test 3 Flashcards
(95 cards)
why is left ascending artery the widow maker
supplies to left ventricle. If left ventricle doesn’t get enough oxygen… deadly.
Major causes of CAD
atherosclerosis- cholesterol plays a major role, as well as endothelial injury causing obstruction
what does a high CRP indicate
inflammation. typically elevated in CAD patients
collateral circulation
small arteries are built around the blocked artery in CAD, but they don’t deliver much oxygen and are only temporary solution, as chronic ischemia will soon occur
non modifiable risk for CAD
age, gender, genetics, ethnicity, family history
modifiable risk factors of CAD
Lipid levels, HTN, smoking, physical inactivity, obesity, diabetes, metabolic syndrome, psychological states, substance abuse
modifiable risk factors of CAD
Lipid levels, HTN, smoking, physical inactivity, obesity, diabetes, metabolic syndrome, psychological states, substance abuse
common symptoms in CAD
edema, clubbing, chest pain with exertion, dizziness, nausea, dysrhythmias, low o2 sat
- diabetes patients may not feel chest pain or any pain as there nerves could be damaged
CAD diagnostics
Lipid panel, cholesterol, A1C, ECG, stress test, echocardiogram, chest x ray, bruits
drugs for CAD
> antihypertensives (beta blockers- lol, CCB- pine, Ace inhibitors - pril). monitor bradycardia and hypotension
> antianginals (nitroglycerine)
> lipid lowering (statins -monitor liver damage and myopathy)
> decrease cholesterol absorption - Ezetimibe (zetia)
> anticoagulants (heparin, warfarin) monitor for bleeding and thrombocytopenia (low platelets)
Coronary artery bypass graft (CABG)
take artery/vein from other place in body and attach to heart
2 wound- chest and where it was harvested
assess platelets, perfusion assessment of all organs, wound care, pain
Go into depression screening- link between getting CABG and depression
PTCA (percutaneous transluminal coronary angioplasty)
balloned catheter supresses plaque, allowing more space for blood to flow. stent may also be placed to prevent it from happening again
angina
intermittent chest pain usually occurring with the same pattern and intensity over period of time usually caused by CAD.
not enough oxygen. we want to decrease o2 demand and/or increase oxygen supply
happens when artery is 70% blocked or left main artery is 50% blocked
risk factors for angina
same as CAD, but oral contraceptives are added as well as menopausal women
short acting nitrates
dilates peripheral and coronary blood vessels
- given sublingually or by spray
can take up to 3 doses; 5 mins apart
- for angina
long acting nitrates
to reduce angina incidence
side effects- headaches, orthostatic hypotension
stable angina diagnostics
chest x ray
12 lead ecg
lab studies
echocardiogram
exercise stress test
EBCT or CCTA (test that look for plaque using IV contrast)
cardiomyapthies
diseases that directly affect myocardial structure or function
- makes it hard for blood to be delivered to body
primary: idiopathic, only partially affected muscle
secondary- caused by known primary disease
can be ischemic - MI (reduced EF), CAD
or nonischemic - dilate, hypertrophic, restrictive
ejection fraction
Percentage of blood and volume left ventricle pushes out, normal is 55% and above
preload
volume coming into ventricle
increased in hypervolemia, regurgitation of valves
diuretics can help
afterload
resistance left ventricle must overcome to push blood
increased in HTN or vasoconstriction
- creates more workload
vasodilators can help
hypertrophic cardiomyopathy
thickened left ventricular wall, becomes stiff
- contraction isn’t weakened, but filling is impaired
can be genetic, or can happen in athletes
blood backs up into lungs
dilated cardiomyopathy
enlargement of left ventricle
- most common one
poor systolic function
decreased EF
as disease progresses, atrial enlargement
blood stays in LV… worry about clots
no specific cause,,, alcohol, epstein barr, radiation
restrictive cardiomyopathy
rigid ventricular walls: impaired filling and stretch
- least common type
etiology unknown
EF may be normal
heart tissue replaced by fibrosis. could lead to HF or dysrhythmias