Surgery (Vasc, Colo, UGI, Breast...) Flashcards
(43 cards)
Anastrozole
- Class of drug?
- Indication (and why)?
- Main risks?
- Any pre-investigations required?
Anastrozole
- Aromatase Inhibitor
- Treatment of ER +ve breast CA in postmenopausal women - aromatisation accounts for majority of oestrogen in postmenopausal women
- Osteoporosis, arthralgia, myalgia
- DEXA scan - due to osteoporosis risk
Tamoxifen
- Class of drug?
- Indication?
- Risks?
Tamoxifen
- Selective Oestrogen Receptor Modulator (SERM) - Antagonist and partial agonist
- ER +ve breast CA
- VTE risk, endometrial CA, menstrual disturbance, hot flushes
- What are the two main sub-types of testicular CA?
2. Which has a worse prognosis?
- Seminomas and teratomas
2. Teratomas
Risk factors for testicular CA?
Infertility
Cryptorchidism
Family history, mumps orchitis
Klinefelter’s syndrome
Presenting features of testicular CA?
Testicular lump - painless
Hydrocoele
Gynaecomastia
Testicular CA - tumour markers?
hCG
AFP
Testicular CA
- Diagnosis?
- Treatment?
Testicular CA
- USS
- Orchidectomy +/- RT, chemo
Peripheral Arterial Disease - Management
- Conservative measures?
- Drugs for all patients (2)?
- Last-line drug for patients with poor QoL?
- Stop smoking, exercise, treat co-morbidities
- Statin & Clopidogrel
- Naftidrofuryl oxalate (vasodilator)
Aortic Dissection
- Presentation?
- Associations / risk factors?
- Classification?
- Imaging of choice?
Aortic Dissection
1. Tearing chest pain to back, weak pulses, HTN
2. HTN, Trauma, Marfan’s, Pregnancy
3. Type A = ascending aorta
Type B = descending aorta distal to L subclavian
Ascending Cholangitis
- Main bug?
- Name of classical triad?
- 4 features of triad?
- Diagnostic modality?
- Treatment?
Ascending Cholangitis
- E Coli
- Charcot’s Triad
- RUQ pain, fever, jaundice, raised inflammatory markers
- USS
- IV Abx, ERCP 24-48hrs after presentation to relieve obstruction
Colorectal CA Referral Criteria?
Unexplained weight loss and abdo pain >40
Unexplained PR bleed >50
IDA or change in bowel habit >60
+ve FIT
Faecal Immunochemical Test (FIT)
1. Screening details?
FIT
1. 60-74yo, or suspicion of bowel CA due to symptoms not quite meeting 2ww criteria
Renal Stones
- Diagnostic Modality?
- Drugs can give in ED?
- Drugs can give for medical management?
Renal Stones
- CT KUB
- Diclofenac
- Tamsulosin (alpha-blocker)
Renal Stones - Management What management option in the following? 1. Emergency (obstruction, previous transplant, infection) 2. Stone 2-5mm, non-pregnant? 3. Stone 2-5mm, pregnant? 4. Stone <5mm 5. Stone complex / staghorn calculus?
Renal Stones - Management
- Emergency = nephrostomy / stent to decompress
- 2-5mm and non-pregnant = shock wave lithotripsy
- 2-5mm and pregnant = ureteroscopy
- <5mm = conservative (Tamsulosin, watch and wait)
- Complex = percutaneous nephrolithotripsy
Chronic Pancreatitis
- Classic presentation?
- Risk factors?
- How to look for exocrine dysfunction?
- Imaging modality and finding?
- Treatment?
Chronic Pancreatitis
- Pain after fatty meal + steatorrhoea + diabetes
- Alcohol, CF, ductal obstruction
- Faecal elastase
- CT (calcification)
- Pancreatic enzyme supplement, analgesia, stop EtOH, treat obstruction
Acute Wound Dehiscence - Immediate Management (3 steps)
- Cover with saline-soaked gauze (prevent fluid loss)
- IV Abx
- Senior +/- theatre
Haemorrhoids
- Grading (1-4)?
- Treatment?
Haemorrhoids
1. Grade I - no prolapse
Grade II - prolapse on defaecation, spontaneously reduce
Grade III - manually reduce
Grade IV - cannot reduce
2. Fibre, local anaesthetics and steroids, rubber band ligation
Priapism
- Definition?
- Classification, which is more dangerous?
- Investigations?
- Treatment?
Priapism
- Erection >4hrs not related to sexual stimulation
- Ischaemic (more dangerous, impaired vasorelaxation), non-ischaemic (less dangerous, high arterial inflow, e.g. congenital)
- Cavernosal blood gas analysis, Doppler USS in young children
- Aspirate blood from cavernosa / surgery
Breast CA Screening
- Screening Details?
- Criteria for referring for familial breast CA screening?
- Referral for non-screening referral?
Breast CA Screening 1. 50-70y, every 3y 2. 1st/2nd degree relative +one of: Age>40 B/L breast CA Paternal side breast CA Hx Male breast CA Ovarian CA Sarcoma in <45y Jewish heritage 3. Age >30 and unexplained lump Age >50 and nipple changes
Volvulus
Which type of volvulus:
1. 80% cases, large bowel
2. 20% cases, small bowel
Volvulus
- Sigmoid
- Caecal
Breast CA
- Most common sub-type?
- What is Paget’s disease of the nipple?
Breast CA
- Invasive ductal carcinoma
- Eczematous changes around the nipple, indicative of CA
Breast CA - Management
- When mastectomy?
- When WLE?
- Adjuvant therapy?
- Hormone therapy: when indicated?
- Hormone therapy: pre-menopausal?
- Hormone therapy: post-menopausal?
- S/Es of SERMs?
Breast CA - Management
- Multifocal, central, large lesion, DCIS >4cm
- Solitary, peripheral, small lesion, DCIS <4cm
- RT for WLE / mastectomy if T3/4 or >4 nodes
- ER+ve breast CA
- Pre-menopausal = Tamoxifen (SERM)
- Post-menopausal = Anastrozole (Aromatase Inhibitor)
- VTE, endometrial CA, menopausal symptoms
Hernias
- Inguinal location?
- Femoral location?
- Which has higher rates of strangulation?
Hernias
- Supero-medial to pubic tubercle
- Infero-lateral to pubic tubercle
- Femoral
Hernias
- Define incarceration
- Define strangulation
Hernias
- Cannot reduce, risk of strangulation
- Tender, systemically unwell, surgical emergency