Tema 11 Glucólisis Flashcards
(35 cards)
What is the first step of glycolysis?
The conversion of glucose to glucose-6-phosphate.
True or False: Glycolysis occurs in the mitochondria.
False, glycolysis occurs in the cytoplasm.
What enzyme catalyzes the conversion of glucose to glucose-6-phosphate?
Hexokinase.
Fill in the blank: The second step of glycolysis converts glucose-6-phosphate to ______.
fructose-6-phosphate.
What is the third step of glycolysis?
The conversion of fructose-6-phosphate to fructose-1,6-bisphosphate.
Which enzyme is responsible for the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate?
Phosphofructokinase.
What are the two products of the cleavage of fructose-1,6-bisphosphate?
Dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (G3P).
True or False: Glycolysis produces ATP.
True.
What is the net gain of ATP in glycolysis?
2 ATP molecules.
What is produced in the final step of glycolysis?
Pyruvate.
Which enzyme catalyzes the conversion of phosphoenolpyruvate to pyruvate?
Pyruvate kinase.
Fill in the blank: Glycolysis is an ______ pathway.
anaerobic.
What is the role of NAD+ in glycolysis?
It acts as an electron carrier, being reduced to NADH.
How many molecules of NADH are produced per glucose molecule in glycolysis?
2 molecules of NADH.
What is the fate of pyruvate in the presence of oxygen?
It is converted to acetyl-CoA for entry into the Krebs cycle.
What is the fate of pyruvate in the absence of oxygen?
It undergoes fermentation to produce lactate or ethanol.
Which step of glycolysis is considered the ‘committed step’?
The conversion of fructose-6-phosphate to fructose-1,6-bisphosphate.
What is the overall reaction of glycolysis?
1 glucose + 2 NAD+ + 2 ADP + 2 Pi → 2 pyruvate + 2 NADH + 2 ATP.
True or False: Glycolysis is an energy-investment phase followed by an energy-payoff phase.
True.
What is the role of ATP in the energy-investment phase of glycolysis?
ATP is used to phosphorylate glucose and fructose-6-phosphate.
How many total reactions are there in glycolysis?
Ten reactions.
Which reaction in glycolysis involves the isomerization of DHAP to G3P?
The fifth reaction.
Fill in the blank: The conversion of G3P to 1,3-bisphosphoglycerate is coupled with the reduction of ______.
NAD+.
What type of reaction is the conversion of phosphoenolpyruvate to pyruvate?
A substrate-level phosphorylation reaction.
