Tandmely repeated DNA

Question 1

What is tandemly repeated DNA?

Answer 1

A sequence that is repeated many times (>3) HEAD TO TAIL along the DNA in an array

Question 2

What are the unit repeats of tandemly DNA like?

Answer 2

• Unit repeats are similar but not necessarily identical
• Unit repeats may vary in length between 2bp & >10kb

Question 3

What are the 2 key features of tandmely repeated DNA?

Answer 3

1 - Tandmely repeated seq are almost always POLYMORPHIC in copy number

2 - The tandmely repeated seq within an array are similar but not always identical in seq

Question 4

What does it mean for tandemly repeated sequence to be polymorphic in copy number?

Answer 4

Polymorphic –> means that there are many different forms they can come in

e.g. they can have repeats of 4, 7,8 or even 9/10