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Mental Health > Table 14.6 FDA-Approved Drugs for Major Depressive Disorder > Flashcards

Table 14.6 FDA-Approved Drugs for Major Depressive Disorder Flashcards

1
Q

SSRI
drugs

A

citalopram
escitalopram
fluoxetine
paroxetine
sertraline

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2
Q

SSRI
action

A

block the synaptic reuptake of serotonin

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3
Q

SSRI
notes

A

first line of treatment
either activate or sedate
risk of overdose is not lethal

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4
Q

SSRI
side effects

A

agitation, insomnia, headache, N/V, sexual dysfunction, hyponatremia

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5
Q

SSRI
warning

A

discontinuation syndrome
- dizziness
- insomnia
- nervousness
- irritability
- nausea

make sure to taper when coming off of drugs

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6
Q

SNRI
drugs

A

desvenlafaxine
duloxetine
levomilnacipran
venlafaxine

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7
Q

SNRI
action

A

blocks synaptic reuptake of serotonin and norepinephrine

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8
Q

What is a popular SNRI that is tried after SSRI

A

Effexor/venlafaxine

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9
Q

SNRI
side effects

A

nausea, dry mouth, insomnia, constipation,

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10
Q

TCA
drugs

A

amitriptyline
amoxapine
desipramine
doxepin
imipramine
maprotiline
nortriptlyine
protriptyline
trimipramine

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11
Q

TCA
action

A

inhibit synaptic reuptake of serotonin and norepinephrine. Antagonize adrenergic, histamine, muscarinic receptors

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12
Q

TCA
notes

A

therapeutic effects similar to SSRI, side effects more prominent

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13
Q

TCA
side effects

A

dry mouth, constipation, urinary retention, blurred vision, hypotension, cardiac toxicity, sedation

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14
Q

TCA
warnings

A

lethal in overdose

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15
Q

MAOI
drugs

A

isocarboxazid
phenelzine
selegiline
tranylcypromine

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16
Q

MAOI
action

A

inhibits the enzyme monamine oxidase, which normally breaks down neurotransmitters

17
Q

MAOI
notes

A

strict dietary restrictions and potential drug interactions

18
Q

MAOI
side effects

A

insomnia
nausea
agitation
confusion
hypertensive crisis

19
Q

MAOI
warnings

A

cotraintidated in SSRI
hypertensive crisis

Mental Health (82 decks)

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