Substance use d/o

Question 1

When do you use disulfiram for UAD?

What’s its other name and MOA?

Answer 1

Aka Antabuse
in a pt who’s super motivated and willing to be anbstinent. B/c you can easily skip a dose and drink
MOA: inhibits alcohol dehydrogenase and makes you feel sick

Question 2

What medications are considered first line in moderate-severe AUD?

Answer 2

Naltrexone and acamprosate

Question 3

MOA acamprosate

Answer 3

It’s a glutamate modulator

Question 4

Benzo withdrawal

Answer 4

Tachycardia, inc in BP, hyperpyrexia
Anxiety, panic attacks, irritability, restlessness, insomnia
DELIRIUM and Psychosis
Tremors, seizures, rarely death

Question 5

What RR should you really start to worry is opiate overdose?

Answer 5

The best predictor of acute toxicity is a respiratory rate <12/min as opioids act directly on brainstem respiratory centers to produce respiratory depression