Terms- Schizophrenia

Question 1

Psychosis

Answer 1

refers to a total inability to recognize reality (e.g., delusions and hallucinations). is not a diagnosis but a symptom.

Question 2

Schizophrenia Etiology

Answer 2

Combination: Genetics and extreme nongenetic factors.

1. Brain structure abnormalities (neuroanatomical)
2. Neurochemical (brain chemistry) theories

Question 3

Prodromal

Answer 3

Pre-psychotic phase

Question 4

Acute Phase

Answer 4

Florid positive and negative symptoms; cognitive symptoms

Question 5

Stabilization

Answer 5

Decrease in severity

Question 6

Maintenance Phase

Answer 6

Symptoms in remission, with possible presence of milder, persistent residual symptoms.

Question 7

Positive symptoms

Answer 7

Above normal: Hallucinations, Delusions, Bizarre behavior, Catatonia, Formal thought disorder.

Question 8

Negative symptoms

Answer 8

Below normal: Apathy, Lack of motivation, Anhedonia, Blunted or flat affect, Poverty and speech (aphasia)

Question 9

Cognitive symptoms

Answer 9

Impairment in memory; disruption in social learning, Inability to reason, Inability to solve problems, Lack focus attention

Question 10

Mood symptoms

Answer 10

Depression, Anxiety, Demoralization, Dysphoria, Suicidality

Question 11

Delusions

Answer 11

False fixed beliefs not corrected by reasoning:
Thought broadcasting
Thought insertion
Thought withdrawal
Delusion of being controlled

Question 12

Thought broadcasting

Answer 12

the belief that others can hear or are aware of an individual’s thoughts

Question 13

Concrete thinking

Answer 13

Impaired ability to think abstractly, focused on the facts

Question 14

Loose association

Answer 14

jumbled thoughts incoherently expressed to the listener

Question 15

Neologisms

Answer 15

words that the patient makes up

Question 16

Clang association

Answer 16

rhyming

Question 17

Word salad

Answer 17

take the sentence and cut it up first work that comes to mind is what they say

Question 18

Echolalia

Answer 18

Pathologic repeating of another’s words

Question 19

Echopraxia

Answer 19

Mimicking the movements of another (Echolalia and echopraxia are common in catatonia.)

Question 20

Catatonia

Answer 20

A behavioral syndrome marked by an inability to move normally

Question 21

Waxy flexibility

Answer 21

when the patient holds a distorted posture for extended periods, as though the patient were molded in wax

Question 22

Depersonalization

Answer 22

refers to a feeling stated as feeling not as a person

Question 23

Conventional/ First generation Antipsychotics

Answer 23

Target + symptoms
trifluoperazine
(generic only)
thiothixene (Navane)	
fluphenazine (Prolixin)	
haloperidol (Haldol)	
pimozide (Orap)
chlorpromazine
(thorazine)
thioridazine (Mellaril)
loxapine (Loxitane)
molidone (Moban)
perphenazine (Trilafon)

Question 24

Unconventional/ Second generation Antipsychotics

Answer 24

Treat + & - symptoms: aripiprazole (Abilify), clozapine (Clozaril), olanzapine (Zyprexa), paliperidone (Invega)- can be an injection, quetiapine (Seroquel), risperidone (Risperdal), ziprasidone (Geodon), Latuda

Question 25

Extrapyramidal
Symptoms

Answer 25

Akathisia, Acute dystonia , Pseudoparkinsonism: pill rolling, shuffling gait, masklike facial expression, and drooling

Question 26

Treatment for EPS

Answer 26

trihexyphenidyl (Artane), benztropine mesylate (Cogentin), diphenhydramine hydrochloride (Benadryl), biperiden (Akineton), amantadine hydrochloride (Symmetrel)

Question 27

Dystonia

Answer 27

Stiff position, jaw thrust forward, tongue, face, neck, and back opisthotonos, drooling, oculogyric crisis

Question 28

Tardive dyskinesia

Answer 28

involuntary spasmodic muscular contractions that involve the tongue, smacking lips, licking, blowing, irregular movements of the arms, neck and shoulder, rocking hip jerks, pelvic thrusts are observed. movement of face, fingers toes neck, trunk or pelvis, it appears after prolonged treatment. The symptoms are frequently not reversible, even when the drug is discontinued

Question 29

Akathisia

Answer 29

evidence by internal and external restlessness, pacing and fidgeting

Question 30

Anticholinergic effects

Answer 30

Can't see, Can't pee, Can't poop

Question 31

ziprasidone (Geodon)

Answer 31

may prolong the QT interval, making it a poor choice for a patient with cardiac disease

Question 32

olanzapine (Zyprexa)

Answer 32

fosters weight gain

Question 33

Latuda

Answer 33

can cause weight gain, not good for diabetes, and cholesterol can be elevated but it does not cause as much tardive dyskinesia

Question 34

clozapine (Clozaril)

Answer 34

Clozapine may produce agranulocytosis, making it a poor choice as a first-line agent

Question 35

aripiprazole (Abilify)

Answer 35

Used for patients who have ^ glucose and hypertension

Question 36

paliperidone (Invega)

Answer 36

can be an injection, last 2-3 months