Stroke Flashcards

(34 cards)

1
Q

What is the definition of a stroke?

A

Is sudden onset of focal or global neurological symptoms caused by ischaemia or haemorrhage and lasts more than 24hrs

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2
Q

What is a TIA?

A

Transient ischaemic attack
Is if symptoms resolve within 24hrs

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3
Q

What are the main causes of an ischaemic stroke?

A

Carotid plaque with arteriogenic emboli
Cardiogenic emboli - AF, valve disease and left ventricle thrombosis
Small artery disease
Carotid dissection

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4
Q

What are the risk factors of a stroke?

A

Previous stroke, age, male and FH
Smoking, Oestrogen pills, obesity, diabetes, alcohol, cocaine, high BP and cholesterol

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5
Q

What is the most important modifiable risk factor?

A

Hypertension
Esp. lacunar ischaemic strokes and small vessel haemorrhages esp. in brainstem, basal ganglia and subcortical areas

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6
Q

Describe AF and strokes

A

5 x increased risk of emboli with atrial fibrillation
More severe strokes
Anticoagulants reduce risk of ischaemic stroke

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7
Q

What is the anterior circulation of the brain?

A

2 x internal carotid arteries - 2 x anterior cerebral arteries and 2 x middle cerebral arteries

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8
Q

What is the posterior circulation of the brain?

A

2 vertebral arteries - 1 basilar artery
3 pairs of cerebellar arteries
2 posterior cerebellar arteries

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9
Q

Where are Borderzone anastomoses?

A

Between peripheral branches of anterior, middle and posterior cerebral arteries

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10
Q

Where does the carotid system supply?

A

Most of hemispheres and cortical deep white matter

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11
Q

Where does vertebro-basilar system supply?

A

Brainstem, cerebellum and occipital lobes

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12
Q

What are the functions of the frontal lobe?

A

High level cognitive functions
Memory
Motor control of speech
Motor cortex
Urinary continence
Emotion and personality

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13
Q

What are the functions of the parietal lobe?

A

Sensory cortex, sensation, awareness of parts of body, spatial orientation and ability to perform learned motor tasks

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14
Q

What are the functions of the temporal lobe?

A

Primary auditory area, comprehension of speech, visual, auditory and olfactory perception, learning and memory

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15
Q

What does an ACA and MCA more cause?

A

ACA - more leg than arm weakness
MCA - face and arm more than leg weakness

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16
Q

What is the function of the occipital lobe?

A

Primary visual cortex, visual perception and involuntary smooth eye movement

17
Q

What are the clinical presentations of a stroke?

A

Sudden onset loss of function - motor, sensory, dysphasia, neglect, vision affected and gaze palsy
Ataxia, vertigo, and nystagmus

18
Q

What classifies strokes?

A

Oxford Community Stroke Project Classification OCSP

19
Q

What are the subtypes of strokes?

A

TACS - total anterior circulation stroke
PACS - partial anterior circulation stroke
LACS - lacunar stroke
POCS - posterior circulation stroke

20
Q

Describe a total anterior circulation stroke (TACS)

A

Main artery to one hemisphere
Has 3 symptoms - complete hemiparesis/ numbness, loss of vision on one side and loss of awareness on non-dominant side or dysphasia dominant
Blocked carotid or middle artery

21
Q

Describe a partial anterior circulation stroke

A

Branch of main artery
In between TACS and LACS
Has 2/3 of TACS criteria or one higher cortical defect (inattention or dysphasia) or monoparesis

22
Q

Describe a lacunar stroke

A

Small perforating artery
Movement and sensation pathways
Weakness and numbness of face, arm and leg
May have dysarthria
Ataxic hemiparesis
No effect on higher function

23
Q

Describe posterior circulation stroke (POCS)

A

Any posterior artery
Combination of symptoms - loss of balance, vertigo, double vision, dysarthria and visual loss

24
Q

Describe a basilar artery occlusion

A

Ischaemia in pons, predominantly motor signs, bilateral but asymmetrical
Alteration of consciousness common
May present with reduced consciousness

25
What are some things which can mimic a stroke?
Seizures, syncope, sugar, sepsis, severe migraine, space occupying lesions, vestibular disorders, demyelination and mononeuropathy
26
What type of symptoms are more present in strokes?
Negative Loss or reduction in CNS function Loss of vision, sensation and limb power
27
Describe a migraine aura
Is due to cortical spreading depression Classical spreading onset and causes visual disturbances Can be sensory, motor and speech disturbance too
28
What is Hoover's sign?
Test hip extension - weak Test contralateral hip flexion against resistance - hip extension has become strong
29
What are the investigations used for a stoke?
Routine blood tests, CT/MRI, ECG and Holter, and carotid doppler US Some patients may need Echo, cerebral angiogram and hyper-coagulable blood screen
30
What acute stroke treatment has biggest effect on individual?
Thrombolysis and thrombectomy Thrombolysis by TPA
31
What stroke treatment has the biggest effect on most patients?
Stroke unit admission
32
What is the criteria for TPA use?
Use under 4.5hrs from symptom onset Disabling neurological deficit Symptoms more than 60 mins Consent is obtained
33
What is the exclusion criteria for IV TPA?
Anything which increases risk of haemorrhage - blood on CT, recent surgery, recent episode of bleeding and coagulation problems BP more than 185 systolic and 110 diastolic Glucose more than 2.8 or less than 22mmol/l
34
What is used for secondary prevention of stroke?
Anti-hypertensives, anti-platelets, lipid lowering agents, warfarin for AF and carotid endarterectomy in ICA stenosis