test 1.2

Question 1

what are the three ways drugs are identified by

Answer 1

(1) Chemical-longer, refers to chemical structure; Ex-Paracetamol 
(2) Generic-shorter; derived from chem. name; Ex-Acetaminophen  (3)Trade-brand name assigned by the manufacturer; Ex-Tylenol

Question 2

what is pharmacokinetics

Answer 2

The study of the impact of the body on drugs or how the body
acts on drugs

Question 3

what are the 4 areas of pharmacokinetics

Answer 3

-Absorption -Distribution -Metabolism -Elimination/Excretion

Question 4

true or false
Patient related factors such as (Genetic makeup, sex, age, obesity) may also influence the rate at which a drug is processed.

Answer 4

true

Question 5

true or false
Drugs in solid form must dissolve in order to be absorbed into
systemic circulation

Answer 5

true

Question 6

what is a substance with no therapeutic value
used to disperse or administer the active drug; controls delivery rate and manner in which it is
absorbed called

Answer 6

drug vehicle

Question 7

what are the two routes to administrate a drug

Answer 7

Enternal or Parenteral(Nonenteral)

Question 8

what is enteral

Answer 8

–by way of alimentary canal or digestive system

Question 9

what is parental (nonenteral)

Answer 9

usually delivered to target tissue

Question 10

true or false

both routes Enternal and Parenteral(Nonenteral) produce the same effect

Answer 10

false because each has inherent advantages and disadvantages

Question 11

what three routes of administration has the most immediate effect

Answer 11

Sublingual (SL), Inhalation, Intravenous (IV)

Question 12

what are the 5 things that routes are determined by

Answer 12

1. Ease of administration - ex. age
2. Patient adherence - ex. level of consciousness
3. Desired onset of action - ex. immediate vs time delayed
4. Local vs systemic distribution - ex. intra-articular vs oral
   anti-inflammatories
5. Drug properties - ex. insulin is injected b/c it is
   destroyed in the GI tract

Question 13

explain bioavailabilty

Answer 13

Rate and extent of which the drug (active metabolite) is

absorbed

Question 14

explain bioequivalence

Answer 14

Different formulations of the same drug (ie. generic) are

bioequivalent if the bioavailability of the 2 drugs are the same

Question 15

with oral administration does tabs or caps act faster than liquids?

Answer 15

No liquids act the fastest

Question 16

true or false

Execrise increases absorption of medicine

Answer 16

false

Question 17

true or false

liquid delays up absorption, food in stomach speeds absorption

Answer 17

false

Liquids speed it up and food slows it down

Question 18

what is the first pass effect

Answer 18

Drug is absorbed in GI tract and carried to

the liver before it reaches the blood stream

Question 19

true or false
Drugs are not evenly distributed throughout
body

Answer 19

true

Question 20

what does high volume of distribution and low plasma concentration cause

Answer 20

drug

more greatly distributed in extravascular spaces

Question 21

does higher body weight equal higher or lower volume fo distribution csusign lower or higher blood concentration

Answer 21

Higher body weight equals higher volume of

distribution and therefore lower blood concentration

Question 22

what is the site and action of a drug (explain site)

Answer 22

The “site” is the target receptor on the cell

surface or inside a specific cell type

Question 23

what is the site and action of a drug (explain action)

Answer 23

The “action” is biological response caused

by the active drug or metabolite