Streptococcus Pneumoniae Flashcards
1
Q
Virulence Factors
A
Capsule for evasion
Pili
Choline Binding Protein A- involved in adhesion
Toxins- Pneumolysin for pro-inflammatory response
2
Q
Infections
A
Non-Invasive- Pneumonia, otitis media, sinusitis
Invasive- BSI, Meningitis
3
Q
Isolate on what agar
A
Blood agar at 37C
4
Q
Confirmatory tests
A
Optochin sensitive
Bile solubility
Commercial tests for the capsule
5
Q
What is the bile solubility test?
A
A test to see if the organism can use bile for during cell division. They use enzymes to lyse the cell walls during cell division. The bile salts activate them. Positive results would be where there is lysis on the plate
6
Q
What kind of organism is S.Pneumonia
A
Alpha haemolytic, gram positive cocci, catalase negative
