Systems Exam 4 Pharm Flashcards

1
Q

What do Diuretics treat?

A

HTN & CHF

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2
Q

Diuretics effect & adverse effects

A

Effect- on water balance and electrolyte balance by controlling pressure and amt of fluid in CV system

Adverse- electrolyte imbalance, orthostatic hypotension, weakness, fatigue, confusion, mood swings

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3
Q

What do Beta Blockers treat?

A

HTN, CHF, Arrhythmia, MI recovery, angina

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4
Q

How do beta blockers work?

A

bind to the heart (BETA1) and block the effects of catecholamines (epi & nor)

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5
Q

Beta Blockers Suffix

A

-olol

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6
Q

Beta Blockers Effect

A

decrease HR and blunt with exercise; decrease force of contraction

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7
Q

Beta Blockers Adverse Effect

A

decrease max exercise capacity
decrease max HR by 20-30
orthostatic hypotension

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8
Q

Calcium Channel Blockers Effect

A
  • limit calcium entry into vascular smooth muscle (& heart muscle)
  • vasodilator
  • controls/stabilizes heart
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9
Q

What do Calcium Channel Blockers treat

A

HTN, Angina, Arrhythmias

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10
Q

Calcium Channel Blockers Adverse Effect

A

-feet swelling
-orthostatic hypotension
- altered HR (can create a diff arrhythmia)

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11
Q

Important thing to avoid with VASODILATORS

A

HEAT bc it leads to profound hypotension and increased BP

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12
Q

Vasodilators Action

A
  • act on smooth muscle by inhibiting contraction
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13
Q

Vasodilators treat
Vasodilators adverse effect

A
  • high bp & heart failure
  • orthostatic hypotension
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14
Q

Digitals treat

A

CHF

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15
Q

Digitals Margin of Error

A

very small margin of error so a small increase can be FATAL

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16
Q

Digitals Adverse Effects

A

Digital Toxicity: fatigue, GI distress, depression, blurry vision, confusion, arrhythmias

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17
Q

Digitals Action

A
  • increase myocardial contraction
  • increase CO
18
Q

ACE Inhibitors

A

Cannot produce ANG II

19
Q

ACE Inhibitors Treat

A

HTN and Heart Failure

20
Q

ACE Inhibitor suffix

A

-pril

21
Q

ACE Inhibitor Adverse effect

A

dry unproductive cough

22
Q

Angiotensin II Action

A
  • Vasoconstriction
  • Thickens blood vessels which chokes blood flow
23
Q

Asprin Action

A

reduces blood clots
- inhibits platelet function and prevents arterial thrombo.

24
Q

Biggest risk for asprin and anticoagulants

A

hemorrhage

25
Q

Anticoagulants Action

A

prevent DVT
for overactive clotting

26
Q

Anticoagulant Heparin Speed

A

works rapidly

27
Q

Oral Anticoagulant (warfarin & coumadin)
- Speed
- Action
- Concern

A
  • Takes 3-4 days
  • inhibits vitamin K
  • be careful with leafy greens
28
Q

Statins (liptor, zocor, crestor) Treat
Adverse Effects

A
  • hyperlipidemia
  • Myopathy & neuromuscular probs
29
Q

Alpha 1 Agonist function

A

Vasoconstriction
(Sympathetic)

30
Q

Alpha 2 agonist

A

Vasodilator & decrease HR
(Parasympathetic)

31
Q

Beta 1 Agonist

A

Increase HR & contractility
(Sympathetic)

32
Q

Beta 2 agonist

A

Acts on lungs
(Sympathetic)

33
Q

Borderline LDL

A

130-159

34
Q

Desirable cholesterol

A

<200

35
Q

Borderline cholesterol

A

<200-239

36
Q

High cholesterol

A

> 240

37
Q

Desirable LDL

A

<130

38
Q

Anticholinergic agents effect on hr

A

Increase resting hr

Suppress parasympathetic

39
Q

What treats angina pectoris

A

Organic nitrates
Beta blockers
Calcium channel blockers

40
Q

Vascular smooth muscle dilation caused by what

A

Organic nitrates