Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

MICRO ADYA > Summary antibiotic table- from notion (+ BACTERIA CLASSIFICATION) > Flashcards

Summary antibiotic table- from notion (+ BACTERIA CLASSIFICATION) Flashcards

1
Q

Which ABX are within cell wall inhibitors?

A
  1. Beta lactams
  2. Glycopeptdies
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Examples of beta lactams

A

Penicillins

Carbapenams

Cephalosporins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is penicillin active against?

A

Gram positives except staph aureus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is amoxicillin effective against

A

Gram positives, enterococci, gram negative, not staph aureus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is flucloxacillin active against?

A

Staph aureus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is piperecillin active against

A

Pseudomonas

Non-enteric gram negatives

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are the different generations of cephalosporins? And how does their activity change as generation goes up?

A

Activity against gram negatives increases over generation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are carbapenams active against

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Examples of glycopeptide antibiotics

What type of bacteria are they active against?

A

Vancomycin

Teicoplanin

Only active against gram positives- they are too large to cross the cell wall of gram negative organisms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is vancomycin active against

A

Gram positives, MRSA, C difficile (PO)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is teicoplanin active against?

A

Gram positives, MRSA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which ABX inhibit protein synthesis

A

Aminoglycosides

Tetracycline

macrolides

Chloramphenicol

Oxalozidinediones

(TAMCO)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Examples of aminoglycosides

A

Gentamicin

Tobramicin

Amicakin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is gentamicin active against

A

Pseudomonas

MDR (multi-drug resistant organisms)

ESBL organisms

**path guide: gram negative sepsis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What drug regimen is used against pseudomonas?

A

Piperecillin and gentamicin

(broad spectrum penicillin + aminoglycoside)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Where are beta lactams excreted

A

Renally

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What are examples of CPE?

A

Carbapenam resistant enterococci

Examples- acinetobacter

Klebsiella

These are multidrug resistant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What must you be cautious wrt to glycopeptides

A

Nephrotoxic - monitor drug levels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Key points about aminoglycosides

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Examples of tetracyclines and what are they active against?

A

**intracellular pathogens such as chlamydia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Who should you not give tetracyclines to?

A

Children and pregnant women

Because they deposit in bone and discolour teeth

Also they are folate antagonists so can’t give pregnant women

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Which ABX are in the MSL group?

A

Macrolides

Streptogramins

Lincosamides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What are macrolides used to treat?

What are they NOT active against?

A
  1. Staph and strep infections if resistance to penicillin
  2. Legionella pneumophilia
  3. Camylobacter

**not active against gram negatives (except azithromycin)

Basically: gram positive (in cases of penicillin allergy) and atypical pneumonia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

What is azithromycin used to treat?

A

Salmonella infection

rmb it is second line in salmonella typhi infection after ceftriaxone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
What is chloramphenicol used for?
bacterial conjuncitivitis
26
What are the risks of chloramphenicol?
Grey baby syndrome Aplastic anaemia
27
Example of oxalozidinediones?
Linezolid
28
What is linezolid used for?
Gram positives- including VRE and MRSA NOT active against gram negatives
29
What are the risks of linezolid?
30
Which ABX inhibit DNA synthesis?
Quinolones Nitromidazoles Nitrofurans
31
Examples of quinolones
32
Key points about quinolones
\*\*active against gram negatives
33
Examples of nitromidazoles and key points
34
Example of nitrofurans and key points
35
Examples of rifamicins
Rifampicin Rifabutin
36
What is rifampicin active against
37
Can you use rifampicin on its own?
No must give it with another drug eg in TB and in prosthetic infections can only be used on its own as prophylaxis for meningitis for short term
38
Where is rifamipicin metabolised and what does it interact with?
Metabolised in the liver Interacts with COCP
39
What happens to urine when you take rifampicin?
Urine turns orange
40
Which antibiotics are cell membrane toxins?
polymyxins- eg collistin cyclic lipopeptide eg Polymyxin
41
What is daptomycin active against?
Gram positives MRSA VRE
42
Key points about polymyxins
43
Which abx inhibit folate metabolism
44
Summary of drugs active against gram positives
45
Summary of drugs active against gram negatives
46
47
48
What is VRE?
Vancomycin resistant enterococcus
49
Which antibiotics are broad spectrum?
Co-amoxiclav (amoxicillin + clavulanic acid), tazocin (piperacillin + tazobactam), ciprofloxacin, meropenem
50
Which drugs are narrow spectrum?
flucloxacillin, metronidazole, gentamicin
51
Four mechanisms of antibiotic reisstance
52
Typical antibiotic used for staph aureus in skin
flucloxacillin unless allergy
53
Typical antibiotic used in pharyngitis
pathogen: B haemolytic strep antibiotic: benzylpenicillin
54
Typical antibiotic for CAP
Mild: amoxicillin Severe: co-amoxiclav + clarithromycin
55
Abx for HAP
Co-amoxiclav + gentamicin OR tazocin \*\*\*DOUBLE CHECK WITH THE LECTURE\*\*\*
56
Empirical treatment for sepsis
57
Summary antibiotic table: path guide
58
Common bugs and treatment
59
Summary table for types ofb acteria
60
Classification of strep bacteria
61
Classification of gram positvie bacteria
62
Summary of the gram positive resistant organisms and how to treat them
63
if you find mrsa on skin what does that mean?
could just be contamination - don't treat with abx do decontamination with chlorhexidine wash and nasal mupirocin
64
What are the ESBL producing gram negative organisms and how do you treat them?
65
How do you treat cellulitis?
first line: flucloxacillin 2nd line if penicillin allergic: clarirthomycin or erythromycin (if pregnant)

MICRO ADYA (22 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions