Term 4-1

Question 1

L-1

Focused open ended skills consists of which of the following?

Reflection
Non-verbal communication
Silence
Continuers

Answer 1

Reflection

Question 2

L-1

Non focused, open ended skills consists of which of the following?

Reflection
Echoing
Summarization
Silence

Answer 2

Silence

Question 3

L-1

In terms of emotion seeking skills, what does the mnemonic FIFE stand for?

Answer 3

Feelings toward the problem
Idea of belief of the cause of the problem
Function or impact of the problem on personal life
Expectation of the disease

Question 4

L-1

In terms empathy skills, what does the mnemonic NURS stand for?

Answer 4

Name
Understand
Respect
Support

Question 5

L-2

Mr Smith smoked 1 pack of cigarettes a day for 5 years. What is his number of pack-years?

5
10
15
20

Answer 5

5

Question 6

L-2

What are the five P’s for sexual history?

Answer 6

Partners
Practices
Protection STD's
Past history of STD's
Prevention of pregnancy

Question 7

L-3

What is hydropic change?

Cell death
Fatty change
Cellular swelling
Cell replication

Answer 7

Cellular swelling

Question 8

L-3

What is the morphology of irreversible cell injury?

Dilation of the ER
Bleb formation
Small clear vacuoles within the cytoplasm
Vacuolization of mitochondria

Answer 8

Vacuolization of mitochondria

Question 9

L-4

Give an example of physiological hypertrophy

Increase in Cardiac muscle during hypertension
Increase in glandular epithelium of breasts during puberty
Enlargement of thyroid
Increase in size of uterus during pregnancy

Answer 9

Increase in size of uterus during pregnancy

Question 10

L-4

Give an example of physiological hyperplasia

Increase in Cardiac muscle during hypertension
Increase in glandular epithelium of breasts during puberty
Enlargement of thyroid
Increase in size of uterus during pregnancy

Answer 10

Increase in glandular epithelium of breasts during puberty

Question 11

L-4

Give an example of pathologic hyperplasia

Increase in Cardiac muscle during hypertension
Increase in glandular epithelium of breasts during puberty
Enlargement of thyroid
Increase in size of uterus during pregnancy

Answer 11

Enlargement of thyroid

Question 12

L-4

What are the cardinal signs of inflammation

Answer 12

Heat-calor
Redness-rubor
Swelling-tumor
Pain-dolor
Loss of function-function laesa

Question 13

L-5

Vinca alkaloids arrest the cell in what phase?

Prophase
Anaphase
Metaphase
Telephase

Answer 13

Metaphase

Question 14

L-5

Statins are an example of what type of drug target

Ion channel
Enzymes
Transporters
Structural Proteins

Answer 14

Enzymes

Question 15

L-5

Lidocaine targets what

Voltage gated sodium channels
G protein linked receptors
Cytokine receptors
Nuclear receptors

Answer 15

Voltage gated sodium channels

Question 16

L-6

Marked by exudation of cell poor fluid into spaces created by cell injury or into body cavities describes what type of inflammation

Serous
Fibrinous
Suppurative
Ulcers

Answer 16

Serous

Question 17

L-6

Which is responsible for opsonization

IgA
IgM
IgG
C5a

Answer 17

IgG

Question 18

L-7

Which is a non-competitive antagonist

Protamine
Heparin
Aspirin
Ketamin

Answer 18

Ketamin

Question 19

L-7

Which is a competitive irreversible antagonist

Protamine
Heparin
Aspirin
Ketamin

Answer 19

Aspirin

Question 20

L-9

Classically activated macrophages are induced by which cytokine

IFN gamma
IL-13
IL-4
ROS

Answer 20

IFN gamma

Question 21

L-9

Which diseases are characterized by granulomatous inflammation

Tuberculosis
leprosy
Syphilis
All of the above

Answer 21

All of the above

Question 22

L-9

What is the WBC count for a leukemoid reaction

10000-14000 cells/mL
1000-4000
4001-10000
40000-100000

Answer 22

40000-100000

Question 23

L-11

Which method of drug administration produces 100% bioavailability

oral
IV
sublingual
anal

Answer 23

IV

Question 24

L-11

For a weak acid which form is more liposoluble

protonated
unprotonated

Answer 24

protonated

Question 25

L-11 Weak acids are excreted faster in alkaline urine acidic urine

Answer 25

alkaline

Question 26

L-13 What is the drug given for the treatment of an overdose of acetaminophen? Digoxin N-acetylcysteine Erythromycin Rifampin

Answer 26

N-acetylcysteine

Question 27

L-13 Which drug does not increase the transcription of cytochrome P450? phenobarbitol aspirin rifampin carbamazepine

Answer 27

aspirin

Question 28

L-12 What is an example of labile tissue smooth muscle cardiac muscle epidermis neurons

Answer 28

epidermis

Question 29

L-12 Names the 4 steps to scar formation.

Answer 29

Maintenance of hemostasis Inflammation Cellular proliferation Tissue remodeling

Question 30

L-14 What are the three main characteristics of an organ affected by amyloidosis?

Answer 30

enlargement firm waxy

Question 31

L-14 What are the 5 main types of amyloids?

Answer 31

``` B-2 amyloid alzheimer's B-2 microglobulin dialysis AL-lambda light chain B cells AA-liver, chronic inflammatory diseases Transthyretin familia neuropath ```

Question 32

L-15 What three drugs display zero order elimination?

Answer 32

aspirin ethanol phenytoin

Question 33

L-15 How many half-lives does it take to attain steady state?

Answer 33

4

Question 34

L-16 Lipofucsin is Intracellular/exogenous/inert Intracellular/endogenous/inert Extracellular/exogenous/active Extracellular/exogenous/active

Answer 34

Intracellular/endogenous/inert

Question 35

L-16 Dystrophic calcification includes cell injury/death normal serum Ca++ levels occurs in coronary artery and breasts all of the above

Answer 35

all of the above

Question 36

L-18 What are the characteristics of dysplasia

Answer 36

cellular pleomorphism nuclear pleomorphism disordered arrangement of cells

Question 37

L-18 Give three characteristics of benign tumors

Answer 37

well differentiated slow growth does not invade surrounding normal tissue

Question 38

L-19 N-acetyltransferase 2 catalyzes the acetylation of which drug succinylcholine metoprolol isoniazid codeine

Answer 38

isoniazid

Question 39

L-19 Butyrylcholinesterase interacts with which drug succinylcholine metoprolol isoniazid codeine

Answer 39

succinylcholine

Question 40

L-20 What are the 3 phases of metastasis

Answer 40

invasion of extracellular matrix movement thru the interstitial tissue vascular dissemination and homing of tumor cells

Question 41

L-20 What enzyme breaks down the extracellular matrix

Answer 41

collagenase

Question 42

L-21 What is the proper chemotherapy for neoplasms that are not amenable to surgery primary adjuvant neoadjuvant

Answer 42

primary

Question 43

L-21 Which drug rescues bone marrow from the effects of methotrexate Mesna Amifostine Leucovorin Amifostime

Answer 43

Leucovorin

Question 44

L-22 What is a factor of cancer cachexia? reduced food intake reduced synthesis and storage of fat TNF alpha all of the above

Answer 44

all of the above

Question 45

L-22 What causes fever? IL-1 IL-2 IL-4 IL-5

Answer 45

IL-1

Question 46

L-22 Which immunohistochemical stain is used for epithelium? desmin keratin vimentin PSA

Answer 46

keratin

Question 47

L-23 Which drug reduces the cardiotoxicity caused by anthracyclines dexrazoxane leucovorin allopurinol 5-HT

Answer 47

dexrazone

Question 48

L-23 Which drug potentiates the activity of 5-fluorouracil dexrazoxane leucovorin allopurinol 5-HT

Answer 48

leucovorin

Question 49

L-24 Which chemical carcinogen is responsible for leukemia asbestos nitrosamines alkylating agents aromatic amines

Answer 49

alkylating agents

Question 50

L-24 Which DNA oncogenic virus is responsible for Burkitt's lymphoma HPV EBV HBV H. pylori

Answer 50

EBV

Question 51

L-25 Which drug is the most likely to cause peripheral neuropathy vinblastine 6-MP docetaxel vincristine

Answer 51

vincristine

Question 52

L-25 Which drug promotes microtubule polymerization vinblastine 6-MP docetaxel vincristine

Answer 52

docetaxel

Question 53

L-28 Acute passive venous congestion of the liver can be caused by Budd-Chiari syndrome hemothorax hypovolemic shock disseminated intravascular coagulation

Answer 53

budd-chiari syndrome

Question 54

L-28 What are the 5 causes of shock

Answer 54

``` cardiogenic hypovolemic septic neurogenic anaphylactic ```

Question 55

L-29 Omeprazole inhibits which of the below CYP2D6 CYP2C9 CYP2C19

Answer 55

CYP2C19

Question 56

L-29 In heparin-induced thrombocytopenia HIT which platelet protein is involved Platelet Factor (PF) 1 PF-2 PF-3 PF-4

Answer 56

PF-4

Question 57

L-30 What is a clinical feature of septic shock cool, pale skin flushed and warm skin patient confusion

Answer 57

flushed and warm skin

Question 58

L-30 What are the three components of virchow's triad

Answer 58

endothelial injury abnormal blood flow hypercoagulability

Question 59

L-31 In order to be considered a truly bactericidal agent MBC > MIC MBC < MIC MBC = MIC

Answer 59

MBC = MIC

Question 60

L-31 In order to be considered a bacteriostatic agent MBC > MIC MBC < MIC MBC = MIC

Answer 60

MBC > MIC

Question 61

L-32 What is a characteristic of a thrombus platelets not involved gelatinous not attached to the vessel wall lines of zahn

Answer 61

lines of zahn

Question 62

L-32 What is characteristic of a massive pulmonary thromboembolism sudden death dyspnea, pain asymptomatic

Answer 62

sudden death

Question 63

L-33 Which drug can be prescribed to children and pregnant women penicillin G penicillin V ampicillin amoxicillin

Answer 63

amoxicillin