surface markers Flashcards
(18 cards)
involved on T cell activation
CD2
found on all T cells; associated with T cell antigen receptor
CD3
identifies T helper cells; also found on most T regulatory cells
CD4
receptor for HIV; co receptor for MHC class II
CD4
positive or negative modulation of T and B cell receptor signaling
CD5
identifies cytotoxic T cells
CD8
co receptor for MCH class I
CD8
protease; marker for pre-B CALLA
CD10
low affinity Fc receptor for antibody; mediates phagocytosis
CD16
part of B cell co receptor; regulates B cell development & activation
CD19
receptor for complement component C3d; part of B cell co receptor with CD19
CD21
regulation of IgE synthesis; triggers release of GM-CSF from monocytes
CD23
receptor for IL2
CD25
adhesion molecule mediating homing to peripheral lymphoid organs
CD44
essential in T & B cell antigen stimulated activation
CD45R
cell adhesion & signaling
CD45
subunit of NKG2-A complex involved in inhibition of NK cell cytotoxicity
CD94
normal ratio of CD4 & CD8 cells
2:1