Test 3 Flashcards

(53 cards)

1
Q

To create nucleotides is sugar (deoxyribose) connected with the phosphate group?

A

Yes

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2
Q

What are the ways that bases are always connected?

A

Adenine with thymine, and cytosine with guanine

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3
Q

What is the difference in structure between pyrimidines and purines?

A

Pyrimidines: single ringed, whereas purines are double ringed

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4
Q

Does the two of them bonding together help form the double helix structure of DNA?

A

Yes

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5
Q

What are the three parts of a nucleotide?

A

Sugar, phosphate group, and nitrogenous base

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6
Q

Does the nitrogenous base make a difference of what nucleotide you’re working with?

A

Yes

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7
Q

Is the backbone of DNA and RNA held together by covalent bonds?

A

Yes

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8
Q

Which of ATCG are pyrimidines/purines?

A

Pyrimidines: thymine, and cytosine. Purines: adenine, and guanine.

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9
Q

Do hydrogens bond with different bases?

A

Yes

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10
Q

Does the antiparallel structure refer to the two strands of DNA?

A

Yes

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11
Q

What does it mean when it is said that the two strands are antiparallel?

A

One strand runs in the 5’ to 3’ direction, while the other runs in the 3’ to 5’ direction

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12
Q

Does the 5’ end have a phosphate group attached to the 5’ carbon of the sugar?

A

Yes

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13
Q

What does the 3’ end have?

A

A hydroxyl group (-OH) attached to the 3’ carbon of the sugar

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14
Q

What did Griffith’s experiment demonstrate?

A

Genetic transformation in bacteria

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15
Q

Did he use two strains of streptococcus pneumonia to determine whether there was genetic transformation?

A

Yes

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16
Q

Was there a smooth but caused disease strain, as well as a rough and did not cause a disease?

A

Yes

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17
Q

Recall the experiment

A

S strain and R strain were both given to two different mines. The R-strain one survived whereas the one with the R-strain did not. The S strain was then heated and tested on another mouse, and a mix of the heat killed strain and R strain was given to the mouse given to mouse and died

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18
Q

Did Watson and Crick’s model provide the first accurate understanding of the double helix structure?

A

Yes

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19
Q

Was Franklin able to take the DNA and identify the double strand model?

A

Yes

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20
Q

Did the Meselson and Stahl experiment provide definitive evidence that DNA replication is semiconservative?

A

Yes

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21
Q

What does DNA replication being semiconservative mean?

A

Each new DNA molecule consists of one old (parental) strand and one newly synthesised one

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22
Q

Did Meselson and Stahl grow strands with medium and isotopes?

23
Q

What type of DNA molecules would conservative replication give you?

A

One DNA molecule would consist of two original strands, and the other would consist of two newly synthesized strands

24
Q

What is the process of DNA moving to the mRNA called?

A

Transcription

25
What is the movement from mRNA to proteins called? What does it use?
Its called translation and uses tRNA and rRNA
26
Is RNA pulling the double strands apart responsible for transcription?
Yes
27
Does RNA synthesis begin at the start site of the gene, and RNA polymerase adds RNA nucleotides complementary to the DNA template strand until termination?
Yes
28
What must ribosomes contain to turn mRNA into protein?
rRNA
29
What is tRNA responsible for?
Each tRNA enables the translation of a given mRNA codon into a certain amino acid
30
What is a codon?
A sequence of three consecutive nucleotides in a DNA/RNA that codes for a specific amino acid
31
For translation to occur does the tRNA bring the appropriate amino acids to the ribosome based on the mRNA's codons?
Yes
32
What is the ribosome's job?
Ensures proper assembly of the growing polypeptide chain until the entire protein is synthesised
33
What are the two main structures responsible for translation?
Ribosomes, and tRNA
34
What is the genetic codes?
Set of rules by which the information encoded within DNA or RNA is translated into proteins
35
What is the promoter?
Region of DNA located at the beginning of the gene which acts as a binding site for RNA polymerase
36
Who is the father of genetics?
Gregor Mendel
37
State 5 reasons why peas are used a model for Mendelian genetics
Easy for pollination, really fast to reproduce, ethically acceptable, easy for germination, and easy to see phenotypes
38
What are the three principles of Mendelian genetics?
Dominant and recessive, segregation, and independent assortment
39
Do organisms inherit two copies of each gene, one from each parent, with one allele normally being dominant and the other being recessive?
Yes
40
What is segregation?
When meiosis makes sex cells, each cell has only one allele
41
What does independent assortment mean?
Each trait is passed on independent of other traits
42
What is the difference between dominant and recessive?
Dominant is expressed when present, even if there is only one copy. Recessive is only expressed when two copies are present
43
What does homozygous and heterozygous mean, respectively?
Homozygous: the same alleles, heterozygous: different alleles
44
What does genotype and phenotype mean, respectively?
Genotype: the genes you have. Phenotype: how those genes are expressed
45
What does incomplete dominance and codominance mean, respectively?
Incomplete dominance: Neither allele is dominant, and the resulting phenotype is a blend of both traits. Codominance: when both alleles are fully expressed in the phenotype, showing both traits side by side
46
What does pleiotropy and polygenic inheritance mean, respectively?
Pleiotropy: When one gene affects multiple, unrelated traits in an organism. Polygenic inheritance: when multiple genes work together to influence a single trait
47
Are ribosomes the sites of translation?
Yes
48
Does DNA have deoxyribose, and is generally double-stranded?
Yes
49
Does RNA have ribose, and is generally single-stranded?
Yes
50
Does the complimentary base pairing make it possible to generate two identical copies of each DNA molecule in a cell preparing to divide?
Yes
51
What bases are present as pyrimidines and purines respectively?
Pyrimidines (cytosine, thymine, uracil): single six membraned ring, purines (adenine and guanine): six-membered ring fused to a five-membraned ring
52
How do you form a nucleoside, and nucleotide?
Nucleoside: nitrogenous base + (pentose) sugar, nucleotide: nucleoside + phosphate group
53