Superficial Mycoses Flashcards Preview

Infectious Disease Part II > Superficial Mycoses > Flashcards

Flashcards in Superficial Mycoses Deck (14)
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1
Q

in many cases a specific diagnosis can be made based on fungal ________ in tissue, so skin scrapings or biopsies are best method

A

morphology

2
Q

unicellular form of fungi, reproduce by budding

A

yeast

3
Q

multicellular filamentous colonies

A

molds

4
Q

branching structures of molds

A

hyphae

5
Q

both mold and yeast forms

A

dimorphic

6
Q

the fruiting body characteristic of molds, which disseminates spores, used to classify molds

A

conidiaphore

7
Q
  • occurs on head/scalp
  • associated with lymphadenopathy, alopecia, scaling
  • ectothrix: fungal spores and hyphae cover outside of hari
  • endothrix: invasion, hair shaft filled with fungal branches, do not fluoresce with Wood’s light (blue histo pic)
A

tinea capitus

8
Q
  • nail infection in elderly
  • treat with metholatum deep heating rub and oral drugs
  • red (rubrum) on underside, white colonies
  • microconidia instead of macroconidia
A

trichophyton rubrum

9
Q
  • causes candidiasis, most common cause of fungal infection
  • intertrigo (skin folds), paronychia (nail bed), diaper rash, vulvovaginitis, thrush (oral), esophagitis, systemic in immunocompromised
  • commensal fungus
  • stains with calcifluor white
A

candidiasis (yeast infection)

10
Q
  • oral candidiasis, white patches can be scraped off, common in HIV patients
  • biofilm protection and adherence
  • calcifluor white - fluroescent, pesudohyphae indicate invasion and budding
  • PAS stain: bright pink/magenta
A

thrush, oral candidiasis

11
Q
  • causes sporotrichosis, found on roses, can have extensive spread
  • dissemination to lungs, in AIDS patients
A

sporothrix schenckii

12
Q
  • chronic skin infection from fungi in soil and decaying vegetables
  • copper penny stain, sclerotic bodies
A

chromomycosis (fonsecaea pedrosi)

13
Q
  • dimorphic, Mississippi and Ohio rivers, great lakes
  • disturbance of soil - infectious aerosols - inhalation or broken skin
  • abrupt productive cough, headache, chest pain, fever, abdominal pain, upper lobes
  • large base budding yeasts with double contours, granulomas with yeast inside giant cells, epithelial hyperplasia, Calcifluor white and PAS
A

blastomyces dermatitidis

14
Q

treatment for superficial fungal infections?

A
  • OTC miconazole
  • nails: griseofulvin
  • systemic anti fungals in complicated cases, dimorphic always require systemic