Syndrome paranéoplasique Flashcards

(38 cards)

1
Q

Ganglionnopathie paraneoplasique

A

Anti Hu et anti crmp5

surface

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2
Q

myasthénie grave

A

anti Rach, antiMuSK, antiLRP4

surface

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3
Q

neuropathy autonomique : anticorps et cancer

A

anti RaCH, alpha-3 ganglionic , adenocarcinome

surface

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4
Q

anti récepteur AMPA : syndrome et cancers

A

encephalite limbique : tumeurs thymique, SCLC, cancer du sein

surface

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5
Q

NMO : anticorps et cancer associé

A

Anti aquaporine 4 : thymome, cancer du poumon, cancer du sein

surface

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6
Q

Neuromyotonie /syndrome de Morvan : anticorps et cancer

A

CASPR2 , thymome

surface

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7
Q

DPPX : syndrome clinique et cancer

A

encephalite bas grade, hyperexcitabilité SNC, syndrome du tronc cerebral, ataxie perte de poids et diarrhée, associé à néo hématologique

surface

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8
Q

Anti GABA A, syndrome et cancer

A

lésion cortical et sous cortical, status epileptique
thymome

surface

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9
Q

Anti GABA B : syndrome et cancer

A

encephalite limbique, status epileptique

SCLC

surface

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10
Q

anti Gly : syndrome et cancer

A

progressive encephalomyelitis with rigidity and myoclonus (PERM)

stiff person syndrome

Thymome

surface

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11
Q

IgLON5 : syndrome et cancer

A

Sleep disorders, symptômes bulbaire, désordre de la marche, peut mimer PSP

adenocarcinome

surface

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12
Q

convulsion dystonique brachiofaciale : anticorps et cancer

A

LGI1 : thymome (10%)

surface

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13
Q

anti mGlu receptor 1 : syndrome et cancer

A

ataxie
lymphome de hodgkin

surface

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14
Q

anti mGLu récepteur 5 : syndrome et cancer

A

syndrome ophelia (encephalite limbique)

lymphome de hodgkin

surface

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15
Q

anti NMDA : syndrome et cancer

A

psychose, convulsion, encephalopathi, dyskinésie orofaciale, hypoventilation

teratome ovarien

surface

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16
Q

anti PCA-Tr/DNER

A

cerebellar ataxia, brainstem encephalitis

lymphome de hodgkin

surface

17
Q

anti P/Q N-type voltage-gated calcium (syndrome et cancer)

A

lambert eaton, ataxie, SCLC

surface

18
Q

AGNA/SOX1 : syndrome et cancer

A

lamber eaton
sclc
intracellulaire

19
Q

2 anticorps du lambert eaton

A

P/Q type and N-type voltage gated calcium channels et agna/sox1

20
Q

antiamphiphysin syndrome et cancer

A

stiff person syndrome

cancer du sein
sclc

antigène intracellulaire

21
Q

anti Hu (anna-1) syndrome et cancer

A

neuronopathie sensitive, encephalite limbique, dysmotilité intestinale, ospsoclonus-myoclonus

neuroblastome, thymome, sclc

22
Q

anti-R1 (anna-2) syndrome et cancer

A

ospsoclonus-myoclonus (Adulte) dystonie de la machoire, laryngospasme, encephalite du tronc, ataxie

SCLC, cancer du sein

intracellulaire

23
Q

Anti CRMP-5/anti-cv2 SYNDROMES ET CANCER

A

Chorée, rétinopathie, myelopathie, neuropathie, encephalite

SCLC, thymome

24
Q

anti gad65 syndrome et cancer

A

stiff person syndrome
encephalite limbique
ataxie

SCLC

intracellulaire

25
GFAP
méningoencephalitomyélite, oedeme disque otpique. peut coexsiter avec anti-NMDA et anti-AQ4 teratome intracellulaire
26
AntiGRAF1
rhombencephalite cancer de l'ovaire intracelullaire
27
anti ITPR1 syndrome et cancer
anomalie MEO, ataxie cancer du sein, cancer du poumon, néo hématologique intracellulaire
28
Kelch-like protiein 11
ataxie, rhombencephalite, incluant perte d'audition et vertige seminome intracellulaire
29
Anti Ma1, Ma2
encephalite limbique, narcolepsy/cataplexy, rhombencephalite cancer testiculaire (Ma2) ou tumeurs diverses itnracellulaire
30
anti neurochondrin
ataxie cancer utérin intracellulaire
31
neuronal intermediate filament light
encephalopathy, ataxie, myelopathie cancer neuroendocrinien (SCLC, carcinome cellule de meckel intracellulaire
32
anti PDE10A
encephalopathy chorée post-immune checkpoint-inhibitors cancer du poumons, rein, pancreas intracellulaire
33
PCA-1/CDR2
ataxie cancer ovaire, endomètre, trompe de fallope, sein intracellulaire
34
pca-2 (map1b
manifestation clinique diverse SCLC intracellulaire
35
protéine kinase C
ataxie cancer du poumon non petites cellules, ADNK hepatobilliaire intracellulaire
36
anti recoverin
retinopathi SCLC intracellulaire
37
anti TRIM46
encephalite, ataxie sclc intracellulaire
38
zic4
Ataxie sclc intracellulaire