Streptococcus Pneumoniae Flashcards
(7 cards)
0
Q
Character (5)
A
Catalase - Optochin S Alpha hemolytic NOT normal flora Carriage in throat (~10%)
1
Q
Culture
A
Draughtsman colonies in blood agar
2
Q
Virulence Factors (2)
A
Capsule (anti-phagocytic, different strains produce diff type)
Pneumolysin (memb-damaging)
3
Q
Clinical Presentation (6)
A
Endocarditis Pneumonia URTI (sinusitis, otitis media) Meningitis Peritonitis (spontaneous) Septicemia (=SIRS, may seed to joints, pericardium)
4
Q
Predisposing Conditions (4)
A
Age (young, old)
Chronic lung/liver/heart/renal disease
Immunosuppression
Hyposplenism (encapsulated organism clearance)
5
Q
Diagnosis (2 Conditions)
A
Pneumonia: culture sputum + blood, urine Ag
Meningitis: culture CSF + blood, urine Ag
6
Q
Treatment (2 Conditions + 1 Note + Prevention)
A
Pneumonia + RTI: pen G/amox
Meningitis: ceftri + vanco
Note: resistance increasing, check with ID physician
Old vaccine: polysaccharide capsule from 23 strains
New vaccine: conjugate of capsule matl + protein carrier
