Test 2- Analgesics Flashcards
(26 cards)
Psychological element, in head a little bit. Might be different on different days
Pain tolerance
Physical element, how much pain can you take
Pain threshold
An example is low-back pain
Chronic pain
An example is a kidney stone or appendicitis
Acute pain
What is the role of adjuvant therapy
Assist primary agents in relieving pain by using smaller doses of pain medicine
What does adjuvant therapy do?
Decreases side effects
Approaches pain stimulus from another mechanism which is synergistic effect (work together to achieve a better outcome)
Need progressively higher doses to maintain same analgesic effect
Drug tolerance
What is drug tolerance common in
Narcotics
Works really good for awhile then same dose doesn’t give you same effect as it used to so you have to bump up dose
Pattern of compulsive drug use; euphoria rather than pain relief
Drug dependence
Physiological
Physical sign of drug dependence
Sudden withdraw of medication=withdraw symptoms
Withdraw symptoms
Rebound pain, tachycardia, elevated BP, metal agitation
Opioid withdraw symptoms
Anxiety, irritability, chills, hot flashes, joint pain, N/V, abdominal cramps, diarrhea
What is a PCA
Patient controlled analgesia
-smaller doses that can be given more frequently
Problem: family members pushing button when they think the person needs it
Opioid analgesics are all considered ________ and need what three things
Controlled substances
- dr has to write prescription
- DEA #
- no refills
What are the opioid receptors
mu, kappa, sigma, delta, epsilon
What are endorphins
Endogenous morphine
*natural internal mechanism of pain control
“Runners high”
Opioid agonist are also known as
Narcotics
What is the mechanism of action of opioid agonist
- achieve beneficial effects by their actions on the CNS
- also act outside the CNS, which is where unwanted effects occur
Indications of opioid agonists
Alleviate severe to moderate pain Cough suppressant- codeine, hydrocodone Antidiarrheal preparations (because one of side effects is constipation)
Contraindications of opioid agonists
- Allergy
- Severe asthma, respiratory
- conditions involving elevated intracranial pressure (ICP)
- pregnancy
Side effects of opioid agonists
Sedation, constipation, respiratory depression, Euphoria, “high”, dizzy
Interactions of opioid agonists
Co administration with alcohol, antihistamines, barbiturates, benzodiazepines, phenothiazine, or other CNS depressants= additive respiratory depressant effects
Examples of opioid agonists
Morphine Dilaudid Demerol Codeine Oxytocin Ultram
What are Combination Opioid Analgesics
- Very common by mouth narcotics
- Narcotics that are combined with aspirin (ASA) acetaminophen (APAP, Tylenol)
- work synergistically with the narcotics
- use less narcotics