Structure and Function of the Cell Membrane Flashcards

Lecture 15 (45 cards)

1
Q

what are the two main components of cell membranes?

A

phospholipids and proteins

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2
Q

what structural property makes phospholipids form bilayers in water?

A

their amphipathic nature

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3
Q

which part of the phospholipid is hydrophobic?

A

the fatty acid tails

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4
Q

which part of the phospholipid is hydrophilic?

A

the polar head groups

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5
Q

what model describes the dynamic and fluid nature of the membrane?

A

the fluid mosaic model

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6
Q

what affects membrane fluidity?

A

cholesterol content and temperature

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7
Q

what is selective permeabilty?

A

the ability of the membrane to regulate which substances can cross it

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8
Q

what types of molecules diffuse easily through the lipid bilayer?

A

small, non-polar, lipid-soluble molecules

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9
Q

what’s osmosis?

A

the passive net movement of water across a semi-permeable membrane

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10
Q

what’s tonicity?

A

how a solution affects cell volume based on solute permeability

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11
Q

what’s the role of aquaporins?

A

to facilitate rapid osmotic water transport

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12
Q

what defines an integral membrane protein?

A

it spans the lipid bilayer and is amphipathic

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13
Q

how do peripheral proteins interact with the membrane?

A

via non-covalent interactions with integral proteins or lipids

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14
Q

what is membrane potential?

A

a voltage across the membrane due to ion gradients

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15
Q

what percentage of resting cell energy maintains ion gradients?

A

approximately 30%

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16
Q

why is membrane fluidity important for cell function?

A

enables protein movement, signal transduction, and membrane reshaping for processes like endocytosis

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17
Q

how does cholesterol act as a membrane fluidity buffer?

A

it prevents excessive fluidity at high temperatures and rigidity at low temperatures

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18
Q

why can’t charged ions freely cross the phospholipid bilayer?

A

the hydrophobic core is highly impermeable to charged particles

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19
Q

what’s the importance of asymmetric lipid distribution?

A

it affects membrane curvature and protein signalling

20
Q

how does diffusion differ from osmosis?

A

diffusion is the movement of solutes; osmosis is the movement of water

21
Q

why do RBCs lyse in hypotonic solutions?

A

water enters the cell due to osmotic imbalance, causing swelling and bursting

22
Q

how does the membrane maintain homeostasis?

A

by regulating substance entry and exit, and maintaining ion gradients

23
Q

why do larger molecules diffuse slower than smaller ones?

A

because of greater mass and resistance

24
Q

how is ATP involved in membrane transport?

A

it powers pumps that maintain ion gradients like Na+/K+ ATPase

25
what happens to water movement if solutes can cross the membrane?
the tonicity effect is reduced or becomes nullified
26
why is 'flip flop' of lipids rare?
because it requires significant energy to move hydrophilic heads through the hydrophobic core
27
how do membrane proteins assist impermeable molecules?
through channels or transporters that facilitate or actively move them across
28
what causes crenation in cells?
exposure to hypertonic solutions, leading to water loss and shrinkage
29
what role does membrane potential play in nerve function?
it enables the transmission of electrical signals along neurons
30
why are membranes compared to capacitors?
because they store electrical charge by separating ions across the bilayer
31
the ___ model describes the membrane as a fluid structure with proteins embedded in or attached to a bilayer of phospholipids
fluid mosaic
32
phospholipids form a bilayer in aqueous environments due to their ___ nature
amphipathic
33
the ___ heads of phospholipids face the aqueous environments inside and outside the cell
hydrophilic (polar)
34
the membrane is most permeable to ___ molecules like O2, N2, and steroids
small nonpolar
35
movement of water form a hypotonic to a hypertonic solution is called ___
osmosis
36
___ is the minimum pressure required to prevent osmosis
osmotic pressure
37
cholesterol ___ membrane fluidity at low temperatures, and ___ it at high temperatures
increases; decreases
38
membrane proteins that span the bilayer and are amphipathic are called ___ proteins
integral
39
peripheral proteins are attached to membrane surfaces through ___ interactions
non-covalent
40
only ___ solutes contribute to tonicity
non-penetrating
41
ATP-powered pumps maintain ion gradients by using energy from ___
ATP hydrolysis
42
the ___ gradient combines both concentration and electrical gradients
electrochemical
43
in the cell membrane, ___ fatty acids increase fluidity by preventing tight lipid packing
unsaturated
44
the property that allows lipids and proteins to move within the membrane plane is called ___
lateral diffusion
45
diffusion is a ___ process that doesn't require cellular energy
passive