Stroke presentation & investigation Flashcards

(43 cards)

1
Q

Why is prevention of stroke important to the NHS?

A

Commonest cause of long term disability in the UK

Patients who’ve had a stroke occupy 20% of NHS beds

Annual cost of over £5 billion treating stroke

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2
Q

What age demographic has the most strokes?

A

The elderly

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3
Q

Define what a stroke is

A

Clinical syndrome of sudden onset, causing a neurological deficit (loss of function)

Lasting more than 24 hours or until death

Of Vascular origin

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4
Q

Symptoms of a stroke are defined as being negative symptoms

What does this mean?

A

Symptoms are more to do with ‘loss of _______’

Symptoms of stroke:
Loss of power 
Loss of speech 
Loss of sensation 
Loss of vision 
Loss of coordination
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5
Q

Describe the clinical signs, on history/examination, that would indicate a stroke

A

Motor - clumsy/weak

Sensory loss

Speech - Dysarthria/dysphasia

Neglect / visuospatial problems

Vision - loss in one eye or hemianopia

Gaze palsy

Ataxia / vertigo / nystagmus

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6
Q

What is hemianopia?

A

Blindness over half the field of vision

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7
Q

What is gaze palsy?

A

Inability to move both eyes in the same direction

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8
Q

What is ataxia?

A

lack of voluntary coordination of muscle movements that can include gait abnormality, speech changes, and abnormalities in eye movements

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9
Q

What is nystagmus?

A

Dancing eyes

Rapid fluttery eye movements

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10
Q

What are the 2 types of causes of strokes?

A

Cerebral infarction

Haemorrhage

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11
Q

What are the 2 artery groups that supply the brain

A

Vertebral arteries (L & R)

Common carotid arteries (L & R)

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12
Q

What does the common carotid arteries split into?

A

Internal & external carotid arteries

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13
Q

What is the fate of the vertebral arteries?

A

Left and right vertebral arteries join together to form the single Basilar artery

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14
Q

What arteries branch off the Basilar artery?

A

Posterior inferior cerebellar arteries

Superior cerebellar arteries

Posterior cerebral arteries

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15
Q

What arteries make up the circle of willis?

A

Anterior communicating artery top

Anterior cerebral arteries

Internal carotid arteries/middle cerebral arteries

Posterior communicating arteries

Posterior cerebral arteries bottom

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16
Q

Most cerebral infarctions involve thrombus lodging in what arteries?

A

Middle cerebral arteries

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17
Q

The brain’s arterial supply can be thought of as an anterior and posterior circulation

What areas of the brain does the carotid system supply?

A

Anterior

The carotid system (via internal carotid arteries) supplies most of the hemispheres and cortical deep white matter

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18
Q

What areas of the brain does the vertebral artery system supply?

A

Posterior

Vertebro-basilar system supplies the brainstem, cerebellum and occipital lobes

19
Q

In the deep white matter of the brain, a small stroke can cause major deficits

Why?

A

In the deep white matter of the brain or in the pons, neural fibres from different areas of the brain run alongside each other in tight, internal capsules

A small stroke in this area will affect all these fibres thus have affect lots of different areas

20
Q

What are the causes of a ischaemic stroke (cerebral infarction)?

A

Large artery atherosclerosis:
- Typically in the carotid

Cardioembolic:
- Atrial fibrillation most common cause of this

Small artery occlusion - Lacunar

Less common:

  • Cryptogenic
  • Arterial dissection
  • Venous sinus thrombosis
21
Q

What are the causes of a hemorrhagic stroke?

A

Primary intracerebral haemorrhage:

  • Blood vessel bursting within the brain
  • Most common (70% HS’s)

Subarachnoid haemorrhage:
- Blood in the space around the brain

Arteriovenous malformation:
- Poorly formed blood vessels that ‘leak’

22
Q

What does a hemorrhagic stroke look like on a CT?

A

Darker grey area

Will extend to the peripheries if subarachnoid haemorrhage

23
Q

What is a lacunar stroke?

A

Happens when the small arteries to lacunae (gaps in the brain) are blocked

On a CT, it is a hard to see, slightly darker patch

On an MRI, it is a slightly lighter patch

24
Q

What is a carotid dissection?

A

When the intimal layer of a carotid artery separates from the media

Blood clot fills in the space

Can be idiopathic or caused by trauma

It is a rarer cause of cerebral infarction strokes (ischaemic stroke)

25
A patient presents with a stroke They have homonymous hemianopia What is this, and what is likely to have caused it?
They have lost half of the field of view in each eye Sight lost from the same side on both eyes A stroke in the left occipital cortex would cause the patient to lose the right half of the field of view of both the eyes
26
Clinically, strokes are classed into 4 subtypes according to the Oxford clinical stroke classification What are these?
TACS - total anterior circulation stroke PACS - partial anterior circulation stroke LACS - lacunar stroke - pure motor / pure sensory / sensorimotor POCS - posterior circulation stroke
27
A patient presents with: - Weakness - Sensory deficit - Homonymous hemianopia - Dysphasia (slurring) - Dyspraxia What type of stroke do they have?
TACS
28
A patient presents with: - Weakness of their left arm - Weakness of their left side of their face What type of stroke do they have?
Pure motor LACS "Complete or incomplete weakness in 1 side of the body in 2 of either the face, arm or leg"
29
A patient presents with: - Dysphasia - Dyspraxia What type of stroke is the patient having?
PACS (partial anterior) 2/3 of TACS criteria, basically the patient will have some signs of TACS but will be fine in other ways Ie - Weakness in limbs/face but still able to talk normally
30
A patient presents with: - Bilateral motor/sensory deficit - Disordered breathing - Tinnitus - Isolated homonymous hemianopia What type of stroke are they having?
POCS (posterior) POCS present with variable, unique symptoms Stuff like tinnitus, Horner's, coma, = POCS
31
A patient presents with: - Loss of feeling in the right arm and right leg What type of stroke are they having?
Pure sensory LACS
32
What is the most common subtype of stroke?
PACS (partial anterior) - 35%
33
TACS are usually caused by occlusion of what vessels ?
Proximal middle cerebral artery or Internal carotid
34
What causes PACS to happen?
More restricted cortical infarcts - occlusion of branches of middle cerebral artery
35
What areas of the brain are affected by POCS?
Brainstem, Cerebellum or Occipital lobes
36
Which is the most dangerous type of stroke?
TACS 60% mortality at 1 year
37
What is the one year prognosis for someone who survives a TACS?
Lowest recurrence of all subtypes at only 6% @ 1 year
38
What is the mortality and recurrence rate for PACS?
16% mortality in 1 year | 17% recurrence rate in 1 year high chance of recurrence in early stages
39
What is the mortality and recurrence rate for LACS?
11% mortality at 1 year 9% recurrence at 1 year
40
What is the mortality and recurrence rate for POCS?
19% mortality at 1 year 20% recurrence at 1 year (highest)
41
What are the risk factors for stroke?
``` Age Race (chinese most at risk) Family history Hypertension Atrial fibrillation ``` ``` Also: Smoking & alcohol Diet & Exercise Stress & Depression Diabetes Hyperlipidaemia & all that shite ```
42
Why is atrial fibrillation a risk factor for stroke?
Atrial fibrillation can cause a cardioembolic ischaemic stroke
43
Which gender is most at risk of a stroke?
In adult to early old age (<75) - men are more at risk In > 75 age group, women are more at risk