T1DM Flashcards
(16 cards)
What antibodies do we screen for in potential T1DM patients?
-GAD: glutamic acid decarboxylase
-IA-2: islet antigen 2
-ZnT8: zinc transporter 8
What is Teplizumab?
-treatment used to delay onset of symtomatic T1DM
-age ≥ 8 years with stage 2 T1DM
When should T1DM patients be screened for autoimmune thyroid disease?
-upon diagnosis and thereafter at repeated intervals
How do we calculate the insulin sensitivity factor (correction factor)?
(1800/TDD)
How do we calculate the insulin to carb ratio?
(500/TDD)
How does AID calculate bolus dose to give?
I:C + correction dose using
How do we calculate TDD?
0.5 x weight (kg) = TDD
_____ (micro/macrovascular) complications are more common in T1DM, while _______ (micro/macrovascular) complications are more common in T2DM.
T1DM: microvascular
T2DM: macovascular
What are the four pillars to reduction in diabetes complications?
- glycemic management
- BP management
- Lipid management
- Agents with CV and kidney benefit
What type of patient population did DCCT include? (T1DM or T2DM)?
-T1DM
What were the key findings from DCCT?
-intensive diabetes therapy significantly reduced microvascular complications in patients with T1DM
What type of patient population did EDIC include?
T1DM
What were the key findings from EDIC?
-early and intensive BG control = decreased CV diseases, eye disease, kidney disease, nerve problems
When should adults with T1DM have an eye exam?
within 5 years after onset of diabetes
How often should adults with T1DM have eye screening for retinopathy?
every 1-2 years
