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Neuropharmacology > test 3 > Flashcards

test 3 Flashcards

(51 cards)

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1
Q

Alpha 1 Receptors (NE, EPI)

A

Alpha 1A, Alpha 1B, and Alpha 1D

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2
Q

Alpha 1A, Alpha 1B, and Alpha 1D NON-SELECTIVE AGONIST

NE, EPI

A

-DA, NE, Epinephrine, Phenylephrine, Ephederine, Pseudoephedrine

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3
Q

Alpha 1A
SELECTIVE AGONIST
(NE, EPI)

A

TETRAHYDRAZOLINE

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4
Q

Alpha 1A, Alpha 1B, and Alpha 1D NON-SELECTIVE ANTAGONIST

NE, EPI

A
  • Phentolamine

- Prazosin

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5
Q

Alpha 1A, Alpha 1B, and Alpha 1D SUICIDE ANTAGONIST

NE, EPI

A

Phenoxybenzamine

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6
Q

Alpha-1: Gq – excitatory

NE, EPI

A

Activate PLC –> Increases PKC activity–> Increases cAMK-2

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7
Q

Alpha-2: Gi -Inhibitory

A

Decreases PKA activity

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8
Q

Alpha 2A, Alpha 2B, and Alpha 2C NON-SELECTIVE AGONIST

NE, EPI

A

NE, Epinephrine, and Clonidine

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9
Q

Alpha 2A
PARTIAL AGONIST
(NE, EPI)

A

-LSD-25

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10
Q

Alpha 2A, Alpha 2B, and Alpha 2C NON-SELECTIVE ANTAGONIST

NE, EPI

A

PHENTOLAMINE, PRAZOSIN, YOHIMBINE

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11
Q

ALPHA 2 RECEPTOR

G-protein Alpha subunit

A

-Gi

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12
Q

ALPHA 2 RECEPTOR

Beta/gama subunit

A
  • Inhibit –> VDCCs

- Activate–>CDKCs

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13
Q

Beta receptors are

A

Beta1, Beta2, and Beta3

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14
Q

Beta1, Beta2, and Beta3

Non-Selective Agonists

A

NE, Epinephrine, Isoproterenol, ephedrine, clenbuterol

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15
Q

Beta2

Selective Agonists

A
  • Albuterol

- Salmeterol

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16
Q

Beta1, Beta2, and Beta3

Non- Selective Antagonists

A

PROPRANOLOL

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17
Q

Beta1, Beta2, and Beta3

Selective Antagonists

A

Atenolol

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18
Q

Beta1, Beta2, and Beta3 G-protein

A

Gs

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19
Q

5-HT1 receptors

A

5-HT 1A, 5-HT 1B, 5-HT 1D

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20
Q

5-HT 1A, 5-HT 1B, 5-HT 1D

NON-SELECTIVE AGONIST

A

5-HT and QUIPAZINE

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21
Q

5-HT 1A

Selective agonist

22
Q

5-HT 1B, 5-HT 1D

Selective Agonist

Study These Flashcards
A
  • ERGOTAMINE

- SUMATRIPTAN

23
Q

5-HT 1A, 5-HT 1B, 5-HT 1D

SELECTIVE ANTAGONIST

24
Q

5-HT 1A, 5-HT 1B, 5-HT 1D

G-Protein

25
5-HT 2 RECEPTORS
5-HT 2A, 5-HT 2B, 5-HT 2C
26
5-HT 2A, 5-HT 2B, 5-HT 2C | NON-SELECTIVE AGONIST
5-HT | QUIPAZINE
27
5-HT 2A | PARTIAL AGONIST
LSD-25 | PSILOCYBIN/PSILOCIN
28
5-HT 2A_______, 5-HT 2C____ | SELECTIVE AGONIST
- DMT | - AGOMELATINE
29
5-HT 2A | SELECTIVE ANTAGONIST
-ketanserin
30
5-HT 2B | SELECTIVE ANTAGONIST
METERGOLINE
31
5-HT 2C | SELECTIVE ANTAGONIST
RITANSERIN
32
5-HT 2A, 5-HT 2B, 5-HT 2C | NON-SELECTIVE ANTAGONIST
- Mesulergine | - Dibenzyline
33
5-HT 2A, 5-HT 2B, 5-HT 2C | G-protein
Gq
34
5-HT3 RECEPTORS
5-HT 3A | 5-HT 3B
35
5-HT 3A and 5-HT 3B | Non-Selective agonist
5-HT | QUIPAZINE
36
5-HT 3A and 5-HT 3B | Selective agonist
CBG
37
5-HT 3A and 5-HT 3B | Selective antagonist
Ondansetron
38
5-HT 3A and 5-HT 3B | Mechanism
Mostly a sodium cation channel
39
5-HT RECEPTOR
5-HT4, 5-HT6, and 5-HT7
40
5-HT4, 5-HT6, and 5-HT7 | NON-SELESCTIVE AGONIST
5-HT | QUIPAZINE
41
5-HT 6 and 5-HT 7 | NON SELECTIVE ANTAGONIST
CLOZAPINE
42
5-HT4, 5-HT6, and 5-HT7 | G-Protein
Gs
43
Histamine (HA) Receptors
H1, H2, H3, H4
44
H1 G-Protein (Post syn)
Gq | -Mast cells
45
H2 G-Protein (Post Syn)
Gs | -Parietal cells
46
H3_____ and H4 G-Protein | Both pre and Post
Gi H3: Is an Autoreceptor -H4: Tissue (Bone marrow, neutrophils, basophils)
47
Histamine (HA) agonist for H1-H4
Histamine
48
Histamine (HA) agonist for H2
Dimaprite
49
Histamine (HA) agonist for H3 &H4
Imetit
50
Histamine (HA) Antagonist for H2
CIMETIDINE
51
Histamine (HA) Antagonist for H3
CLOBENPROPIT ** | PHENOPROPIT

Neuropharmacology (1 decks)

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