Test 1 Flashcards
What are the purposes of IV fluid replacement?
To restore lost fluid vol from the intravascular, shock, to give medications, and to have access incase of electrolyte emergencies
Total body fluids=
60%
Intracellular fluid is = to
2/3 the fluid vol in the body and 40-45%
extracellular fluid is = to
15-20% of total body fluids
- intersitial= 75% of the ECF
- Plasma=25% of the ECF
infants fluid content make up = …%
70%
Why do water imbalances increase in the elderly and infant population?
due to decreased skeletal muscle mass, more adipose tissue make up, infants have a smaller system that is still developing.
what is Osmoregulation?
a mechanism that uses gradients and semi permeable membranes to balance movement of solutes.
what is diffusion?
when particles move across a cellular membrane from high to low concentration.
What is Active transport?
Process requires ATP to activate a Na/K+ pump to move solutes against the gradient.
What is osmosis?
The movement of water over semi permeable membranes to areas of high solute concentration
What is filtration and where is it done?
Filtration can occur in the vascular system or the nephrons in the kidneys.
the vascular system using hydrostatic pressure to push fluids out of veins and into capillaries & uses oncotic pressure to pull water back into the arteriole.
The nephrons in the kidneys filter solutes, water, waste products making 180 L of fluids a day making 1-2 L of urine.
what is RAAS and How does RAAS work?
Renin-Angiotensin-Aldosterone-System
- Kidneys sense decreased blood flow at the Juxtaglomulerus–> stimulates the releases of renin from the liver–> renin stimulates the release of angiotensinogen which is converted to ang2 by ACE from the lungs—> Agn2= active form and causes vasoconstriction in the periphery bv—>Aldosterone is stimulated by the Vasoc coaused by Ang2—> Ald acts on the kidneys to reabsorb Na+ and water
when there is too much solute and water loss the cell will…
shrink ( hypertonic)
When there is too much solvent and not enough solute the cell will…
Swell ( hypotonic)
What does ANP do?
Atrial naturetic hormone is stimulated by increased stretch of the atria. ANP causes +GFR and promotes excretion.
What populations is regular dehydration common in?
children and elderly
What causes dehydration?
- fluid shift from the intracellular to extracellular–> interstitial –> vasculature
- N/v/d, poisoning, Heat stroke, sepsis,
what are some s/s of dehydration?
- alt LOA, thirst, dry mucous membranes, excessive skin turgor, lethargy, decreased urine output, Hypotension, Pale skin, orthostatic vitals
What causes over-hydration?
medication, fluid overload, urinary retention, too much fluid intake, kidney failure, chf, UTI
what are s/s of over hydration?
lung crackles, s/s or UTI, ascities, pulmonary and peripheral edema, SOB, weakness, lethargic, +bp,
What types of fluids can be used to replace fluid loss in the body?
crystalloids: ex: ringers lactate, 0.9%NaCl,
Blood products
colloids:
what does the 3:1 rule mean?
for every 1 unit vol lost it should be replaced with 3 unit vols of isotonic solution ( preferrably)
isotonic solutions of have a ph of what?
5.5
what are some common types of isotonic crystalloid?
ringers lactate
NS 0.9%
Dw5