Targets Flashcards
(8 cards)
1
Q
glucocorticoids
- site of action
- function
A
- glucocorticoid response elements in DNA
- regulate gene txn
2
Q
Muromonab-CD3
- site of action
- function
A
- TCR complex
- blocks antigen recognition
3
Q
cyclosporine
- site of action
- function
A
- Calcinuerine
- inhibits phosphatase activity
4
Q
tacroliumus
- site of action
- function
A
- calcineurine
- inhibits phosphatase activity
5
Q
azathioprine
- site of action
- function
A
- deoxyribonucleic acid dehydrogenase
- inhibits activity
6
Q
mycophenolate
- site of action
- function
A
- inosine monophosphate dehydrogenase
- inhibits activity
7
Q
dalizumab, basiliximab
- site of action
- function
A
- IL-2 receptor
- block IL-2 mediated activation
8
Q
sirollimus
- site of action
- function
A
- protein kinase involved in cell-cycle progression (mTOR)
- inhibits activity
