Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Bloodbank > Test 2 > Flashcards

Test 2 Flashcards

1
Q

What are 3 antigens in the P group?

A

P1, P2, and Pk

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What antigens do you have if you are a P1 phenotype?

A

All three P antigens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What antigens do you have if you are a P2 phenotype?

A

P and Pk (missing P1)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What does it mean if you have the null phenotype for the P system?

A

You do not carry the P1, P2, or Pk

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What antibodies are naturally occurring in Pnull people?

A

Anti-P1, Anti-P2, and Anti-Pk

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Is Anti-P1 naturally occurring? And what kind of people can this antibody be found in?

A

Yes and P2 people

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Is Anti-P1 IgG or IgM?

A

IgM (cold reacting)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Can Anti-P1 bind with complement?

A

Yes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Individuals negative for the I antigen are labeled?

A

i

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

After you’re born, i converts to I antigen. This process is usually complete by?

A

18 months

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Is Anti-I clinically significant?

A

No

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Is Anti-I IgM or IgG?

A

IgM (cold reacting)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

In the MNS system, what genes are allelic to each other?

A

M and N

S and s

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Is anti-M IgM or IgG?

A

IgM (cold reacting)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Is Anti-M naturally occuring?

A

Yes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Does Anti-M bind complement?

A

No

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Does Anti-M exhibit a dosage effect?

A

Yes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Is Anti-N IgM or IgG, naturally occuring, bind with complement, exhibit dosage effects?

A

IgM, and yes it is naturally occurring, binds with complement, and exhibits dosage effects.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Is Anti-S and Anti-s naturally occuring?

A

No, RBC stimulated through transfusion of pregnancy.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Is Anti-S and Anti-s IgM or IgG?

A

IgG (warm reacting 37 degrees)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Why is Anti-U clinically significant and what race is it seen in?

A

Associated with HDFN and HTR (Hemolytic Transfusions Reactions) and African Americans

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

How many antigens does the Kell system contain?

A

24

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What is Ku or Total Kell?

A

Represents all Kell antigens collectively

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

What is Ko (Kell null)?

A

Lacks entire Kell glycoprotein and all Kell antigens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
What are the antigens for Fisher-Race?
D, C, E, c, e
26
What are the antigens for Wiener?
R1, R2, R0, Rz, r', r'', ry
27
What is the clinical significance of a weakened D person who has donated blood?
The donor is considered positive for the D antigen.
28
What is the clinical significance of a weakened D person who is going to receive blood?
That person should receive D negative blood because they are considered weakly positive for D.
29
When is anti-human globulin used?
During IAT and DAT testing to detect antibodies in serum (IAT) or detect coating of RBCs with antibodies (DAT).
30
List the antigens/antibodies for the ABO blood group.
A1, A2, B (Antigens) | Anti-A, Anti-B, Anti-A1, Anti-A,B, Anti-H (Antibodies)
31
List the antigens/antibodies for the Rh blood group.
D, C, E, c, e (Antigens) | Anti-D, Anti-C, Anti-E, Anti-c, Anti-e (Antibodies)
32
List the antigens/antibodies for the Kell blood group.
K, k, Kpa, Kpb, Kpc, Jsa, Jsb (Antigens) Anti-K, Anti-k, Anti-Kpa, Anti-Kpb, Anti-Kpc, Anti-Jsa, Anti-Jsb (Antibodies)
33
List the antigens/antibodies for the Kidd blood group.
Jka, Jkb (Antigens) Anti-Jka, Anti-Jkb (Antibodies)
34
List the antigens/antibodies for the Duffy blood group.
Fya, Fyb (Antigens) Anti-Fya, Anti-Fyb (Antibodies)
35
List the antigens/antibodies for the Lutheran blood group.
Lua, Lub (Antigens) Anti-Lua, Anti-Lub (Antibodies)
36
List the antigens/antibodies for the P blood group.
P1, P, PK (Antigens) Anti-P, Anti-P1, Anti-Pk (Antibodies)
37
List the antigens/antibodies for the I blood group.
I (Antigen) Anti-I, Anti-i (Antibody)
38
List the antigens/antibodies for the MNS blood group.
M, N, S, s, U (Antigens) Anti-M, Anti-N, Anti-S, Anti-s, Anti-U (Antibodies)
39
List the antigens/antibodies for the Lewis blood group.
Lea, Leb (Antigens) Anti-Lea, Anti-Leb (Antibodies)
40
What is the purpose of a DAT (Direct Antiglobulin Test)?
Detect sensitized cells in vivo
41
Define DAT.
Direct Antiglobulin Test
42
What is the reagent for Anti-Human Globulin?
Antibody to human globulin
43
What percentage of people are Rh+?
85%
44
Most common Lewis phenotype?
Le (a-b+)
45
Most common P phenotype?
P1
46
Most common Kell phenotype?
kk (small k) | K-k+
47
Most common Duffy phenotype in whites?
Fy (a+b+)
48
Most common KIDD phenotype in blacks?
Jk (a+b-)
49
Three causes of a false positive DAT.
- Complement (EDTA tube was not used and complement was not inactivated) - Improper centrifugation (cells too tight, not easily dispersed) - Cells agglutinated prior to washing
50
List Ig class, best reaction temperature, and phase of ABO blood group antibodies.
IgM 22-24 degrees Celsius Not IAT
51
Ig class, best reaction temperature, and phase of Rh blood group antibodies.
IgG 37 degrees Celsius IAT
52
Ig class, best reaction temperature, and phase of Kell blood group antibodies.
IgG 37 degrees IAT
53
Ig class, best reaction temperature, and phase of Kidd blood group antibodies.
IgG 37 degrees IAT
54
Ig class, best reaction temperature, and phase of Duffy blood group antibodies.
IgG 37 degrees IAT
55
Ig class, best reaction temperature, and phase of Lutheran blood group antibodies.
IgM 22-24 degrees Not IAT
56
Ig class, best reaction temperature, and phase of I blood group antibodies.
IgM 4-22 degrees Not IAT
57
Ig class, best reaction temperature, and phase of MNS blood group antibodies.
IgG 37 degrees IAT
58
Ig class, best reaction temperature, and phase of Lewis blood group antibodies.
IgM 4-22 degrees Not IAT
59
DCe
R1
60
DcE
R2
61
Dce
R0
62
DCE
Rz
63
ce
r
64
Ce
r'
65
cE
r''
66
CE
ry
67
Three causes of false negative DATs.
- Neutralization of AHG reagent - Improper procedures (too heavy rbc concentration, improper cells) - Interruption in testing
68
What is the CIS effect?
Genes in the sis position are on the same chromosome of a pair of homologous chromosomes.

Bloodbank (1 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions