Stroke, Headache, and HTN Flashcards
(35 cards)
Stroke symptoms
Symptoms vary: location, severity, type dependent
- Weakness/numbness face/limbs, one side
- Confusion, difficulty speaking/understanding
- Agitation, seizure
- Vision changes – one/both eyes, visual field cut
- Difficulty walking, ataxia, loss of coordination
- Dizziness, vertigo, loss of balance
- Atraumatic loss of consciousness
- Sudden, severe headache
- Visual changes can be stroke!!! If someone cant see out of one eye, this may be a stroke
- Hemorrhageic are the ones associated with HA! Ischemic strokes are not
Risk Factors for stroke
- TIA or previous CVA – your risk of stroke is phenomenally higher!
- HTN
- DM
- Atrial Fibrillation
- EtOH, IVDU, stimulants
- Atherosclerosis
- High cholesterol
- Sickle Cell
- Obesity/inactivity
- Tobacco
- Increasing age
- Young people too!!
- Heredity
- Family Hx of CVA
- Ethnicity
- African Americans
- Hispanic Americans
- Gender
- Men > Women
- Women > for SAH
Critical hx for stroke
- When did symptoms begin?
- Treatment is time dependent
- When were you/they last normal?
- Sudden or gradual onset?
- What are the symptoms, exactly?
- Symptoms persistent or transient?
- On anticoagulation??
- PMHx, prior function, meds, risk factors
- Trauma? Syncope? N/V?
- Headache??
- Ask contraindications for tPA, thrombolytics
Ischemic CVA
- ~85% of all strokes
- Thrombotic
- Atherosclerosis, gradual vessel occlusion
- Sx onset may be gradual, stuttering
- May have hx TIA
- Embolic
- Sudden occlusion; sudden, fixed deficit
- A fib, cardiac thrombus, endocarditis
- Early on – no headache
Hemorrhagic CVA
- ~15% of all strokes
- Intracerebral Hemorrhage
- Subarachnoid Hemorrhage
- Causes – vessel ruptures due to:
- HTN
- Cocaine, Meth, stimulants
- Aneurysm bursts open
- Arteriovenous Malformation (AVM)
- Trauma while on anticoagulation
- Headache, ALOC are cardinal sx’s
Brain review
-Left is dominant hemisphere:
All right-handed
80% left-handed
-Right is dominant in 20% lefties
Stroke syndromes
Anterior circulation CVA
- Carotid artery origin
- Anterior Cerebral Artery
- Middle Cerebral Artery
Posterior circulation CVA
- Vertebral artery origin
- Posterior Cerebral Artery
- Vertebrobasilar stroke
- Cerebellar stroke
Lacunar strokes
Anterior circulation CVA - anterior cerebral artery
- Motor: Contralateral weakness
- Leg, foot > arm
- Sensory: Contralateral deficit
- Leg sx’s > arm sx’s
- Loss of frontal lobe control
- Personality change
- Perseveration – repeat yourself over and over again
- Incontinence
- Gait disturbances
- Apraxia – can’t perform tasks or follow commands even though they know the task and wish to follow the command. Several specific types – you cannot execute something you understand
anterior circulation CVA - middle cerebral artery
- Most common – bad if big/central
- Motor: Contralateral weakness
- Face/arms > legs
- Facial droop
- Sensory: Contralateral deficit
- Arms > legs
- Dominant hemisphere: aphasia
- Non-dominant: neglect
- Eyes turned toward side of stroke
- Homonymous hemianopsia – look at next slide for example
Posterior circulation CVA - Posterior cerebral artery
- Occipital cortex affected
- Vision loss, cortical blindness
- Normal eye, eye reflexes
- May go un-noticed by patient
- Homonymous hemianopsia
- Ipsilateral CN 3 palsy
- Minimal motor findings
- Contralateral
- Cortical blindness – when the person has a normal looking eye and reflexes but they cant see!
- This visual change may go completely unnoticed by the pt
- homonymus hemanopsia - see half of vision on same side on each eye
posterior circulation CVA - vertebrobasilar CVA
- Ipsilateral eye, cranial nerve defects
- Contralateral motor defects
- Vertigo/ataxia, nausea/vomiting – this is the central cause of vertigo! This is what we are looking for with vertigo!
- Tinnitus/deafness, nystagmus
- LOC or ALOC, coma
posterior circulation CVA - basilar artery/pontine
-“locked-in” syndrome - can move the eyes but cant move any other muscle or body part
-Extensive motor deficit
Consciousness, eye movements spared
posterior circulation CVA - cerebellar strokes
- Central vertigo, vertical nystagmus
- Cranial nerve deficits
- Abnormal finger->nose, RRAM, etc
- Ataxia
lacunar infarcts
- HTN, DM
- Small vessels that perforate the deep, subcortical areas
- “pure” motor or sensory sx’s
- “clumsy hand” syndrome
- Persistent sx’s need w/u: CT, MRI
- Old, minor lacunar infarcts often seen incidentally on CT
- You will see these on CTs incidentally
- Whats the difference between TIA and lacunar stroke? Location (lacunar strokes are very deep inside the brain), the hallmark of TIAs is that it doesn’t leave a residual, so you cant see it on CT
NIHSS (national institutes of health stroke scale (abbreviated))
- By EMS and on arrival to ED – ALL stroke pt’s
- Provides info on:
- Location
- Severity
- Prognosis
- Initial score <15 better
- Initial score >20 not so good
- A must in communication with consultants
- Influences Tx decisions: tPA, transfer, etc
ED workup of stroke
- Recognition first, ABCDE’s, D-stick
- IV, O2, monitor, EKG, CBC (platelets), CMP PT/INR, troponin, utox, upreg
- NIHSS score
- CT brain non-con: then CTA (angiography) brain/neck if significant sx’s and ischemic
- Non-contrast may be normal for hours if ischemic
- Ischemic? No gross blood?
- Call Neurology/Stroke Team: tPA or are they candidate for interventional procedure?
- Hemorrhagic? Gross blood on CT?
- Call Neurosurgery
- D is for disability
- D-stick – it is one of the only things you need before giving tPA
- D-stick is dextrose or glucose stick
- CT is important!!! FIRST THING TO GET IS WITHOUT CONTRAST!! Is it ischemic or hemorrhagic?
- While the pt is in the CT, it is looked at – if it is ischemic (CT is negative for blood but sxs are significant), you get CTA of brain and neck
treatment of ischemic stroke
PRESERVE THE PENUMBRA
- Blood pressure control
- Avoid acute drop in BP. Raise BP if very low
- Tx BP if >220/120, MAP goal
- Labetolol, Nicardipine - easy to titrate IV
- Goal: situation/tPA or not/end-organ issues
- Aspirin
- To prevent recurrent event
- OK before thrombolytics
- Thrombolytics
- Maximize flow to penumbra
- Save brain tissue
- BP must be <185/110 for tPA
*Thrombectomy, advanced CT/MRI
- MAP = SBP + (2 X DBP) ÷ 3
- Normal MAP 70-110
- MAP can be higher in acute ischemic stroke (up to 120)
- Need at least MAP of 60 to perfuse coronary arteries
- TIME IS BRAIN
thrombolytics in ischemic stroke
tPA (Ateplase)
- <3-4.5hrs post sx onset
- Goal = door to tPA <60min (Stroke Center <30min)
- May improve outcome
- Hemorrhage risk
- Function, not life-saving
Who might benefit:
- Any adult over 18
- Anterior circulation stroke
- Moderate neuro deficit
- Known time of onset
- CT: no hemorrhage
Do NOT give it:
- ANY blood on CT, SAH
- Seizure at onset
- Hx hemorrhagic CVA
- Known tumor, AVN
- Very minor strokes
- Recent trauma, LP, arterial puncture*, surgery, GI bleed
- Can’t control BP
- On coumadin*, recent heparin, <1k platelets
Carotid Dissection
- Sudden onset ischemic stroke after trauma, neck manipulation, minor trauma
- Spontaneous: family hx, genetic, CAD
- HA, neck/face pain, partial Horner’s Syndrome, Cranial Nerve abnormalities
- Young w/ CVA or CN issues
- Diagnosis: CT angio of neck, MRI
Sickle cell
- > 20% (1 in 5) of patients with sickle cell disease have ischemic CVA’s by the age of 45
- Most common cause of stroke in children
- Think about ICB/SAH too
- Horner’s Syndrome = ptosis, miosis, anhydrosis
- Miosis = pupil constriction
- Mydriasis = pupil dilation
Treatment of hemorrhagic CVA
- ABCDE’s
- Control BP carefully
- Neurosurgical consult
- Multi-detector CT angiography/MRI
- After initial ED dx
Stroke Mimics
- Hypoglycemia – get a d-stick right away
- Seizure
- Prolonged post-ictal state, Todd’s paralysis
- Complicated migraine
- Sepsis
- Toxic/metabolic/neurologic conditions
- OD, Wernicke’s, peripheral neuropathy, demyelinating conditions, Lyme’s, etc
- Brain tumor or spinal cord tumor/met
- Isolated cranial nerve abnormalities
- Bell’s Palsy, 6th nerve palsy
- Functional (psych) disturbance
-Todd’s paralysis – prolonged partial or complete paralysis, usually unilateral, after a generalized seizure. Can last up to 36-48hrs
Transient Ischemic Attack
-Ischemia causing neuro deficit without infarct (official definition)
-Stroke-like symptoms lasting < 24 hours and usually 1-2hrs which completely resolve
-Risks same as CVA
TIA = risk for future CVA
-Risk of CVA measured in 2, 7, 30, 90 days
-Big risks, large vessel Dz, significant sx’s - all increase CVA risk
-ABCD2 score helps predict future stroke risk
-Age, BP, clinical features of TIA, duration, diabetes
-> or = 4: higher risk stroke in 2 days; higher score = greater risk
-Careful Hx and PE: thorough neuro exam, risk + sx pattern
Treatment of transient ischemic attack
- CT brain non-con first
- Should be normal if TIA
- O2, IV, monitor + d-stick
- Labs, EKG, PT/INR, troponin
- Aspirin (if no blood on CT)
- Workup also includes:
- Duplex US of carotids
- Echocardiography
- MRI brain
- CTA or MRA of neck vessels
- Admit/Observation unit:
- TIA w/ mod/high ABCD2, high risk pt
- “stuttering” or “crescendo” TIA
- Neurology consult
- Consider antiplatlet tx, anticoagulation for: moderate/high ABCD2 score, stuttering or crescendo TIA