T Flashcards

(56 cards)

1
Q

Thyroid hormone stimulates

A

Fat metabolism

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2
Q

Hyperthyroidism one might see

A

Loss of muscle mass, Hi anxiety, exophthalmos, A high metabolic rate

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3
Q

Goitrogenic substances found in cabbage,
An autoimmune attack on the thyroid gland,
Inadequate iodine in diet
A genetic defect TRH receptors

All of the following above cause what?

A

Hypothyroidism

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4
Q

Thyroid Hormones mechanism of action is similar to

A

Steroids

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5
Q

Thyroid hormones help the body cope with a cold environment by

A

Stimulating ATP production, appetite, the number and size of mitochondria

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6
Q

The ability of the thyroid gland to respond temperature of the environment is dependent on

A

Of the hypothalamus to detect changes in body temperature

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7
Q

Myxedema is a sign of

A

Hyperthyroidism

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8
Q

Hormones which act inside a cell must be

A

Lipid soluble

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9
Q

Thyroxin

A

Is the major form of thyroid hormone which regulates the blood

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10
Q

To make thyroid hormones the thyroid follicle cell must

A

Be able to trap iodine
Oxidize iodine
Make thyroglobulin
Cleave t3 and t4

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11
Q

Hormones act on which cells

A

Only the cells that have receptors for them

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12
Q

Steroid hormones and thyroid hormones

A

Have similar mechanism of action,
Act inside cell
Influence gene transcription

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13
Q

Pro opiomelanocortin is produced by the

A

Anterior pituitary as a precursor for ACTH , endorphins, and MSH

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14
Q

Which of the following elevates mood and decreases sensitivity to pain

A

Endorphins

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15
Q

individuals with high levels of cortisol receptors above the waist and High levels of insulin receptors below the waist is likely to have a body shape that resembles

A

A pear (gynoid)

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16
Q

Which of the following is not a symptom of cushings disease

A

Low blood pressure

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17
Q

A pheochromocytoma that produces epinephrine, dopamine, and norepinephrine will cause

A

Heart palpitations, high anxiety, abdominal pain, and nausea

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18
Q

Alpha and beta adrenergic receptors differ from each other in that

A

Alpha and beta receptors activate different 2nd messenger systems

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19
Q

Epinephrine stimulates

A

The rate of blood coagulation

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20
Q

Which of the following is a response mediated by Alpha adrenergic receptor’s

A

Vasoconstriction

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21
Q

Alpha and beta adrenergic receptors

A

Often mediate opposite responses,
can be blocked by different compounds,
can be found on the same cells in different propositions

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22
Q

When Norepinephrine acts as a hormone

A

It has more enzymes acting to destroy it then it has as a neurotransmitter

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23
Q

Insulin and GH synergize in their actions on

A

Metabolism of protein,
DNA,
CHO,
fat

24
Q

Pancreatic somatostatin suppresses

A

Insulin secretion

25
Glucagon stimulates
Insulin secretion
26
Which of the following does not stimulate glucagon secretion
High blood glucose
27
Which of the following stimulates insulin secretion
Digestive tract hormones, the Vegas nerve in response to thoughts of food, AA
28
Symptoms of high blood glucose , acidosis, rapid weight loss and irrational behavior are most typical of
Diabetes type one insulin dependent
29
Diabetes type 2
Is due to a post receptor defect is response to insulin
30
In the pre diabetic state, a person with diabetes type 2 is likely to experience
a tendency to gain weight easily
31
Insulin does what?
Lowers blood glucose levels
32
When rising thyroid hormones act in negative feedback on TSH secretion
Act on the anterior pituitary
33
``` Hyperthyroidism Hypothyroidism Pan hypo pituitary conditions Excess prolactin All of the above will cause problems with what? ```
Reproductive problems
34
The hypothalamus synthesizes
CRH
35
A child born without a functioning thyroid gland
Needs to be supplemented with thyroid hormone to avoid severe growth and mental retardation
36
Thyroid hormones enter what and do what?
Enter cell and regulate gene expression
37
The rate limiting step in cortisol production is
Cholesterol side chain cleavage
38
Which of the following are 21 carbon steroids
Progestins
39
Which of the following is the precursor for all of the others
Cholesterol
40
The zona glomerulosa produces
Aldosterone
41
Aldosterone secretion is directly stimulated by angiotensin 2
Angiotensin 2
42
Rennin is secreted in response to
Sympathetic stimulation of the kidney
43
Aldosterone stimulates
K+ secretion in urine
44
Atrial Naturetic hormone stimulates what?
The secretion of Na+ in urine
45
Corticotrophin is produced by the
Anterior pituitary
46
Atrial natriuretic hormone is produced by the
Heart
47
If the liver is diseased and unable to metabolize aldosterone
Elevated blood levels of aldosterone will contribute to hypertension
48
Renin production is stimulated by
Low blood pressure sensed by juxtaglomerular cells
49
In the total absence of Cortisol and aldosterone
Severe loss of blood volume will lead to circulatory shock
50
On a boring day the highest levels of cortisol will be observed when?
7-8 am before breakfast
51
Pain or injury, emotional stress, cytokines produced by the immune system Will stimulate what?
Cortisol secretion
52
Excessively high levels of cortisol
Suppress the activity of the immune system
53
Cortisol exerts negative feedback action on the
Limbic system Hypothalamus Anterior pituitary
54
Theca interna cells secrete
Androgens
55
Insulin stimulates
Lipogenesis
56
Which of the following can bind to aldosterone receptors
Cortisol aldosterone progesterone