Structure and Function of the Cell Membrane Flashcards
Lecture 15 (45 cards)
what are the two main components of cell membranes?
phospholipids and proteins
what structural property makes phospholipids form bilayers in water?
their amphipathic nature
which part of the phospholipid is hydrophobic?
the fatty acid tails
which part of the phospholipid is hydrophilic?
the polar head groups
what model describes the dynamic and fluid nature of the membrane?
the fluid mosaic model
what affects membrane fluidity?
cholesterol content and temperature
what is selective permeabilty?
the ability of the membrane to regulate which substances can cross it
what types of molecules diffuse easily through the lipid bilayer?
small, non-polar, lipid-soluble molecules
what’s osmosis?
the passive net movement of water across a semi-permeable membrane
what’s tonicity?
how a solution affects cell volume based on solute permeability
what’s the role of aquaporins?
to facilitate rapid osmotic water transport
what defines an integral membrane protein?
it spans the lipid bilayer and is amphipathic
how do peripheral proteins interact with the membrane?
via non-covalent interactions with integral proteins or lipids
what is membrane potential?
a voltage across the membrane due to ion gradients
what percentage of resting cell energy maintains ion gradients?
approximately 30%
why is membrane fluidity important for cell function?
enables protein movement, signal transduction, and membrane reshaping for processes like endocytosis
how does cholesterol act as a membrane fluidity buffer?
it prevents excessive fluidity at high temperatures and rigidity at low temperatures
why can’t charged ions freely cross the phospholipid bilayer?
the hydrophobic core is highly impermeable to charged particles
what’s the importance of asymmetric lipid distribution?
it affects membrane curvature and protein signalling
how does diffusion differ from osmosis?
diffusion is the movement of solutes; osmosis is the movement of water
why do RBCs lyse in hypotonic solutions?
water enters the cell due to osmotic imbalance, causing swelling and bursting
how does the membrane maintain homeostasis?
by regulating substance entry and exit, and maintaining ion gradients
why do larger molecules diffuse slower than smaller ones?
because of greater mass and resistance
how is ATP involved in membrane transport?
it powers pumps that maintain ion gradients like Na+/K+ ATPase