing anogenital warts?

Answer 25

* HPV 6 + 11

Question 26

What are the symptoms of anogenital warts?

Answer 26

* lumps- cauliflower texture * itching * bleeding

Question 27

What are the complications of anogenital warts?

Answer 27

* neonatal laryngeal papillomatosis

Question 28

What are the investigations for anogenital warts?

Answer 28

* clinical diagnosis * biopsy if unusual

Question 29

What is the treatment for anogenital warts?

Answer 29

* podophyllotoxin * imiquimod * cryotherapy * diathermy * scissor removal

Question 30

What is the pathogen causing syphilis?

Answer 30

* treponema pallidum

Question 31

What are the symptoms + stages of syphilis?

Answer 31

* primary- local ulcer (chancre) * secondary- rash, mucosal ulceration, neuro, alopecia * early latent- asymptomatic (≤ 2 yrs) * late latent- asymptomatic (≥ 2 yrs) * tertiary- neuro, CVS, gummatous

Question 32

What are the complications of syphilis?

Answer 32

* neurosyphilis - cranial nerve palsies - cardiac/aortic * congenital syphilis

Question 33

What are the investigations for syphilis?

Answer 33

* clinical diagnosis * serology - TP, IgGEIA, TPPA, RPR * PCR on sample from ulcer

Question 34

What is the treatment for syphilis?

Answer 34

≤ 2 yrs, no neuro: * benzathine penicillin * doxycycline ≥ 2 yrs, no neuro: * benzathine penicillin * doxycycline