Streptococcus pneumoniae

Question 1

Streptococcus pneumoniae

Answer 1

α-hemolytic, Gram+ diplococci

Question 2

Streptococcus pneumoniae

Which type are virulent

Answer 2

Only encapsulated strains
(􀀂smooth􀀃 colonies) are
virulent

Question 3

Pneumococcal pneumonia
EPI:
Trt:

Answer 3

High carrier rates for s. pneumoniae
Vaccine Available.
Usually Penicillin

Question 4

Klebsiella pneumonia

EPI:
TRT

Answer 4

Resistant to AB
Fatal nosocomial
No Vaccine!

Question 5

Mycoplasmal pneumonia

TRT

Answer 5

No Vaccine

Question 6

S.pneumoniae virulence factors

Answer 6

α-hemolysis (erythocyte lysis by pneumolysin (cholesterol-dependent action),
hemoglobin destruction)
(pneumolysin also suppresses oxidative burst in phagocytes)

capsule (>90 serotypes) is antiphagocytic and its anti-complement features facilitate
bacteremia (presence in blood circulation) and thus
spreading to other tissues like brain (meningitis)*, peritonitis, arthritis, endocarditis
Some 40% of bacterial otitis may be caused by S.pneumococcus

secretory IgA protease