Terms Flashcards

1
Q

dose

A

quantitative amount administered or taken by a patient for the intended medicinal effect

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2
Q

single dose

A

the amount taken at one time

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3
Q

daily dose/total dose

A

the amount taken during the course of therapy

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4
Q

dosage regimen

A

the schedule of dosing (ex. QID for 10 days)

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5
Q

usual adult dose

A

the amount that ordinarily produces the medicinal effect intended in the adult patient

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6
Q

usual pediatric dose

A

similarly defined for the infant or child patient

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7
Q

usual dosage range

A

the quantitative amounts of the drug that may be prescribed within the guidelines of usual medical practice

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8
Q

median effective dose

A

the amount that produces the desired intensity of effect in 50% of the individuals tested

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9
Q

median toxic dose

A

the amount that produces toxic effects in 50% of the individuals tested

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10
Q

loading dose

A

or priming dose, a larger than usual initial dose may be required to achieve the desired blood drug level

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11
Q

median effective concentration (mec)

A

the minimum concentration to produce the drug’s desired effects in a patient

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12
Q

minimum toxic concentration (mtc)

A

the concentration that produces dose-related toxic effects

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13
Q

monotherapy

A

referred to as the primary drug treatment

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14
Q

adjunctive therapy

A

additional to or supportive of a different primary treatment

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15
Q

prophylactic doses

A

administered to protect the patient from contracting a specific disease (ex. vaccines)

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16
Q

dosage forms

A

contain pharmaceutical ingredients which provide the physical features, stability requirements, and aesthetic characteristics desired for optimal therapeutic effects

17
Q

example of pharmaceutical ingredients

A

solvents, vehicles, preservatives, stabilizers, binders, fillers, disintegrants, flavorants

18
Q

number of doses calculation

A

number of doses = total quantity/size of dose

19
Q

size of dose calculation

A

size of dose = total quantity/number of doses

20
Q

total quantity calculation

A

total quantity = # of doses x size of dose

21
Q

In using the equation, the total quantity and the size of dose must be

A

in the same unit of measure.

22
Q

low-dose therapy

A

the administration of doses that are much smaller than the usual dose of a drug

*Use of Aspirin in 81-mg amounts (rather than the usual dose of 325 mg) to lower the risk of heart attack and clot-related stroke.

23
Q

high-dose therapy

A

the administration of doses that are much larger than the usual dose of a drug

*Commonly associated with the chemotherapeutic treatment of cancer

24
Q

2 types of dosing options

A

Low-dose therapy and High-dose therapy

25
Q

fixed-dose combination products

A

products containing two or more therapeutic agents in fixed-dose combinations

26
Q

advantages of fixed-dose combination products

A

two or more drugs may be taken in a single dose which may be more convenient, enhance compliance, and less expensive

27
Q

disadvantages of fixed-dose combination products

A

relative inflexibility in dosing compared with individual drug dosing

28
Q

tablet splitting and crushing

A

*a number of tablets are scored, or grooved, to allow breaking into approximately equal pieces (usually halves)

*allows dosage flexibility, particularly when a patient is started at a half dose and then is titrated up to a full dosage level

*also enables a patient to take a product at a strength that is not otherwise available

29
Q

dose measurement

A

It urges the use of a measuring device that either accompanies the product or is obtained separately and is calibrated to deliver the recommended dose

30
Q

general dose calculations

A

calculations for number of doses, size of dose, and total quantity