stroke Flashcards

(58 cards)

1
Q

Bamford classification of stroke

A

TACS

PACS

Lacunar (pure sensory or motor, affects face arms and legs usually)

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2
Q

TACS vs PACS

A

TACS = 3/3:
Homonymous hemianopia
Hemiplegia
HIgher cortical dysfunction e.g. dysphasia, sensory or visual neglect

PACS = 2/3

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3
Q

What additional thing to test if left sided weakness i.e. right sided lesion

A

Test for neglect

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4
Q

What additional thing to test if right sided weakness ie left sided lesion

A

Speech/language

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5
Q

Broca’s and wernicke’s relevance

A

Broca’s (Frontal lobe) = expressive dysphasia

Wernicke’s (temporal lobe) = receptive dysphasia

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6
Q

stroke and TIA definition

A

rapid onset focal neurological deficit due to vascular lesion lasting > 24h for stroke and < 24h for TIA

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7
Q

Which body part more affected in ACA and MCA stroke

A

ACA: Legs > arms/face
MCA: Face + arms > legs

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8
Q

POCS features

A

cerebellar features usually/ pure visual loss/ brain stem

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9
Q

stroke features on inspection

A

Walking aids
NG tube/ PEG tube
Fixed deformities (flexed upper and extended lower)
Splints (Wrist or ankle)

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10
Q

Features on inspecgion/examination of cranial nerves

A

UMN sign - often facial weakness, homonymous hemianopia

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11
Q

On inspection of speech

A

dysarthria (spastic) or dysphasia (Expressive or receptive)

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12
Q

On examination of limbs

A

ANy UMN signs and reduced sensation

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13
Q

What would you offer to examine at the end of your examination?

A

Bedside swallow assessment

Fundoscopy (hypertensive and diabetic retinopathy)

HIgher cortical functions e.g. sensory or visual inattention

Cognition (MOCA)

CVS exam - pulse (AF), carotids for bruits, BP, murmurs

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14
Q

Stroke investigations acutely

A

Bedside:
Urine dip (glucose, protein, blood)
CBG
ECG: AF

Bloods: routine and cardiac risk factors, vasculitis screen if young stroke

CT Head

CTA if eligible for thrombectomy

Carotid dopplers

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15
Q

What would you do in the case of an acute stroke

A

“I would ensure this patient is medically stable and perform an A-E assessment. I would ascertain the history to see if they are within the window for thrombolysis (4.5 hours) or thrombectomy (24h).

I would then calculate their NIHSS score and arrange an urgent CT head and CT angiogram. I would also contact the thrombolysis/HASU.”

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16
Q

Useful statement when presenting examination findings in suspected stroke

A

“Asymmetrical pattern of pyramidal weakness”

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17
Q

WHy would you do a cranial nerves exam in a patient with stroke?

A

Looking for homonymous hemianopia

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18
Q

Stroke investigations (Chronic)

A

24h/7-day holter
lipids, statins, BP
Carotid dopplers (would not need this if already had a CTA)

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19
Q

Extra investigations in young stroke (< 55)

A

Clotting screen, vasculitic screen
MRA if ? dissection
Bubble echo

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20
Q

Acute management of stroke

A

A-E

Check if eligible for thrombolysis/thrombectomy

NIHSS

CTH/CTA

Liaise with thrombolysis team/HASU

Thrombolysis

Following above
Aspirin 300mg for 2 weeks followed by clopi/anticoag if AF
Referral to specialist multidisciplinary stroke unit
DVT prophylaxis

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21
Q

Chronic stroke management

A

Possible referral for carotid endarterectomy if anterior circulation stroke and stenosis > 70%

MDT (neuro stroke specialist, neruo physio, OT, dietitian, SALT, GP, psychologist)

Management of CVS Risk factors (BP, diabetes, hyperlipidaemia)

Swallow assessment +/- NG/PEG feeding

OT/PT

Dietitian

SALT

No driving for 4 weeks

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22
Q

What DVT prophylaxis should be used in storke patients?

A

IPC

NOT LMWH OR TEDS

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23
Q

Hemorrhagic stroke management

A

if < 6 hours, manage bP with systolic target 140-150

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24
Q

Complications of stroke

A

Malignant MCA syndrome
Haemorrhagic transformation
Re-infarction
Hydrocephalus (in haemorrhagic)
Seizures

Stroke specific:
- Aspiration
- Incontinence
- Hypertonia and pain
- PE/DVT

25
Stroke risk scores in patient's with TIAs
ABCD2
26
stroke DDx
Ischaemic - Thrombotic - Embolic - Carotid artery stenosis Haemorrhagic - Hypertension - AVMs - EDH/SDH SOL Demyelinating lesion (less common)
27
What is sent in the vasculitic and thrombophilia screen?
ESR ANA ANCA Anti ds-DNA Lupus anticoagulant Anti-phospholipid Anti-b2-glycoprotein Factor V Leiden Protein C and S Anti thrombin III
28
what drug is used for thrombolysis?
Alteplast
29
Lateral medullar syndrome - location of infarct
PICA
30
Another name for lateral medullary syndrome
Wallenberg syndrome
31
Symptoms of wallenberg
ipsilateral: homonymous hemianopia/ cerebellar signs / acute vertigo/horner's/ loss of facial pain and sensation contralateral: loss of limb pain and temperature sensation
32
pain and temp sensation in wallenber's
ipsilateral loss in face contralateral in limbs
33
what medication would you give if the patient is arleady on aspirin and has a stroke?
clopidogrel
34
what is the best imaging modality to pick up an ischaemic stroke?
MRI
35
Causes of cerebellar syndrome (PASTRIES)
Paraneoplastic Alcohol (wernicke's acutely, cerebellar degenration chronic) Sclerosis - MS Tumour (posterior fossa SOL) Rare/recessive FA, at, Dominant SCA Iatrogenic - phenytoin, lead Endocrine - hypothyroidism Stroke
36
Cerebellar features, INO, young female
ms
37
optic atrophy + cerebellar
Friedrich's + MS
38
Clubbing, radiotherapy tattoo + cerebellar
Bronchial carcinoma + paraneoplastic
39
stigmata of CLD, unkempt + cerebellar
EtOH
40
Peripheral neuropathy + cerebellar
Friedrich's, alcohol
41
Gingival hypertrophy and cerebellar
Phenytoin
42
What features do lesions of the cerebellar vermis cause?
truncal ataxia (impaired sitting and walking and balance) but no limb ataxia
43
what direction is the fast phase of nystagmus in peripheral/vestibular lesions?
Fast phase is AWAY FROM THE LESION AND THE DIRECTION DOES NOT CHANGE (in cerebellar the fast phase changes on gaze alteration)
44
what does pseudoathetosis suggest
sensory ataxia
45
how many von hippel lindau cause cerebellar syndrome?
cerebellar haemangioblastomas
46
which cause is most commonly associated with cerebellar vermis lesions?
chronic alcohol abuse -> degeneration of vermis
47
miller-fisher triad
ophthalmoplegia ataxia hyporeflexia
48
which cranial nerves involved in the cerebellopontine angle?
5,6, 7,8
49
cerebellar syndrome + parkinsonism
multisystems atrophy type C
50
cerebellar features, young male, wheel chair, pes cavus, freestyle libra in situ
friedrich's ataxia
51
cerebellar features and ipsilateral horner's + ipsilateral loss of facial sensation
lateral medullary syndrome
52
Common causes of bilateral cerebellar syndrome
Genetic - SCA - Friedrich's - Ataxia telangiectasia Metabolic - Hypothyroidism Drug induced - phenytoin, lead - chronic EtoH MSA-C Neoplastic - Paraneoplastic - von hippel lindau -> cerebellar haemangioblastomas - NF2 Rare: Demyelination B/L stroke B/L tumours
53
Common causes of unilateral cerebellar syndrome
Demyelination SOL Stroke - Within cerebellar hemisphere - Within brainstem causing lateral medullary syndrome
54
Ix in a patient with cerebellar features
If acute (Follow stroke protocol) MRI brain ANti-neuronal antibodies Genetic testing if FH Stroke specific work up Age appropriate malignancy screen
55
causes of spastic paraperesis and cerebellar signs
Demyelination SCA Friedrich's Syringomyeliaw
56
what would you do to complete your exam of a cerebellar pt
do full uL/LL exam Perform FUNDOSCOPY! (OPTIC ATROPHY in MS, friedrich's)
57
what inherited genetic condition are cerebellopontine angle tumours commonly associated with?
nF 2
58