Subarachnoid haemorrhage Flashcards

(35 cards)

1
Q

Define a Subarachnoid Haemorrhage

A

presence of blood within the subarachnoid space, i.e. deep to the subarachnoid layer of the meninges

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2
Q

What two layers of the brain does blood sit between in a Subarachnoid Haemorrhage?

A

pia mater and arachnoid membrane

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3
Q

What are two ways we can classify a Subarachnoid Haemorrhage?

A

Spontaneous (70%)

Traumatic (30%)

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4
Q

What are some RF for a Subarachnoid Haemorrhage?

A

Smoking
HTN
excessive alcohol
Cocaine use
FHx

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5
Q

Which patients is a Subarachnoid Haemorrhage more common in?

A

Female pts
Black pts
Age 45-70yrs

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6
Q

Subarachnoid Haemorrhage is particularly associated with what conditions …?

A

Sickle cell anaemia

CT disorders - Marfans / Ehlos Danlos / APKD / coarctation of aorta (aneurysms)

Neurofibromatosis

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7
Q

List some causes of a spontaneous Subarachnoid Haemorrhage

A

Intracranial aneurysms

Arteriovenous malformation

Pituitary apoplexy

Arterial dissection

mycotic (infective aneurysms)

Perimesencephalic (idiopathic venous bleed)

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8
Q

What are the presenting features of a Subarachnoid Haemorrhage?

A

Headache: sudden onset, THUNDERCLAP

Nausea & vomiting

Meningism (neck stiffness / photophobia

back pain

Syncope / Coma

Seizures

Sudden death

ECG: ST elevation

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9
Q

Name and describe 2 physical tests which can demonstrate meningismus in Subarachnoid Haemorrhage?

A

Kernig sign:
Flex knee to 90 degrees >
Hip flexed to 90 degrees > Extend knee - elicit pain

Brudzinski sign:
Patient lies supine > flex neck > elicit knee flexion

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10
Q

What focal neurological signs might you see in a pt with Subarachnoid Haemorrhage?

A

Hemiparesis

Occulomotor nerve palsy

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11
Q

What clinical signs in the eye might you see in a pt with Subarachnoid Haemorrhage?

A

Retinal haemorrhage

Papilloedema - blurring of borders of optic disc

Isolated complete III-nerve palsy. *

  • secondary to compression by a posterior communicating artery (PCOM) aneurysm or / damage to the nerve due to blood in the subarachnoid space
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12
Q

What Investigations would you do for a pt with Subarachnoid Haemorrhage?

A

CT
1. W/in 6 hours: non contrast CT brain - show hyperdense blood ( if normal- no LP )
2. Outside 6 hours: Non contrast CT brain - if normal DO LP

LP / CSF
Performed 12 hours after onset of symptoms - xanthchromia

After SAH confirmed: looking for a cause

CT Angiography- for cause e.g. aneurysm / AVM

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13
Q

What are the benefits of doing a CT brain for a pt with Subarachnoid Haemorrhage?

A

Quick - 30 mins

Blood distribution can indicate site of aneurysm

Detect early hydrocephalus

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14
Q

What time frame is optimal to CT scan a pt with suspected Subarachnoid Haemorrhage?

A

w/in 6 hours = 100 % sensitivity

> 1 week = 50%

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15
Q

What will CT of brain show in a patient with Subarachnoid Haemorrhage?

A

Will see hyperattenuation due to fresh clots.

Acute blood is hyper-dense / bright on CT

Often see blood in basal cisterns, sulci, ventricular system.

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16
Q

Where should pts with Subarachnoid Haemorrhage be managed?

A

Specialist neurosurgical unit

17
Q

When would you order a LP for a patient with a suspected Subarachnoid Haemorrhage? ?

A

Confirm SAH if CT is negative (no blood seen in 7% pts)

at least 12 hours after onset of symptoms to allow for xanthochromia (up to 1 week)

18
Q

What findings are you looking for in a LP to confirm a Subarachnoid Haemorrhage? ?

A
  • Xanthochromia- RBC breakdown. (distinguishes SAH from ‘traumatic tap’)
  • normal or raised opening pressure
  • blood stained
  • lymphocytic reaction
  • elevated protein
19
Q

What are some predictive factors in Subarachnoid Haemorrhage?

A

consciousness
CT Scan

20
Q

How should you ensure a pt with an aneurysm is kept before treatment to prevent re-bleed of Subarachnoid Haemorrhage?

A

strict bed rest
controlled BP
No straining e.g. toilet

21
Q

What kind of MRI is useful for imaging Subarachnoid Haemorrhage?

A

Echo gradients show haemosiderin (black blob)

T2 FLAIR - increased T2 signal = blood (T2 shows water as white)

(Burton, Dr said “2 ladies drinking tea with a dash of milk” to remember this)

22
Q

When would Angiography be performed and why in the context of a Subarachnoid Haemorrhage?

A

To understand causative pathology :

e.g. CT intracranial angiogram for vascular lesion such as aneurysm or AVM

23
Q

What surgical intervention can be used for Subarachnoid Haemorrhage?

A

Coil
- interventional radiologist
- endovascular approach> catheter into arterial system> platinum coil into aneurysm, sealing it off from artery.

Clipping
- neurosurgeon
- craniotomy and clipping off the anueurysm

24
Q

Where should pts with Subarachnoid Haemorrhage be managed?

A

Specialist neurosurgical unit

Immediate referral once SAHis confirmed

25
Why is vasospasm so dangerous in the context of Subarachnoid Haemorrhage?
cause mortality / neurological sequelae Vasopasm is delayed often day 4-14 after SAH Break down of blood products accumulating in subarachnoid causes irritation to the artery walls. Vasospasm narrows lumen of artery reducing blood flow and causing ischaemia
26
What is used to prevent vasospasm for Subarachnoid Haemorrhage?
Nimodipine (calcium channel inhibitor working on brain vessels) 21 day course
27
How is hydrocephalus treated in Subarachnoid Haemorrhage?
Short term: External ventricular drain (CSF diverted to bag bedside bedside) Long term: Ventriculo-peritoneal shunt
28
What are complications of an aneurysmal Subarachnoid Haemorrhage?
Re-bleeding (most common in first 12 hours > neuro symptoms? new CT please) Vasospasm Hyponatreamia (SIADH) Seizures Hydrocephalus Death
29
What are some predictive factors in Subarachnoid Haemorrhage?
conscious level on admission age amount of blood visible on CT head
30
How should you ensure a pt with an aneurysm is kept before treatment to prevent re-bleed of Subarachnoid Haemorrhage?
strict bed rest controlled BP No straining e.g. toilet to prevent re-bleed
31
What is involved in invasive angiography for Subarachnoid Haemorrhage?
DSA - Digital subtraction angiography (catheter angiogram) Endovascular coiling is done at same time
32
What is involved in non-invasive angiography for Subarachnoid Haemorrhage?
CTA MRA
33
What ECG changes could you see on a pt with Subarachnoid Haemorrhage?
ST elevation can be seen
34
Pts who have reduced consciousness and a Subarachnoid Haemorrhage might need what?
Intubation and ventilation
35
What support is needed from the multidisciplinary team for treatment of Subarachnoid Haemorrhage?
Nursing Nutrition physio occupational therapy