Test #2 (PDA, PPHN, Cardiac probs, Hydrops) Flashcards

(72 cards)

1
Q

Which of the following lesions results in active congestions of the pulmonary vasculature?

A

Truncus arteriosus

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2
Q

The most common heart defect presenting in the first 24 hours of life with cyanosis and increased vascularity is

A

transposition of the great arteries

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3
Q

Other defects associated with d-transposistion of the great arteries include?

A

aortic arch defects

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4
Q

Congestive heart failure develops early in d-transposition of the great arteries in the presence of?

A

PDA or VSD

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5
Q

What shape of the heart is characteristic of TGA on chest x-ray?

A

egg

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6
Q

In cases of d-TGA, the aortic arch is usually?

A

left-sided

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7
Q

Heart Failure typically presents at ____ days in cases of coarctation of the aorta

A

7-14day

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8
Q

Which type of coarctation is typically identified in the neonatal periods?

A

preductal

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9
Q

In coarctation of the aorta with a discrete constriction the constriction typically occurs at the opposite side of the insertion of the

A

ductus arteriosus

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10
Q

Congestive heart failure causes by coartation of the aorta is exacerbated by the presence of

A

VSD or PDA

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11
Q

X-ray findings consistent with coarctation of the aorta include which of the following heart shapes?

A

Globular

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12
Q

In the presence of T of F with pulmonary atresia, pulmonary perfusion may be supplied by flow through a

A

PDA

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13
Q

The timing of the presentation of TOF is dependent on the degree of

A

Right ventricular outflow obstruction

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14
Q

Initial signs of TOF in the NB period inculde

A

respiratory distress, cyanosis, murmur

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15
Q

TOF includes which of the following findings?

A

Pulmonary stenosis

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16
Q

Chest x-ray findings in TOF include pulmonary arteries which appear>

A

thin and stringy

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17
Q

The heart size in an infant with TOF is typically

A

Normal or slightly enlarged

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18
Q

Infant with TOF, the heart assumes which shape?

A

Boot

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19
Q

Congestive heart failure accompanies TOF in the presence of

A

Tricuspid regurgitation

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20
Q

Clinical presentation of pulmonary atresia with intact septum include which of the following?

A

severe cyanosis, mild tachypnea, murmur

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21
Q

In cases of pulmonary atresia with intact Ventricular septum the cardiac size is dependent on the

A

amount of tricuspid regurgitation

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22
Q

In obstructive lesions, cardiomegaly occurs because of

A

hypertrophy

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23
Q

The greatest source of error in interpreting cardiac size is

A

poor inspiration

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24
Q

the neonate’s heart is normally globular at birth because the

A

right ventricular is enlarged (in adults its smaller than the left ventricular)

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25
In the neonate what is the normal orientation of the heart in the chest cavity?
almost equally to the R and L of the mediastinum
26
An LGA infant with hypertrophic cardiomyopathy (IDM) with have what heart issue?
LV outflow obstruction
27
Cynosis in the Neonate will have decrease pulmonary blood flow bc of what heart defect?
tricuspid atresia
28
what do infants do to compensate for decrease cardiac output?
Increase HR (CO=SV x HR)
29
What is a sign of diminished CO?
poor peripheral pulses
30
What are 3 medical mgnt of CHF?
Fluid restriction, daily wt, follow electrolytes
31
What would you do if the sats remain
Start Prostin
32
What are the 4 combinations of defects in TOF?
Pulmonary stenosis, Ventricular stenosis, over-riding aorta, Hypertrophy of R Ventricle
33
What defect AO originates from R vent and PA from LV?
Transposition of the Great Vessels
34
What defects of more common in term males 2:1
Transposition of the Great Vessels
35
What treatment is recommended for Transposition of the Great Vessels?
Prostin first and then balloon septostomy to improve interatrial mixing
36
when the BP is >15mmHg higher in the upper than the lower?
Coarctation of aorta
37
What defect is when the RV supplies pulmonary and systemic blood flow via PDA?
HPLHS
38
What happens when the PVR starts to decrease in an ASD?
L to R shunt develops
39
What are two major SE of Prostin?
Temperature increase (fever) and Apnea
40
In PPHN what causes hypoxemia?
extrapulmonary R to L shunting to the FO/ PDA
41
What is the oxygen index equation?
FiO2 X mean airway pressure / Postductal PaO2 = 100
42
What obstruction may have transient improvement with iNO followed by deterioration
Pulmonary venous obstruction
43
iNO causes toxicity by hemoglobin turning into Methemoglobin then causing ____
tissue hypoxia
44
What is another name for PDA; it links main pulmonary artery with descending aorta?
Fetal Ductus
45
What is the PATHOphysiology of PDA?
resistance of pulmonary and systemic circulations
46
What is the #1 mngt for PDAs?
fluid restriction
47
What is the respiratory mngt for PDA is already on vent?
Increase CPAP or iTime
48
What are 4 transient SEs of indomethacin?
- Renal dysfunction (decrease renal output) - hyponatremia (dilutional) - Plt dysfunction - Displacement of bili from sites
49
What are 3 contraindications for tx with indomethacin?
Cr > 1.7mg/dL BUN > 25mg/dL Plt
50
What causes hydrops in the fetus?
when there is an Rh incompatibility btwn mom and fetus. Anti-D (Rh alloimmune hemolytic diesease
51
What is when there is generalized total body edema with no hepatoslpenomegaly or abn erythropoiesis?
Non-immune hydrops
52
What is another name for non-immune hydrops?
fetal Anasarca
53
Decrease the pathophysiology of hydrops.
low colliod oncotic pressure from low albumin (fluid can't come into vessels) and high hydostatic pressure in caps (leaky caps)
54
What is a condition assoc. with Turner's Syndrome with dilation of pulmonary lymphatics that causes pleural effusions?
Lymphangiectasis
55
What is a virus that could cause fetal hydrops?
parvovirus (5th disease)
56
What is the most common cause of hydrops (25%)?
Cardiac probs - SVT, Congenital heart block
57
How do you treat fetal Tachy in hydrops?
Maternal dig - propranolol
58
What shape does the chest make with hydrops?
Bell shaped
59
What are the first two steps when resuscitating a hydrops infant?
``` #1 - establish airway #2 - Place lines ```
60
When is the fetal gut anatomically complete?
20-22 weeks
61
When is the most abundant weight gain in an infant's life?
between 26-36 weeks
62
Protein malnutrition in utero causes what in an infant?
Decrease pancreatic cells and insulin secretion, and increase in BP
63
What are two long term effects of poor growth?
Short stature and poor neurodevelopmental outcomes
64
How much protein (AA) should be started on day 1 to prevent a neg nitrogen balance??
1.5-2 gm/kg/day
65
What is a negative effect of delaying the onset of enteral feedings?
late onset sepsis
66
When should you start to fortify Human milk?
when you reach 100ml/kg/day
67
What are the normal lab values for | BUN, Albumin, TP, and Ca
BUN 5-20 Album 3.9-5 TP 6.3-7.9 Ca 7-12
68
What is the main consequence of low Ca?
bone demineralization, with increase in Alk phos, and decrease in length
69
What type of milk offered no benefit over preterm formula?
Pasteurized donor milk
70
What type of formula is not good for growing preemies and has poor protein quality
Soy formula
71
What is the recommended enteral protein intake?
3.5gm/kg/day
72
When should parenteral nutrition be maintained?
when enteral feeding are less than 80 CAL/kg/d