Study Aid Test Questions

Question 1

Sites of hemopoiesis (conception-adult)

Answer 1

0-2 months: blood cells formed in the yolk sac;
2-7 months: liver and spleen
5-9 months: bone marrow
Infant-childhood: ~50% marrow
Adult: Skull, vertebral column (ribs and sternum), sacrum, pelvis, proximal femurs

Question 2

Cytoskeleton composed of what in erythrocyte?

Answer 2

Alpha and Beta spectrin

Question 3

Pokiliocytes: mean, reflect, suggest what is taking place?

Answer 3

Suggest Hemopoiesis

Question 4

Normal RBC count

Answer 4

Overall: 3.6-5.4

Question 5

Cause for primary erythrocytosis?

Answer 5

Polycythemia vera: hyperplasia within marrow, but don’t know why

Question 6

Explain what increase in RBC count suggests?

Answer 6

Primary: Polycythemia vera

Question 7

Cause for relative erythrocytosis

Answer 7

Dehydration, overuse of diuretics

Question 8

Abnormal erythrocyte sites: term used that cells have abnormal sizes

Answer 8

Anisocytosis: RBC is of unequal size; suggests anemia

Question 9

Most logical/ reasonable explanation for erythropenia?

Answer 9

Anemia: especially patients with RH

Question 10

Given reticulocyte count of 5% suggests what?

Answer 10

Hemolytic anemia

Question 11

Normal reticulocyte index

Answer 11

1

Question 12

Normal hematocrit

Answer 12

Overall: 36-52

Question 13

Packed cell volume of 30%

Answer 13

Low for both M/F –> anemia, leukemia cirrhosis, hyperthyroidism

Question 14

Increased Hct reflects what?

Answer 14

increase in altitude, polycythemia, SEVERE DEHYDRATION, shock

Question 15

Know normal range of Hb and difference between male and female

Answer 15

OVERALL: 12-17.4
Male: 14-17.4 gm%
Female: 12-16 gm%

Question 16

Lab tests evaluate degree of anisocytosis (not the same size)

Answer 16

RDW Tests

Question 17

Mean corpuscular volume (MCV) level means?

Answer 17

100-160: macrocytic anemias, large volume (B12, or folic acid deficiency)

Question 18

What may affect HbA level

Answer 18

Nothing, glucose levels?

Question 19

HbH1c levels suggest diabetic patient in different volumes of control?

Answer 19

7% = good controls
10% = fair
13-20% = poor

Question 20

Glycolcilia Hb levels decrease 4%

Answer 20

Chronic renal failure since kidney can no longer produce erythropoietin

Question 21

Cause of microcytic normochromic anemia?

Answer 21

Renal disease: not producing erythropoietin

Question 22

Features of Plummer-Vinson Syndrome?

Answer 22

Koilonychia: spoon shaped nails

Question 23

Labs in early stages of IDA?

Answer 23

Increase # of platelets

Question 24

Which anemia has golf ball cells in stain?

Answer 24

Alpha-thalacemia (with cresol stain)

Question 25

What are labs for patient with alpha-thalacemia?

Answer 25

Microcytic hypochromic

Question 26

Physical and lab features of patient with severe Cooley's anemia?

Answer 26

(PAS doesn't indicate???) Life threatening, growth failure and growth deformities

Question 27

Causes of alpha-thalacemia?

Answer 27

HbH Affinity to O2

Question 28

Anemia that produces hypoplasia or absence of thumbs?

Answer 28

Fanconi's anemia

Question 29

What are labs of patient with severe B12 deficiency?

Answer 29

a. Anicytosis, pequiliocytosis b. Macrocytic and normochromic c. If B12 serum levels are

Question 30

What are labs of patient with severe folic acid deficient anemia?

Answer 30

Macrocytic, normochromic (like B12)

Question 31

Lab tests that screen HbS?

Answer 31

Sickledex Solubility prep

Question 32

Abnormal RBC suggest hypospleenism

Answer 32

Target cells and giant bodies: spleen cannot handle these morphologies

Question 33

Labs for patient with sickle cell disease?

Answer 33

HbS

Question 34

Presence of >3% stab cell in leukocytosis suggests?

Answer 34

Shift to the left (neutrophilia)

Question 35

Downey cells

Answer 35

Lymphocytes of infections

Question 36

Cause for lymphopenia?

Answer 36

Post chemo or radiation therapy or an immunosuppressant

Question 37

What leukemia's most common for adults?

Answer 37

CLL: Chronic Lymphocytic Leukemia (over 50)

Question 38

Leukomoid reaction

Answer 38

is not progressive/ permanent

Question 39

ESRs using tubes: if reads 20 mm in 1 hour: suggests?

Answer 39

No alteration of plasma proteins

Question 40

Normal value for C-reactive protein?

Answer 40

0.7 is the answer on exam