Test 1 Flashcards

(48 cards)

0
Q

acute pain lasts LESS than 3-6 months and is usually associated with ____

A

nociceptive

nociceptive is either somatic or visceral

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1
Q

define pain

A

an unpleasant sensory AND emotional experience with actual OR potential tissue damage OR described in terms of such damage

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2
Q

nociceptive is either __ or __

A

somatic or visceral

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3
Q

chronic pain tends to be non-____

A

non-nociceptive

non-nociceptive is either neuropathic or idiopathic (psychogenic)

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4
Q

non-nociceptive is either __ or __

A

non-nociceptive is either neuropathic or idiopathic (psychogenic)

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5
Q

Somatic pain is well localized, sharp in nature, and generally hurts at the point or area of stimulus. Somatic pain is carried by __ fibers

A

type A fibers

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6
Q

Visceral pain is diffuse and can be referred to another area, dull, achy, vague. Probably carried by type __ fibers

A

C

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7
Q

Neuropathic pain is like when you hit your funny bone, it’s a shock. It’s __

A

abnormal

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8
Q

Idiopathic pain has no apparent cause, may be psychological aka ___

A

idiopathic aka psychogenic

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9
Q

define algesia

A

increased sensitivity to pain, the pain threshold is decreased

algae are VERY sensitive to pain

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10
Q

define algogenic

A

pain producing

OWWgogenic

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11
Q

define allodynia

A

a usually nonharmful stimulus that is perceived as painful

an aloe plant is usually harmless, but if you’ve never seen one before you might think it would be painful

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12
Q

define analgesia

A

the absence of pain in the presence of a normally painful stimulus

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13
Q

define dysethesia

A

an unpleasant painful abnormal sensation, whether evoked or spontaneous

the opposite of good anesthesia is dysethesia

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14
Q

define hyperalgesia

A

a hyper response to pain

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15
Q

define neuralgia

A

pain in the distribution or region covered by a peripheral nerve

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16
Q

define neuropathy

A

an abnormal disturbance in the function of a nerve

neuro-path

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17
Q

define paresthesia

A

an abnormal sensation, whether spontaneous or evoked

your patients will get a “pair of thesias” when you brush their nerve roots with your epidural catheter

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18
Q

somatic nociceptive pain is defined by four processes

A

transduction, transmission, perception, and modulation

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19
Q

define transduction

A

the TRANSFORMATION of a stimulus into an action potential

20
Q

define transmission

A

the PROCESS by which an action potential is conducted from the periphery to the CNS

21
Q

define perception

A

involves the signal being RECOGNIZED by various areas of the brain

22
Q

define modulation

A

ALTERATION of afferent activity, either SUPPRESS or ENHANCE

23
Q

Which two fibers are the primary afferents involved in transduction?

A

myelinated A-delta and non-myelinated C fibers

A/c

24
How fast are myelinated A-delta fibers?
6-30 meters / second Delta airplane fly between 6-30 meters per second
25
how fast are non-myelinated C fibers?
1/2 - 2 meters per second
26
Don't forget that the __ neuron ascends several spinal segments before it synapses with the secondary neuron, which then crosses to the other side of the spinal cord and ascends to the thalamus
Primary
27
The synapse between primary afferents and secondary neurons is primarily in Lamina of Rexed 1, 2, and __
5
28
Wide dynamic range neurons receive input from both nociceptive (A-delta and C) AS WELL AS non-nociceptive (A-beta) neurons cause ___
central sensitization or chronic neuropathic pain.
29
anterolateral pathway of the spinothalamic tract ascends to the __
lateral thalamus
30
somatic nociceptive pain is defined by four processes
transduction, transmission, perception, and modulation
31
define transduction
the TRANSFORMATION of a stimulus into an action potential
32
define transmission
the PROCESS by which an action potential is conducted from the periphery to the CNS
33
define perception
involves the signal being RECOGNIZED by various areas of the brain
34
define modulation
ALTERATION of efferent activity, either SUPPRESS or ENHANCE
35
Which two fibers are the primary afferents involved in transduction?
myelinated A-delta and non-myelinated C fibers | A/c
36
How fast are myelinated A-delta fibers?
6-30 meters / second Delta airplane fly between 6-30 meters per second
37
how fast are non-myelinated C fibers?
1/2 - 2 meters per second
38
Don't forget that the __ neuron ascends several spinal segments before it crosses to the other side of the spinal cord and ascends to the thalamus
secondary
39
The synapse between primary afferents and secondary neurons is primarily in Lamina of Rexed 1, 2, and __
5
40
Wide dynamic range neurons receive input from both nociceptive (A-delta and C) AS WELL AS non-nociceptive (A-beta) neurons cause ___
central sensitization or chronic neuropathic pain.
41
anterolateral pathway of the spinothalamic tract ascends to the __
lateral thalamus
42
Modulation =
descending
43
Pain modulation is enhanced in the presence of __
central sensitization remember, modulation can be either suppression or enhancement, so sensitization plays right along with that.
44
endogenous opioids such as endorphins, dynorphins, and enkephalins are ___
inhibitory
45
what are the two excitatory neurotransmitters?
substance P and glutamate
46
what is the special receptor for glutamate?
NMDA where ketamine works
47
what are the five inhibitory neurotransmitters?
glycine, GABA, enkephalin, serotonin, and norepinephrine GGESN