Sz and Related Disorders Flashcards

(31 cards)

1
Q

What are the two most common types of hallucinations in schizophrenia?

A

Auditory hallucinations – Hearing voices or sounds.

Visual hallucinations – Seeing things that aren’t there.

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2
Q

What is the prevalence of schizophrenia in the general population vs. children of two affected parents?

A

General population: ~1%

With two schizophrenic parents: ~46% risk

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3
Q

What are the “Four A’s” of schizophrenia according to Eugen Bleuler?

A

Affect – Blunted or inappropriate emotions

Association – Disordered thinking and speech

Ambivalence – Conflicting feelings or thoughts

Autism – Social withdrawal and inward focus

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4
Q

Is “split brain” a better description of DID or schizophrenia? Why?

A

It’s more accurate for Dissociative Identity Disorder (DID) because DID involves a split in identity or personality, while schizophrenia involves a split in thinking, emotion, and perception, not identity.

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5
Q

How did Kraepelin define dementia praecox, and how did his view differ from Bleuler’s?

A

Kraepelin: Defined dementia praecox as a progressive, irreversible disorder with early onset and decline.

Bleuler: Renamed it schizophrenia and believed it had a more variable course, not always leading to deterioration .

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6
Q

What environmental circumstances, both in childhood and in later life, hypothesized to be risk
factors for schizophrenia?

A

Childhood: Prenatal exposure to infection, complications during pregnancy or delivery, and early brain injury.

Later life: Stressful life events, high family expressed emotion, cannabis use in adolescence.

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7
Q

What are thought echoing, insertion, and withdrawal?

A

Thought echoing: Hearing one’s own thoughts spoken aloud.

Thought insertion: Belief that thoughts are being placed into one’s mind by an external source.

Thought withdrawal: Belief that thoughts are being removed from one’s mind by someone or something else.

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8
Q

What was Kurt Schneider’s objection to Bleuler’s “Four A’s,” and what did he propose instead?

A

Schneider thought Bleuler’s Four A’s were too broad and hard to diagnose. He proposed focusing on First-Rank Symptoms—specific psychotic features strongly suggestive of schizophrenia.

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9
Q

What are Schneider’s First-Rank and Second-Rank Symptoms?

A

First-Rank: Include thought insertion, withdrawal, broadcasting; auditory hallucinations (e.g., voices commenting); and delusions of control.

Second-Rank: Include other symptoms like mood changes, social withdrawal, and less specific disturbances.

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10
Q

Are people with treated schizophrenia usually dangerous to others or themselves?

A

To others: Rarely. Most treated individuals are not violent and are more likely to be victims.

To themselves: Yes—higher suicide risk, especially early in treatment or after relapse.

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11
Q

How can delusions interfere with treating schizophrenia?

A

Delusions can cause mistrust of doctors, refusal to take medication, and poor insight into illness, all of which make treatment harder.

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12
Q

What are the typical phases in the progression of schizophrenia?

A

Prodromal Phase – Subtle symptoms (withdrawal, odd thoughts) begin.

Active Phase – Full symptoms appear (delusions, hallucinations, disorganized speech).

Residual Phase – Major symptoms fade, but some impairment remains.

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13
Q

What are the main thought and speech disturbances in schizophrenia?

A

Loose associations: Ideas shift with little connection.

Neologisms: Made-up words with personal meaning.

Clang associations: Speech driven by rhyme, not meaning.

Perseveration: Repeating words or ideas.

Blocking: Sudden interruption of thought or speech.

Word salad: Jumbled, incoherent speech.

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14
Q

What are cognitive and emotional abnormalities in schizophrenia?

A

Cognitive: Poor attention, memory issues, impaired executive function (planning, problem-solving).

Emotional: Flat or inappropriate affect, trouble recognizing others’ emotions, poor emotional regulation.

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15
Q

What’s the difference between positive and negative symptoms of schizophrenia?

A

Positive symptoms: Excesses or distortions (e.g., delusions, hallucinations, disorganized speech).

Negative symptoms: Losses or deficits (e.g., flat affect, lack of motivation, social withdrawal).

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16
Q

What subtypes of schizophrenia were in earlier DSM versions but removed in DSM-5?

A

Paranoid: Dominated by delusions or hallucinations.

Disorganized: Disorganized speech, behavior, flat/inappropriate affect.

Catatonic: Motor immobility or excessive movement.

Undifferentiated: Mixed symptoms that don’t fit one subtype.

Residual: Fewer active symptoms, but still impaired.

17
Q

What is Crow’s distinction between Type I and Type II schizophrenia?

A

Type I: Dominated by positive symptoms (e.g., delusions, hallucinations); better treatment response; may involve excess dopamine.

Type II: Dominated by negative symptoms (e.g., flat affect, withdrawal); poorer prognosis; linked to brain structural abnormalities

18
Q

What does “lack of ego boundaries” mean in schizophrenia?

A

It refers to difficulty distinguishing the self from others or the external world—leading to confusion between inner thoughts and external reality.

19
Q

What are the main DSM-5 diagnostic criteria for schizophrenia?

A

Two or more symptoms for 1 month, with signs lasting at least 6 months:

Delusions

Hallucinations

Disorganized speech

Disorganized or catatonic behavior

Negative symptoms (e.g., flat affect)

20
Q

What’s the difference between schizophrenia and schizophreniform disorder?

A

Schizophrenia: Symptoms last at least 6 months.

Schizophreniform disorder: Same symptoms, but last more than 1 month and less than 6 months .

21
Q

How do we distinguish between schizophrenia and schizoaffective disorder? Why is it hard?

A

Schizophrenia: Mood symptoms are brief or secondary.

Schizoaffective disorder: Mood symptoms (depression or mania) are present for a substantial part of the illness, with at least 2 weeks of psychosis alone.

Hard to distinguish: Because mood and psychotic symptoms often overlap or fluctuate

22
Q

A man in his 40s suddenly shows psychotic symptoms with no prior history or substance use. Is it likely schizophrenia? If not, what is more likely?

A

Unlikely schizophrenia—it usually starts earlier and builds gradually. A brief psychotic disorder or medical condition is more likely, given the sudden onset in midlife with no prior history

23
Q

What is the relationship between schizotypal personality disorder and schizophrenia?

A

Schizotypal personality disorder shares features with schizophrenia (odd thinking, paranoia, social anxiety), but symptoms are less severe and do not include full psychosis. It’s considered part of the schizophrenia spectrum

24
Q

What is primary narcissism, and how does Harry Stack Sullivan’s psychodynamic theory explain schizophrenia?

A

Primary narcissism: A regression to an early stage where the self is the focus, common in psychodynamic views of schizophrenia.

Sullivan’s view: Schizophrenia arises from interpersonal failures and withdrawal due to early mistrust and anxiety, leading to distorted self-perception and social disconnection

25
What did Ullman & Krasner and Haughton & Ayllon contribute to understanding schizophrenia? What are the limits of their views?
Ullman & Krasner: Argued schizophrenia behaviors may be reinforced by attention. Haughton & Ayllon: Showed that hospital environments may unintentionally reinforce bizarre behavior. Limitations: These don’t explain the cause of schizophrenia—only how symptoms might persist or worsen due to environment .
26
What is the evidence for a genetic contribution to schizophrenia?
Higher risk in relatives: 1% in general population vs. ~46% for children of two affected parents. Twin studies: Concordance is ~48% in identical twins, much higher than in fraternal twins or siblings. Adoption studies: Show higher rates in biological vs. adoptive relatives of people with schizophrenia
27
What neurotransmitter abnormalities are linked to schizophrenia?
Dopamine: Overactivity in certain brain areas (dopamine hypothesis). Glutamate: Possible underactivity, especially in prefrontal cortex. Serotonin: May interact with dopamine, influencing symptoms
28
How does the COMT gene affect schizophrenia onset, and under what conditions?
The COMT gene helps regulate dopamine in the prefrontal cortex. A certain variant may increase schizophrenia risk, especially if combined with early cannabis use during adolescence, which can disrupt brain development
29
What are “schizophrenogenic mothers” and how might they increase schizophrenia risk?
A schizophrenogenic mother is a cold, domineering, and emotionally distant parent, theorized to confuse and emotionally damage the child—possibly contributing to schizophrenia. Note: This is an outdated theory with little scientific support and is largely rejected today
30
What roles do expressed emotion and double-bind communication play in schizophrenia?
Expressed Emotion (EE): High levels of criticism, hostility, or overinvolvement by family members can raise the risk of relapse. Double-bind communication: Receiving conflicting emotional messages (e.g., love and rejection) may contribute to thought confusion and psychotic symptoms. Note: Double-bind theory is mostly unsupported, but EE is a well-established risk factor .
31
Why is family support important in treating schizophrenia?
Supportive families help reduce stress and relapse risk. Family education and therapy can improve communication, reduce expressed emotion, and support medication adherence, all of which improve outcomes .