Test 2 Meds - Cancer & HIV Flashcards

(47 cards)

1
Q

Antineoplastic
agents 2 examples

A

Doxorubicin and Vincristine

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2
Q

Doxorubicin type of drug

A

Anti-tumor
antibiotic

Anthracyclines

Cell cycle non-specific

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3
Q

Doxorubicin acute side effect

A

Bone Marrow Suppression

Nausea and vomiting

Stomatitis,

Red urine and tears

Alopecia,

Cardio-toxicity,

CHF

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4
Q

Doxorubicin delayed or chronic side effects

A

Cardiomyopathy, CHF

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5
Q

Doxorubicin Nursing Considerations

A

Administer antiemetics prior to
treatment.

Monitor EKG and echo

Monitor for extravasation- central line preferable

Monitor for chest pain and

SOB

Monitor WBC, ANC (neutrophil count), platelets, Hbg &Hct, liver enzymes

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6
Q

Doxorubicin Patient Teaching

A

Good oral hygiene,

No alcohol in mouthwash

Notify Provider for SOB or CP

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7
Q

Vincristin type of drug

A

Vinca alkaloid
Cell cycle specific

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8
Q

Vincristine side effect

A

Weakness, paresthesia,
sensory loss &
decreased reflexes

alopecia

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9
Q

Vincristine Nursing Considerations

A

Monitor for extravasation-
central line preferable

Monitor WBC, ANC, platelets,
Hbg &Hct
Liver enzymes

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10
Q

Vincristine Patient Teaching

A

Advise to report side effects
Good mouthcare

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11
Q

Biological and Targeted Therapies Examples

A

Trastuzumab
Imatinib
Filgrastim
Erythropoietin

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12
Q

Rastuzumab used in

A

Targets those breast cancer cells that have an over expression of the HER
protein

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13
Q

Rastuzumab type of therapy and how is it given

A

MOAB
IV

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14
Q

Rastuzumab Side Effects

A

Nausea and vomit

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15
Q

Rastuzumab Nursing Considerations

A

Monitor:
Hypersensitivity reaction,
Cardio toxicity,
Tachycardia,
CHF,
Dyspnea and edema,
Monitor fluid status

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16
Q

Rastuzumab Patient Teaching

A

Report SOB and chest pain

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17
Q

Imatinib used in…

A

Chronic myeloid leukemia (CML)

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18
Q

Imatinib type of drug and how is it given

A

Tyrosine Kinase inhibitor
po

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19
Q

Imatinib Side effects

A

GI discomfort,
Nausea and vomit
Flu like symptoms

20
Q

Imatinib Nursing considerations

A

Take with food,
give anti medic
Tylenol for mild symptoms
Monitor K levels, for edema,
CBC for neutropenia

21
Q

Imatinib Patient Teaching

A

Hygiene to prevent infection

22
Q

Filgrastim what does it do how is it given?

A

Decrease risk of infection
Increase neutrophil
SQ

23
Q

Filgrastim side effects

24
Q

Filgrastim Nursing considerations

A

Monitor CBC
Tylenol for pain

25
Erythropoietin what does it do how is it given?
Increase the production of RBC’s SQ
26
Erythropoietin Side effects
Increased BP body aches
27
Erythropoietin Nursing Considerations
Monitor HBG, head aches,
28
Hormonal Therapy Examples
Leuprolide Tamoxifen
29
Leuprolide why is it used?
Used instead of surgical castration Stops the testes from producing testosterone
30
Leuprolide how is it given?
Given Sq or IM
31
Leuprolide Drug class
Gonadotropin releasing hormone agonist Stops the testes from producing testosterone
32
Leuprolide side effects
Hot flashes, decreased libido, & gynecomastia Monitor for dysrhythmia and assess pulmonary edema
33
Leuprolide Nursing consideration
Increase Ca ++ and vit D in diet, exercises to increase bone density Monitor PSA
34
Tamoxifen Drug class
Selective estrogen receptive modulator Estrogen receptor blocker
35
Tamoxifen how does it work
Attaches to hormone receptors in breast cancer cells (The cancer can’t access the hormone it needs to grow)
36
Tamoxifen how is it given
orally
37
Tamoxifen Side effects
Nausea and vomit Pulmonary Embolism, hot flashes
38
Tamoxifen Nursing Considerations
Monitor for abnormal bleeding Monitor Ca+2 levels, Cataracts, retinopathy
39
Cytoprotectants
Amifostine and mesna
40
Apetite stimulant
Megestrol
41
Suppress production of Stephen and testosterone
Goserelin
42
Estrogen receptor down regulators
Induce degradation of estrogen receptors
43
Estrogen antagonist
Tamoxifen Anastrozole Trastuzumab
44
Biological response modifiers
Interleukin Interferon
45
Types of immune therapy
Biological response modifiers Monoclonal antibody Targeted therapy Cancer vaccines
46
The only fda approved cancer vaccine
Sipuleucel-T For prostate cancer
47
Phototherapy is used in what type of cancer
Esophageal ocular tumors. Upperairway tumors No melanoma skin cancer