Stomach Flashcards
(17 cards)
Rugae
Located on mucosal layer
Large, longitudinal folds
Allow the stomach to expand when needed
Main function
Food storage and digestion
Chyme
Chemical breakdown of food
Bolus –> becomes chyme in the stomach
Cardia
Small
1st top/part
Surrounds cardial orifice (through which food enters the stomach from the esophagus)
Fundus
Stomach’s dome-shaped part
Beneath diaphragm and bulges above the cardia
Body
Mid-portion
Continuous with pyloric part
Pyloric region
Terminal part that meets duodenum
Pyloric sphincter: separates stomach from small intestine; controls stomach emptying
Mucous neck cells
Secrete mucus
Parietal cells
Secrete HCl and IF
HCl: needed for activation of pepsin
IF: intrinsic factor; needed to absorb B-12 vitamin in the small intestine
Chief cells
Secrete pepsinogen (inactive pro-enzyme of pepsin) Secrete lipases
Pepsin
1 digestive protein enzyme in the stomach
Enteroendocrine cells
Secrete chemical messengers directly into interstitial fluid of lamina propria D cells G cells Enterochromaffin cell Enterochromaffin-like cells
D cells
Secrete somatostatin (inhibitor)
G cells
Secrete gastrin (stimulatory; excites parietal cells)
Enterochromaffin cells
Secrete serotonin (excites smooth muscles to contract)
Enterochromaffin-like cells
Secrete histmine #1 stimulator of HCl
PD-1 cells
Secretes ghrelin
Hormone that controls hunger
Starved or in-between meals –> increased gherlin