Syphilis Flashcards
characterized by the appearance of a painless sore called a chancre.
Primary Syphilis
transmission of the spirochete Treponema pallidum from the mother to the fetus, resulting in premature birth.
Conginetal Syphilis
involves a rash, fever, sore throat, and other symptoms.
Secondary Syphilis
most severe stage, causing damage to organs such as the heart, brain, and nerves.
Tertiary Syphilis
divided into early (within a year of infection) and late (more than a year after infection) stages, with no symptoms present.
Latent
an infection involving the central nervous system (CNS) and, can occur at any time after infection.
Neurosyphilis
Causative agent of Syphilis
Treponema pallidum
Family of T. pallidum
Spirochaetaceae
Mode of transmission for Syphilis:
- Direct contact (sexual contact)
- Across the placenta
- Body fluids
Initial lesion is a painless, nonbleeding ulcer
Chancre
includes skin rashes, low-grade fever, malaise, weight loss, arthralgia, and lymphadenopathy.
Secondary Syphilis
formed by coalescence or large, pale, flat – topped papules. Occurs in warm, moist areas such as the perianal area and are highly infectious. Trademark of secondary syphilis.
Condyloma lata
existing but not yet developed
Latent Phase
Can cause blindness and sensitivity
Neurosyphilis
most common complication of late syphilis. May be single or multiple, They are ordinarily indolent, slowly progressive, and indurated granulomata, with central healing and atrophic scar surrounded by hyperpigmented borders.
Gummas
syphilis lesion due to hypersensitivity reaction to treponemal antigens
Gummas