Systemic Diseases and the Mouth

Question 1

Suspected cause of Giant cell lesions

Answer 1

Excess PTH of osteoclasts

Question 2

Addisons disease presentation in oral mucosa

Answer 2

Increased ACTH
Mucosal pigmentation

Question 3

OFG Phenotype

Answer 3

Ginger + freckles

Question 4

List clinical features of OFG

Answer 4

Facial/oral/lip swelling
Linear oral ulceration
Angular cheilitis
Tongue fissuring
Full thickness gingival swelling
Cobblestone buccal mucosa

Question 5

Angio-oedema vs OFG

Answer 5

Angio-oedema
- Swelling comes up quickly
- Settles quickly 24-48hrs

OFG
- Continuous swelling
- Settles slowly

Question 6

Describe OFG in a pt friendly manner

Answer 6

Uncommon condition that causes persistent swellings in lip/face/mouth
The cause is unknown but may be an immunological/allergy to foods
Investigations are required as presentation can be similar to crohs disease

Question 7

Symptoms of OFG

Answer 7

Lip/face swelling
Dry red skin
Painful bleeding gums
Ulcers (may lost a month)
Pain worse with spicy/hard foods

Question 8

What is Crohn’s disease

Answer 8

Inflammatory bowel disease
Inflammation in digestive tract
- Abdominal pain
- Severe diarrhoea
- Fatigue
- Weight loss/malnutrition