Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Biological Basis Of Behavior > Test 4 > Flashcards

Test 4 Flashcards

1
Q

Prions

A

Misfolded protein, causes degeneration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Sporadic

A

Rare, not genetic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Capases

A

Killer enzyme, helps with apoptosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Lewy bodies

A

Abnormal circular structures with dense core, found in cytoplasm of nigrostriatal neurons in PD patients

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

A-synuclein

A

Involved in synaptic plasticity, cause of neural degeneration in PD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Toxic gain of function

A

Dominant mutation involved in faulty gene that produces protein with toxic effects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Parkin

A

Mutated, causes familial PD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Loss of function

A

Genetic disorder caused by recessive gene that fails to produce protein necessary for good health

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Proteasomes

A

Destroys faulty proteins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Ubiquitin

A

Protein that attaches itself to faulty proteins and targets them for destruction by proteasomes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Internal division of the globes pallid is (GPi)

A

Provides inhibitory input to motor cortex through thalamus, can be lesions to treat PD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Deep brain stimulation (DBS)

A

Implanting electrodes into basal ganglia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Fatal contagious brain disease

A

Mad cow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Dementia

A

Deterioration of intellectual abilities resulting from an organic brain disorder

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Alzheimer’s disease

A

Degenerative brain disorder of unknown origin, causes progressive memory loss, motor deficits, and eventual death

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Amyloid plaques

A

Extra cellular deposits that consist of a dense core of beta-amyloid, surrounded by degenerating axons/dendrites and activated microglia/astrocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Beta amyloid

A

Protein found in excessive amounts in brains of Alzheimer’s patients

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Neurofibrillary tangles

A

Dying neurons containing accumulations of misfolded tau protein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Tau protein

A

Normally component of micro tubules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Beta-amyloid precursor protein (APP)

A

Precursor for beta-amyloid protein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Secretases

A

Enzymes that cut beta-amyloid precursor into smaller pieces

22
Q

Presenilin

A

Protein that causes beta- amyloid precursor to be converted into short form

23
Q

ApoE

A

Glycoprotein that transports cholesterol in the blood and plays role in cellular repair

24
Q

Schizophrenia

A

Disordered thoughts, delusions, hallucinations, other bizarre behaviors

25
Q

Positive symptoms

A

Evident by presence. Delusions, hallucinations, thought disorders

26
Q

Thought disorder

A

Disorganized, irrational thinking

27
Q

Delusions

A

Beliefs obviously contrary to fact

28
Q

Hallucinations

A

Perceptions of stimuli that are not actually present

29
Q

Negative symptoms

A

Absence. Flattened emotional response, poverty of speech, lack of initiative/persistence, social withdrawal

30
Q

Cognitive symptoms

A

Deficits in learning/memory, poor abstract thinking, poor problem solving

31
Q

Epidemiology

A

Study of distribution/ causes of diseases in populations

32
Q

Seasonality effect

A

Increased incidence of schizophrenia in people born in late winter/early spring

33
Q

Hypofrontality

A

Decreased activity of prefrontal cortex, responsible for negative symptoms of schizophrenia

34
Q

Partial agonist

A

Drug that has very high affinity for receptor, but activates it less than a regular Logan’s. Agonist for low concentration, antagonist for high concentration

35
Q

Disordered feelings

A

Major affective disorders

36
Q

Bipolar disorder

A

Cyclical periods of mania/depression

37
Q

Major depressive disorder (MDD)

A

Unremitting depression with no mania

38
Q

Tricyclic antidepressants

A

Inhibit reuptake of NE and 5HT, affects other NTs too

39
Q

Specific serotonin reuptake inhibitors (SSRI)

A

Inhibits reuptake of 5HT, doesn’t affect any other NTs

40
Q

Serotonin and norepinephrine reuptake inhibitors (SNRI)

A

Inhibits reuptake of NE and 5HT, doesn’t affect any other NTs

41
Q

Electroconvulsive therapy (ECT)

A

Alleviates severe depression, electrical shock that causes seizure

42
Q

Subgenual anterior cingulate cortex (subgenual ACC)

A

DBS, plays role in depression symptoms

43
Q

Lithium

A

Treats bipolar disorder

44
Q

Monoamine hypothesis

A

Depression is caused by insufficient activity of monoaminergic neurons

45
Q

Tryptophan depletion procedure

A

Decreases 5HT synthesis

46
Q

Seasonal affective disorder (SAD)

A

Depression during winter

47
Q

Phototherapy

A

Treats SAD, exposes people to bright light for several hours a day

48
Q

Negative reinforcement

A

Removal of aversive stimulus

49
Q

Tolerance

A

Decreased sensitivity to a drug that comes from continued use

50
Q

Withdrawal symptom

A

Opposite effects of drugs

Biological Basis Of Behavior (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions